Results 41 to 50 of about 354,557 (333)
Matrix Metalloproteinases and Glaucoma Treatment. [PDF]
, 2020 Matrix metalloproteinases (MMPs) are a family of proteolytic enzymes that degrade extracellular matrix (ECM) components such as collagen and have important roles in multiple biological processes, including development and tissue remodeling, both in ...
Dibas, Mohammed +3 more
core
ADAMTS proteinases: a multi-domain, multi-functional family with roles in extracellular matrix turnover and arthritis [PDF]
, 2005 Members of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) family are known to influence development, angiogenesis, coagulation and progression of arthritis.
Jones, GC, Riley, GP
core +2 more sources
Inhibitory antibodies designed for matrix metalloproteinase modulation [PDF]
, 2019 The family of matrix metalloproteinases (MMPs) consists of a set of biological targets that are involved in a multitude of severe pathogenic events such as different forms of cancers or arthritis.
Fischer, Thomas, Riedl, Rainer
core +1 more source
Bindarit inhibits human coronary artery smooth muscle cell proliferation, migration and phenotypic switching [PDF]
, 2012 Bindarit, a selective inhibitor of monocyte chemotactic proteins (MCPs) synthesis, reduces neointimal formation in animal models of vascular injury and recently has been shown to inhibit in-stent late loss in a placebo-controlled phase II clinical trial.
Angelo Guglielmotti +12 more
core +11 more sources
Toxins, 2021 Scyphozoan envenomation is featured as severe cutaneous damages due to the toxic effects of venom components released by the stinging nematocysts of a scyphozoan.
Yang Yue +3 more
doaj +1 more source
Inhibition of Trophoblast-Induced Spiral Artery Remodeling Reduces Placental Perfusion in Rat Pregnancy. [PDF]
, 2010 Rats harboring the human angiotensinogen and human renin genes develop preeclamptic features in pregnancy. The preeclamptic rats exhibit a deeper trophoblast invasion associated with a reduced resistance index by uterine Doppler.
Cartwright, JE +12 more
core +1 more source
Toxins, 2022 We previously demonstrated that Nemopilema nomurai jellyfish venom metalloproteinases (JVMPs) play a key role in the toxicities induced by N. nomurai venom (NnV), including dermotoxicity, cytotoxicity, and lethality. In this study, we identified two full-
Du Hyeon Hwang +9 more
doaj +1 more source
, 2001 Matrix metalloproteinases (MMPs) is a family of collagenolytic enzymesand are associated with many pathological conditions. Especially, MMPs have a strong relation with tumor progression and invasion. In this review, we focused on association of MMPs and
Ichimura, Mitsuko +6 more
core +1 more source
Hyperhomocysteinemia induced by excessive methionine intake promotes rupture of cerebral aneurysms in ovariectomized rats. [PDF]
, 2016 BackgroundHyperhomocysteinemia (HHcy) is associated with inflammation and a rise in the expression of matrix metalloproteinase-9 (MMP-9) in the vascular wall.
Hashimoto, Tomoki +9 more
core +2 more sources
Zymography of Metalloproteinases
Current Protocols in Protein Science, 2003 AbstractZymography is an electrophoretic technique enabling visualization of the number and approximate size of peptidases in a sample on the basis of their hydrolysis of a protein substrate within the gel. The technique is particularly useful for analyzing the peptidase composition of complex biological samples because visualization depends directly ...
Troeberg, L, Nagase, H
openaire +2 more sources