Results 61 to 70 of about 182,335 (266)

Morphometry and Immunoexpression of Metalloproteinase 2 and Its Inhibitor in the Fibrotic and Non-Fibrotic Grafted Kidney—Digital Analysis

Biomedicines
Background: Metalloproteinases (MMPs), together with their tissue inhibitors (TIMPs), regulate the extracellular matrix (ECM) in various tissues. MMP-2 and TIMP-2 maintain this process in renal tissue.
Dagmara Szypulska-Koziarska, Ewa Kwiatkowska, Martyna Opara-Bajerowicz, Aleksandra Wilk   +3 more
doaj   +1 more source

Ultrathin Hydrogel Membranes Inspired by Soap Films Enable Physiologically Relevant Breathing Lung Models

Advanced Materials, EarlyView.
A soap‐film inspired strategy enables the fabrication of ultrathin yet robust GelMA‐PAAm membranes for breathing lung culture. The hydrogel membrane supports long‐term cyclic deformation under air‐liquid interface conditions, enabling physiologically relevant breathing motions of engineered lung tissue culture. ABSTRACT Breathing continuously stretches
Yunji Lee, Gwang Myeong Kim, Wookyeom Kim, Fenny Soetanto, Gyungin Ryu, Taehun Chung, Youn Soo Kim, Junmin Lee, Hwa‐Rim Lee, Sungjune Jung   +9 more
wiley   +1 more source

Snake Venom Metalloproteinases (SVMPs): A structure-function update

Toxicon: X, 2020
Snake venom metalloproteinases (SVMPs) represent a diverse group of multi-domain proteins with several biological activities such as the ability to induce hemorrhage, proteolytic degradation of fibrinogen and fibrin, induction of apoptosis and inhibition
Olamide Tosin Olaoba, Patty Karina dos Santos, Heloisa Sobreiro Selistre-de-Araujo, Dulce Helena Ferreira de Souza   +3 more
doaj   +1 more source

Extrusion Bioprinting for Wound Healing: Innovations in Functionalized Bioinks and Bioprinting Technology

Advanced Materials Technologies, EarlyView.
Extrusion‐based bioprinting (EBB) has emerged as a versatile biofabrication platform capable of precisely depositing bioinks composed of biomaterials, cells, and bioactive agents to generate patient‐specific, biomimetic skin constructs. This paper presents a state‐of‐the‐art and forward‐looking overview of EBB for wound healing, encompassing printing ...
Hien‐Phuong Le, Anh Tuan Trong Tran, Ammara Waheed, Tran Thanh Tung, Dusan Losic   +4 more
wiley   +1 more source

3D‐Printed Corneal Substitutes: Materials, Fabrication, and Preclinical Progress

Advanced Materials Technologies, EarlyView.
Successful clinical translation of 3D‐printed corneal substitutes relies on the interplay between the bioink properties, cellular component, and the fabrication process. These factors influence the critical properties of the construct, including optical transparency, mechanical stability, suture retention, that ultimately govern long‐term stromal ...
Shadi Moshayedi, Ashley Vazquez, Alexander J. Choi, Dimitrios Karamichos, Jayoung Kim   +4 more
wiley   +1 more source

Expression of Matrix Metalloproteinase, a Disintegrin and Metalloproteinase, and Tissue Inhibitor of Metalloproteinase in Human Chondrosarcoma

ACTA HISTOCHEMICA ET CYTOCHEMICA, 2004
Malignant degree of human chondrosarcoma can be difficult to determine using only histological findings. We therefore assessed expression of matrix metalloproteinases (MMPs), a disintegrin and metalloproteinase (ADAM) with thrombospondin motifs (ADAMTSs) and tissue inhibitor of metalloproteinases (TIMPs) in chondrosarcoma and ascertained relationships ...
Sugita, Hideyuki, Osaka, Shunzo, Toriyama, Masato, Osaka, Eiji, Yoshida, Yukihiro, Ryu, Junnosuke, Sano, Makoto, Sugitani, Masahiko, Nemoto, Norimichi   +8 more
openaire   +2 more sources

Spheroid‐On‐A‐Drop: A Modular Droplet Microfluidics Platform

Advanced Materials Technologies, EarlyView.
The proposed Spheroid‐on‐a‐Drop platform represents a reproducible and tunable platform for the fabrication of biocompatible GelMA‐based microgels, able to support controlled 3D tumor spheroid culture. Its precise control over droplet dynamics and cell distribution paves the way for advanced applications in tissue modeling, drug screening, and ...
A. Fergola, V. Vighetto, G. Mesiano, A. Cosola, S. L. Marasso, M. Cocuzza, C. F. Pirri, L. Napione, F. Frascella   +8 more
wiley   +1 more source

A Case-Control Study of Comparison of Plasma Levels of Matrix Metalloproteinase-9 in Inhaled Opium Addicts and Clinically Healthy Persons [PDF]

Addiction and Health, 2017
cancer invasion and lymphatic metastasis. Smoking has been reported to increase the metalloproteinase level, but the role of opium consumption in metalloproteinase level has not yet been examined.
Maryam Amizadeh, Shahryar Dabiri, Armin Javedan, Ali Eftekharian, Aliasghar Arabi   +4 more
doaj  

Chronic inflammation evoked by pathogenic stimulus during carcinogenesis

4 open, 2019
A pathogenic (biological or chemical) stimulus is the earliest information received by a cell that can result in the disruption of homeostasis with consequent development of disease.
Brücher Björn L.D.M., Jamall Ijaz S.
doaj   +1 more source

Matrix metalloproteinases and epileptogenesis [PDF]

Molecular and Cellular Pediatrics, 2014
Matrix metalloproteinases are vital drivers of synaptic remodeling in health and disease. It is suggested that at early stages of epileptogenesis, inhibition of matrix metalloproteinases may help ameliorate cell death, aberrant network rewiring, and neuroinflammation and prevent development of epilepsy.
openaire   +2 more sources