Results 261 to 270 of about 218,326 (315)

Plasma Desmosine Is Elevated in Thoracoabdominal Aortic Aneurysms and Is Associated with Intramural Proteolytic Activity. [PDF]

Int J Mol Sci
Doukas P, Bassett C, Hruschka B, Kuzmanova E, Wessels I, Klump HJ, Schurgers LJ, Jacobs MJ, Uhl C, Gombert A, Huang JTJ.   +10 more
europepmc   +1 more source

Analysis of the Role of Gene Variants in Matrix Metalloproteinases and Their Tissue Inhibitors in Bronchopulmonary Dysplasia (BPD): A Study in the Polish Population. [PDF]

Curr Issues Mol Biol
Szpecht D, Abu-Amara K, Kurzawinska G, Seremak-Mrozikiewicz A.   +3 more
europepmc   +1 more source

Tissue-Based Multiomic Exploratory Analysis of the Urokinase Plasminogen Activator/uPAR System and Matrix Metalloproteinases in Stroma AReactive Invasion Front Areas-Positive Gastrointestinal Cancers.

Pathobiology
Reitsam NG, Grosser B, Dintner S, Grozdanov V, Sommer F, Heyer C, Schlesner M, Hardt J, Franz S, Schenkirsch G, Probst A, Löhr P, Waidhauser J, Märkl B.   +13 more
europepmc   +1 more source

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Metalloproteinases and tissue inhibitors of metalloproteinases

Breast Cancer Research and Treatment, 1998
Because the proteolytic degradation of extracellular matrix is required for invasion and metastasis, it would appear that the important family of matrix metalloproteinases (MMPs) and their inhibitors (TIMPs) might be prognostic indicators of the invasive potential of a breast tumor.
M, Toi, S, Ishigaki, T, Tominaga
openaire   +2 more sources

Handling Metalloproteinases

Current Protocols in Protein Science, 2016
AbstractSubstrate cleavage by metalloproteinases involves nucleophilic attack on the scissile peptide bond by a water molecule that is polarized by a catalytic metal, usually a zinc ion, and a general base, usually the carboxyl group of a glutamic acid side chain.
Sven, Fridrich, Konstantin, Karmilin, Walter, Stöcker   +2 more
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Matrix Metalloproteinases

Current Protocols in Cell Biology, 2003
AbstractMatrix metalloproteinases are a class of enzymes that play an important role in the remodeling of the extracellular matrix in development and cancer metastasis. This unit describes a set of methods‐cell‐mediated dissolution of type I collagen fibrils, direct and reverse zymography, enzyme capture based on a‐2 macroglubulin and TIMP‐1 and ‐2 ...
Henning, Birkedal-Hansen, Susan, Yamada, Jack, Windsor, Anne Havemose, Poulsen, Guy, Lyons, William, Stetler-Stevenson, Bente, Birkedal-Hansen   +6 more
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Matrix Metalloproteinases

Current Protocols in Cell Biology, 2008
AbstractMatrix metalloproteinases are a class of enzymes that play an important role in the remodeling of the extracellular matrix in development and cancer metastasis. This unit describes a set of methods—cell‐mediated dissolution of type‐1 collagen fibrils, direct and reverse zymography, enzyme capture based on α2‐macroglobulin and TIMP‐1 and ‐2, and
Henning, Birkedal-Hansen, Susan, Yamada, Jack, Windsor, Anne Havernose, Pollard, Guy, Lyons, William, Stetler-Stevenson, Bente, Birkedal-Hansen   +6 more
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Tissue inhibitors of metalloproteinases and metalloproteinases in atherosclerosis

Current Opinion in Lipidology, 1998
The ability of the metalloproteinases to degrade extracellular matrix proteins is essential for the matrix remodelling that occurs during infiltration of inflammatory cells, intimal thickening, angiogenesis and plaque rupture which are a result of atherosclerosis.
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