Results 11 to 20 of about 22,892 (210)
CHIN117 is a dual cysteinyl leukotriene receptor 1 (CYSLTR1) antagonist and G‐protein‐coupled bile acid receptor 1 (GPBAR1) agonist. In the liver, GPBAR1 and CYSLTR1 are coexpressed by liver sinusoidal endothelial cells (LSECs), HSCs, circulating monocytes/macrophages, and liver resident macrophages (Kupffer cells).
Michele Biagioli +13 more
wiley +1 more source
Bioinformatics of Metalloproteins and Metalloproteomes
Trace metals are inorganic elements that are required for all organisms in very low quantities. They serve as cofactors and activators of metalloproteins involved in a variety of key cellular processes.
Yan Zhang, Junge Zheng
doaj +1 more source
Geobacter sulfurreducens’ Unique Metabolism Results in Cells with a High Iron and Lipid Content
Geobacter sulfurreducens is a ubiquitous iron-reducing bacterium in soils, and in engineered systems, it can respire an electrode to produce measurable electric current.
Ethan Howley +3 more
doaj +1 more source
Synchrotron structural biology at SSRL, the beginning and beyond. [PDF]
It has been 50 years since the publication in PNAS of our first results on the utilization and demonstrated benefits of synchrotron radiation for macromolecular crystallography. In this brief article, I offer some personal observations and comments about that early research at Stanford and the Stanford Synchrotron Radiation Project (SSRP, later renamed
Hodgson K.
europepmc +2 more sources
Vibrational spectroscopy and in particular, resonance Raman (RR) spectroscopy, can provide molecular details on metalloproteins containing multiple cofactors, which are often challenging for other spectroscopies.
Célia M. Silveira +6 more
doaj +1 more source
Isolation of Acidic, Basic and Neutral Metalloproteins by QPNC-PAGE [PDF]
A standard protocol for isolating metalloproteins in complex biological samples is presented using quantitative preparative native continuous polyacrylamide gel electrophoresis (QPNC ...
Bernd Kastenholz, David E. Garfin
core +2 more sources
Conflicting interests in the pathogen-host tug of war : fungal micronutrient scavenging versus mammalian nutritional immunity [PDF]
Funding: The authors are supported by the European Research Council (STRIFE project funded on grant number ERC-2009-AdG-249793, http://erc.europa.eu). AJPB is also supported by the Wellcome Trust (grant numbers 080088, 097377, www.wellcome.ac.uk) and the
Ballou, Elizabeth R +3 more
core +2 more sources
Approximately one-third of all proteins have been estimated to contain at least one metal cofactor, and these proteins are referred to as metalloproteins.
Gabriel B Tristao +7 more
doaj +1 more source
Accurate quantification of selenoproteins in human plasma/serum by isotope dilution ICP-MS : focus on selenoprotein P [PDF]
Acknowledgements The research leading to these results was funded by the EMRP Joint Research Project “Metrology for metalloproteins” (HLT-05 2012). The EMRP is jointly funded by the EMRP participating countries within EURAMET and the European Union.Peer ...
Busto, M. Estela del Castillo +8 more
core +1 more source
The molecular toxicity of the uranyl ion (UO22+) in living cells is primarily determined by its high affinity to both native and potential metal-binding sites that commonly occur in the structure of biomolecules.
Egor S. Bulavko +2 more
doaj +1 more source

