Results 51 to 60 of about 22,558 (250)
Zinc: Multidimensional Effects on Living Organisms
Biomedicines, 2021 Zinc is a redox-inert trace element that is second only to iron in abundance in biological systems. In cells, zinc is typically buffered and bound to metalloproteins, but it may also exist in a labile or chelatable (free ion) form.
Math P. Cuajungco +2 more
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Kinetics of the reduction of metalloproteins by chromous ion [PDF]
, 1972 The reduction of Cu(330) in Rhus vernicifera laccase by chromous ion is 30% faster than reduction of Cu(614) at room temperature [pH 4.8, µ = 0.1 (NaCl)], and two parallel first-order paths, attributed to heterogeneity of the protein, are observed at ...
Dawson, J. W. +3 more
core
Metalloprotein‐based MRI probes [PDF]
FEBS Letters, 2013 Metalloproteins have long been recognized as key determinants of endogenous contrast in magnetic resonance imaging (MRI) of biological subjects. More recently, both natural and engineered metalloproteins have been harnessed as biotechnological tools to probe gene expression, enzyme activity, and analyte concentrations by MRI.
Matsumoto, Yuri, Jasanoff, Alan Pradip
openaire +5 more sources
Frontiers in Molecular Biosciences, 2019 The design of metal-binding sites in proteins that combine high affinity with high selectivity for the desired metal ion remains a challenging goal.
Marie Hoarau +4 more
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IUCrJ, 2016 Lytic polysaccharide monooxygenases (LPMOs) are a new class of microbial copper enzymes involved in the degradation of recalcitrant polysaccharides.
Kristian E. H. Frandsen, Leila Lo Leggio
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Artificial Enzymatic Electrochemistry
ChemElectroChem, EarlyView.Artificial enzymatic electrochemistry has emerged as an effective method to extend the catalytic abilities of enzymes. This review explores the bioelectrochemical methods used to understand and optimize the structure and function of artificial enzymes.
Nya E. Black +3 more
wiley +1 more source
Profiling the iron, copper and zinc content in primary neuron and astrocyte cultures by rapid online quantitative size exclusion chromatography-inductively coupled plasma-mass spectrometry [PDF]
, 2013 Metals often determine the chemical reactivity of the proteins to which they are bound. Each cell in the body tightly maintains a unique metalloproteomic profile, mostly dependent on function.
Bush, AI +12 more
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COMPUTATIONAL APPROACHES FOR RATIONAL DESIGN OF PROTEINS WITH NOVEL FUNCTIONALITIES
Computational and Structural Biotechnology Journal, 2012 Proteins are the most multifaceted macromolecules in living systems and have various important functions, including structural, catalytic, sensory, and regulatory functions.
Manish Kumar Tiwari +4 more
doaj +3 more sources
Angewandte Chemie, Volume 137, Issue 43, October 20, 2025.Bio‐inspired symmetry disruption in aqueous Zn‐ion batteries: Isobutyramide simultaneously breaks hydrogen‐bonding networks and coordinates Zn2+ ions, tailoring solvation structure and stabilizing Zn anodes. This molecular‐level electrolyte engineering suppresses dendrites, mitigates hydrogen evolution, and enables long‐lasting, high‐performance ...
Wei Zhang +14 more
wiley +2 more sources
ChemMedChem, EarlyView.Docking and molecular dynamics simulations within CYP2E1 clarify the structural basis for the reduced hepatotoxicity of novel non‐opioid analgesics developed as safer alternatives to acetaminophen. The results reveal that hydrophobicity and substituent size critically influence binding conformations, thereby modulating toxicity.
Claire Coderch +5 more
wiley +1 more source