Results 61 to 70 of about 9,549 (181)
Macroscopic Convective Fluid Flows Arising From Binding of Ions and Small Molecules to Proteins
Small, EarlyView.The interaction of ions or small molecules with proteins causes convective flows due to the displacement of water from the hydration shell. As shown, the replacement of the nickel ion removed from urease by EDTA pre‐treatment results in binding‐induced convective fluid flow.
Shanid Babu Shrestha +4 more
wiley +1 more source
Uranyl Binding to Proteins and Structural-Functional Impacts
Biomolecules, 2020 The widespread use of uranium for civilian purposes causes a worldwide concern of its threat to human health due to the long-lived radioactivity of uranium and the high toxicity of uranyl ion (UO22+).
Ying-Wu Lin
doaj +1 more source
Environmental Toxicology, EarlyView.ABSTRACT Copper is an environmental contaminant capable of disrupting redox homeostasis and impairing antioxidant defenses in aquatic organisms, thereby increasing susceptibility to oxidative stress. The cystine/glutamate antiporter (system xc−) plays a central role in maintaining intracellular glutathione (GSH) levels, a major antioxidant defense ...
Maria Vitória Takemura Mariano +9 more
wiley +1 more source
Plant Biology, EarlyView.Common bean genotypes differ in their iron acquisition through distinct Strategy I responses and root exudation patterns. Abstract Iron (Fe) deficiency in food crops, particularly on calcareous soils, limits productivity and human nutrition. This study investigated two common bean (Phaseolus vulgaris) genotypes, Guaymí (high Fe‐accumulating, HI) and ...
F. X. Rucamumihigo +4 more
wiley +1 more source
Metalloprotein‐based MRI probes [PDF]
FEBS Letters, 2013 Metalloproteins have long been recognized as key determinants of endogenous contrast in magnetic resonance imaging (MRI) of biological subjects. More recently, both natural and engineered metalloproteins have been harnessed as biotechnological tools to probe gene expression, enzyme activity, and analyte concentrations by MRI.
Matsumoto, Yuri, Jasanoff, Alan Pradip
openaire +4 more sources
Testing the limits: serial crystallography using unpatterned fixed targets
IUCrJSheet-on-sheet (SOS) fixed-target chips are arguably the most versatile, cheapest and simplest sample-delivery method for ambient-temperature data acquisition using serial crystallography approaches at synchrotrons and X-ray free-electron lasers (XFELs).
Alexander Gorel +12 more
doaj +1 more source
eLife, 2015 Dinitrogen reduction in the biological nitrogen cycle is catalyzed by nitrogenase, a two-component metalloenzyme. Understanding of the transformation of the inert resting state of the active site FeMo-cofactor into an activated state capable of reducing ...
Thomas Spatzal +3 more
doaj +1 more source
Periodontology 2000, EarlyView.Abstract Peri‐implant diseases are dysbiosis‐mediated inflammatory disorders that occur in susceptible hosts. Antimicrobials and immunomodulatory agents therefore might be pertinent as adjunctive measures in the treatment of such disorders. The aim of this narrative review was to examine the existing evidence and assess the effectiveness of emerging ...
Alberto Monje +3 more
wiley +1 more source
Endopeptidase Regulation as a Novel Function of the Zur-Dependent Zinc Starvation Response
mBio, 2019 The cell wall is a strong, yet flexible, meshwork of peptidoglycan (PG) that gives a bacterium structural integrity. To accommodate a growing cell, the wall is remodeled by both PG synthesis and degradation.
Shannon G. Murphy +6 more
doaj +1 more source