Results 51 to 60 of about 9,549 (181)

Oxidation of Allylic Alcohols by Manganese Oxides: Elucidating the Influences of MnOx Structure and Mn Oxidation State on Reactivity

Chemistry – A European Journal, EarlyView.
Manganese oxides (MnOX) of different structures and with different Mn oxidation states exhibit significant variation in their reactivity toward the oxidation of allylic alcohols. Using two allylic alcohol model substrates, we demonstrate the relationship between activity and MnOX structure, Mn4+ content and incorporated secondary cations.
Erdogan Kasisari, Leandra Meyer, S. Esmael Balaghi, Harald Scherer, Patrick Elsässer, Anna Fischer, Philipp Kurz   +6 more
wiley   +1 more source

A Structure-Based Analysis of the Evolution of Transcription Factors of the FNR/CRP Family

Biomolecules
The X-ray structural analysis of the N-terminal domain cavity from eleven transcription regulators (TFs) of the Fumarate Nitrate Reduction regulator/cAMP Regulator Protein family shows several significant trends.
Juan C. Fontecilla-Camps
doaj   +1 more source

NMR of Paramagnetic Proteins: ¹³C Derived Paramagnetic Relaxation Enhancements Are an Additional Source of Structural Information in Solution

Magnetochemistry, 2023
In paramagnetic metalloproteins, longitudinal relaxation rates of 13C′ and 13Cα nuclei can be measured using 13C detected experiments and converted into electron spin-nuclear spin distance restraints, also known as Paramagnetic Relaxation Enhancement ...
Leonardo Querci, Inês B. Trindade, Michele Invernici, José Malanho Silva, Francesca Cantini, Ricardo O. Louro, Mario Piccioli   +6 more
doaj   +1 more source

Turning Bonding Into Function: The Emerging Role of the Bioactive Selenium─Metal Motif in Toxicology and Medicinal Chemistry

Chemistry – A European Journal, EarlyView.
Balancing Act: Se─M bond serving as the fulcrum of the balance scale to compare the different weight of toxicity and therapeutic effects in biological environment. ABSTRACT The synthesis and characterization of organo‐selenium compounds have attracted considerable interest for decades, driven by the search for efficient catalysts and bioinspired ...
Matteo Filippi, Alessandro Rubbi, Pablo A. Nogara, Giovanni Ribaudo, Vito Lippolis, João B. T. Rocha, Laura Orian   +6 more
wiley   +1 more source

Automatically Constructed Neural Network Potentials for Molecular Dynamics Simulation of Zinc Proteins

Frontiers in Chemistry, 2021
The development of accurate and efficient potential energy functions for the molecular dynamics simulation of metalloproteins has long been a great challenge for the theoretical chemistry community.
Mingyuan Xu, Tong Zhu, Tong Zhu, John Z. H. Zhang, John Z. H. Zhang, John Z. H. Zhang, John Z. H. Zhang   +6 more
doaj   +1 more source

Carbon Dot-Mediated Capillary Electrophoresis Separations of Metallated and Demetallated Forms of Transferrin Protein

Molecules, 2019
Carbon dots (CDs) are fluorescent nanomaterials used extensively in bioimaging, biosensing and biomedicine. This is due in large part to their biocompatibility, photostability, lower toxicity, and lower cost, compared to inorganic quantum dots or organic
Leona R. Sirkisoon, Honest C. Makamba, Shingo Saito, Christa L. Colyer   +3 more
doaj   +1 more source

A Personal Perspective on Metalloprotein Structure and the Future of Macromolecular X‐Ray Crystallography

Journal of the Chinese Chemical Society, EarlyView.
While X‐ray crystallography has been the primary method for determining the structures of metalloproteins, cryoEM has taken over this role, illustrated by [4Fe4S]‐cluster containing proteins deposited in the Protein Data Bank. What will be the role for X‐ray crystallography as cryoEM and machine learning methods dominate the initial structural analysis?
Douglas C. Rees
wiley   +1 more source

Paramagnetic NMR Spectroscopy Is a Tool to Address Reactivity, Structure, and Protein–Protein Interactions of Metalloproteins: The Case of Iron–Sulfur Proteins

Magnetochemistry, 2020
The study of cellular machineries responsible for the iron–sulfur (Fe–S) cluster biogenesis has led to the identification of a large number of proteins, whose importance for life is documented by an increasing number of diseases linked to them.
Mario Piccioli
doaj   +1 more source

Precision Medicine in Neurodegeneration with Brain Iron Accumulation (NBIA) Disorders: An Update on Emerging Treatments

Movement Disorders Clinical Practice, EarlyView.
Abstract Background Neurodegeneration with Brain Iron Accumulation (NBIA) is a heterogeneous group of heritable, mostly recessive, progressive neurodegenerative diseases characterized by iron deposition in the basal ganglia and brainstem. There are no solid global epidemiological data on prevalence and incidence of NBIA subtypes, but registry data and ...
Susanne A. Schneider, Divyani Garg, Vassilena Iankova, Thomas Klopstock   +3 more
wiley   +1 more source

Decorin Is a Zn2+ Metalloprotein [PDF]

Journal of Biological Chemistry, 1999
Decorin is ubiquitously distributed in the extracellular matrix of mammals and a member of the proteoglycan family characterized by a core protein dominated by leucine-rich repeat motifs. We show here that decorin extracted from bovine tissues under denaturing conditions or produced in recombinant "native" form by cultured mammalian cells has a high ...
V W, Yang, S R, LaBrenz, L C, Rosenberg, D, McQuillan, M, Höök   +4 more
openaire   +2 more sources