Results 51 to 60 of about 14,121 (262)
Frontiers in Microbiology, 2018 The phytopathogenic bacteria, Pseudomonas syringae pv. lapsa (P. syringae pv. lapsa) infects the staple food crop wheat. Metalloproteins play important roles in plant-pathogen interactions. Hence, the present work is aimed to predict and analyze the iron
Ankita Sharma +2 more
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Uranyl Binding to Proteins and Structural-Functional Impacts
Biomolecules, 2020 The widespread use of uranium for civilian purposes causes a worldwide concern of its threat to human health due to the long-lived radioactivity of uranium and the high toxicity of uranyl ion (UO22+).
Ying-Wu Lin
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Frontiers in Molecular Biosciences, 2019 The design of metal-binding sites in proteins that combine high affinity with high selectivity for the desired metal ion remains a challenging goal.
Marie Hoarau +4 more
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Reflections on the Origin of Coded Protein Biosynthesis
BiomoleculesThe principle of continuity posits that some central features of primordial biocatalytic mechanisms should still be present in the genetically dependent pathway of protein synthesis, a crucial step in the emergence of life.
Juan Carlos Fontecilla-Camps
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IUCrJ, 2016 Lytic polysaccharide monooxygenases (LPMOs) are a new class of microbial copper enzymes involved in the degradation of recalcitrant polysaccharides.
Kristian E. H. Frandsen, Leila Lo Leggio
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High-resolution electrochemical STM of redox metalloproteins [PDF]
, 2017 Electrochemical studies of redox active metalloproteins have become an increasingly fruitful area of study in recent years, particularly with the single-molecule resolution capability of electrochemical scanning tunnelling microscopy (EC-STM) which ...
Elliott, Martin, Martin Elliott
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Biotechnology and Applied Biochemistry, EarlyView.ABSTRACT Neisseria gonorrhoeae poses an urgent public health challenge due to rapidly increasing antimicrobial resistance and the absence of an effective vaccine. Targeting conserved bacterial pathways involved in essential physiological processes may provide new opportunities for vaccine antigen discovery.
Sinethemba H. Yakobi +1 more
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Journal of the Chinese Chemical Society, EarlyView.While X‐ray crystallography has been the primary method for determining the structures of metalloproteins, cryoEM has taken over this role, illustrated by [4Fe4S]‐cluster containing proteins deposited in the Protein Data Bank. What will be the role for X‐ray crystallography as cryoEM and machine learning methods dominate the initial structural analysis?
Douglas C. Rees
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COMPUTATIONAL APPROACHES FOR RATIONAL DESIGN OF PROTEINS WITH NOVEL FUNCTIONALITIES
Computational and Structural Biotechnology Journal, 2012 Proteins are the most multifaceted macromolecules in living systems and have various important functions, including structural, catalytic, sensory, and regulatory functions.
Manish Kumar Tiwari +4 more
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Quadrupolar metal ion NMR studies of metalloproteins
, 1998 We present a summary of the quadrupolar metal ion NMR studies of metalloproteins conducted in our laboratory in recent years. The approaches we employ can be subdivided into two categories: (i) the use of low-frequency metal nuclei to probe metal ion ...
Hans J Vogel, James M Aramini
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