Results 61 to 70 of about 22,558 (250)

Reflections on the Origin of Coded Protein Biosynthesis

Biomolecules
The principle of continuity posits that some central features of primordial biocatalytic mechanisms should still be present in the genetically dependent pathway of protein synthesis, a crucial step in the emergence of life.
Juan Carlos Fontecilla-Camps
doaj   +1 more source

Engineering tyrosine-based electron flow pathways in proteins: The case of aplysia myoglobin [PDF]

, 2012
Tyrosine residues can act as redox cofactors that provide an electron transfer ("hole-hopping") route that enhances the rate of ferryl heme iron reduction by externally added reductants, for example, ascorbate.
Alayash A. I., Alayash A. I., Aubert C., Bolognesi M., Brandon J. Reeder, Chris E. Cooper, Dimitri A. Svistunenko, Egmond M. R., Ekberg M., Ekberg M., Gray H. B., Holt S., Lardinois O. M., McLeod L. L., Michael T. Wilson, Moore K. P., Natanson C., Nilges M. J., Peisach J., Reece S. Y., Reeder B. J., Reeder B. J., Reeder B. J., Reeder B. J., Reeder B. J., Reeder B. J., Reeder B. J., Rogers M. S., Rova U., Rova U., Seyedsayamdost M. R., Shih C., Silaghi-Dumitrescu R., Stubbe J., Svistunenko D. A., Svistunenko D. A., Svistunenko D. A., Thompson M. K., Wilbur D. J., Yee C. S.   +39 more
core   +1 more source

Molecular dynamics simulations of metalloproteins: A folding study of rubredoxin from Pyrococcus furiosus

AIMS Biophysics, 2018
The constant increase of computational power has made feasible to investigate the folding mechanism of small proteins using molecular dynamics (MD). Metal-binding proteins (metalloproteins) are usually complicated to model, largely due to the presence of
Davide Sala, Andrea Giachetti, Antonio Rosato   +2 more
doaj   +1 more source

Liebig Review: Legume–Rhizobium Symbiosis Under Selenium Fertilization: A Unique Dual Function in the Plant–Soil System

Journal of Plant Nutrition and Soil Science, EarlyView.
ABSTRACT Background Selenium (Se) plays a vital role as a beneficial element in promoting the production of leguminous plants. It influences legume quality by improving crop nutritive value and contributing to human and animal health. Literature Review This review is timely, as there are gaps in understanding Se–rhizobia interactions in legumes, which ...
Muna Ali Abdalla, Saad Sulieman, Karl Hermann Mühling   +2 more
wiley   +1 more source

Metalloprotein Crystallography: More than a Structure [PDF]

, 2015
Metal ions and metallocofactors play important roles in a broad range of biochemical reactions. Accordingly, it has been estimated that as much as 25–50% of the proteome uses transition metal ions to carry out a variety of essential functions.
Bowman, Sarah E. J., Drennan, Catherine L., Rabb, Jennifer   +2 more
core   +1 more source

Metal‐Coordination Specificity and Structural Dynamics of C. elegans Metallothionein I: Insights From 3D Modeling and MD Simulations

Proteins: Structure, Function, and Bioinformatics, EarlyView.
ABSTRACT Metallothioneins (MTLs) are small, cysteine‐rich proteins known for their ability to bind metal ions and exhibit flexible, disordered structures. The structural and functional characteristics of metallothionein I (MTL‐1) from Caenorhabditis elegans were investigated, focusing on its behavior in both metal free (MTL‐1 Apo) and metal‐bond states
Nilvea Ramalho de Oliveira, Andrei Santos Siqueira, Paulo Sérgio Alves Bueno, Evonnildo Costa Gonçalves, Juliano Zanette   +4 more
wiley   +1 more source

Proton NMR Spectroscopy as a Probe of Dinuclear Copper(II) Active Sites in Metalloproteins. Characterization of the Hyperactive Copper(II)-Substituted Aminopeptidase from \u3cem\u3eAeromonas proteolytica\u3c/em\u3e [PDF]

, 1998
Proton NMR spectra of the hyperactive Cu(II)-substituted aminopeptidase from Aeromonas proteolytica (AAP) were recorded in both H2O and D2O buffered solution at pH 6.7.
Bennett, Brian, Chen, Guanjing, Holz, Richard C., Ming, Li-June   +3 more
core   +1 more source

Ab initio analysis of the x-ray absorption spectrum of the myoglobin-carbon monoxide complex: Structure and vibrations

, 2010
We present a comparison between Fe K-edge x-ray absorption spectra of carbonmonoxy-myoglobin and its simulation based on density-functional theory determination of the structure and vibrations and spectral simulation with multiple-scattering theory.
Boscherini, F., Boschi, C. Degli Esposti, Ferrari, L., Rehr, J. J., Venturoli, G., Veronesi, G., Vila, F. D.   +6 more
core   +1 more source

Electronic structure and correlations of vitamin B12 studied within the Haldane-Anderson impurity model [PDF]

, 2015
We study the electronic structure and correlations of vitamin B12 (cyanocobalamine) by using the framework of the multi-orbital single-impurity Haldane-Anderson model of a transition-metal impurity in a semiconductor host. The parameters of the effective
Bulut, Nejat, Kandemir, Zafer, Mayda, Selma   +2 more
core   +2 more sources

Carbon Dot-Mediated Capillary Electrophoresis Separations of Metallated and Demetallated Forms of Transferrin Protein

Molecules, 2019
Carbon dots (CDs) are fluorescent nanomaterials used extensively in bioimaging, biosensing and biomedicine. This is due in large part to their biocompatibility, photostability, lower toxicity, and lower cost, compared to inorganic quantum dots or organic
Leona R. Sirkisoon, Honest C. Makamba, Shingo Saito, Christa L. Colyer   +3 more
doaj   +1 more source