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Metallothionein: A Comprehensive Review of Its Classification, Structure, Biological Functions, and Applications [PDF]

Antioxidants
Metallothionein is a cysteine-rich protein with a high metal content that is widely found in nature. In addition to heavy metal detoxification, metallothionein is well known as a potent antioxidant.
Ruoqiu Yang, Dumila Roshani, Boya Gao, Pinglan Li, Nan Shang   +4 more
doaj   +2 more sources

Metallothionein Protein Modeling from Pseudomonas aeruginosa PAO1 as A Metal Biosorber Candidate

Jurnal Biodjati, 2023
Metallothionein is a protein that is well known to play a role in metal metabolism in bacterial cells. Metallothionein is a multifunctional protein that has the potential to be used as a metal adsorbing agent.
Fajri Ikhsan, Ahmad Shulhany, Syarif Abdullah   +2 more
doaj   +1 more source

Downregulation of metallothionein-2 contributes to oxaliplatin-induced neuropathic pain

Journal of Neuroinflammation, 2021
Background We previously reported a correlation between small doses of oxaliplatin penetrating onto the spinal cord and acute pain after chemotherapy. Here, we propose that MT2 within the spinal dorsal horns participates in the development of oxaliplatin-
Xuelin Huang, Jie Deng, Ting Xu, Wenjun Xin, Yuehong Zhang, Xiangcai Ruan   +5 more
doaj   +1 more source

Metallothionein levels on the gill and liver of Mystus nigriceps (Valenciennes, 1840) in Welang River, Pasuruan City, East Java

Depik Jurnal, 2022
This research was conducted in October 2021 using a survey method. Sampling was carried out three times with a span of every 2 weeks at 3 stations along the lower reaches of the Welang River Pasuruan Regency.
Lisma Wardani, Endang Yuli Herawati, Asus Maizar Surya   +2 more
doaj   +1 more source

Relationship between Metallothionein and Mercury (Hg) in the Gill Tissue of the Barbonymus altus in the Brantas River Jombang, East Java

Journal of Experimental Life Science, 2023
Pollution of river waters is most often the result of human activities in managing agricultural land, industry, and transportation. The entry of pollutants such as heavy metal mercury (Hg) into the waters can interfere with the survival of fish waters ...
Aang Setyawan Anjasmara, Asus Maizar Suryanto Hertika, Uun Yanuhar   +2 more
doaj   +1 more source

Exacerbation of Elastase-Induced Emphysema via Increased Oxidative Stress in Metallothionein-Knockout Mice

Biomolecules, 2022
Although the pathogenesis of chronic obstructive pulmonary disease (COPD) is not yet fully understood, recent studies suggest that the disruption of the intracellular balance of oxidative (such as reactive oxygen species (ROS)) and antioxidant molecules ...
Ken Ichiro Tanaka, Sachie Shiota, Okina Sakakibara, Mikako Shimoda, Ayaka Takafuji, Misaki Takabatake, Yoshito Kadota, Takashige Kawakami, Shinya Suzuki, Masahiro Kawahara   +9 more
doaj   +1 more source

Metallothionein Expression and its Influence on the In Vitro Biological Behavior of Mucoepidermoid Carcinoma

Cells, 2020
Mucoepidermoid carcinoma (MEC) is the most common tumor in the salivary glands, often presenting with recurrence and metastasis due to its high invasive capacity.
João Rafael Habib Souza Aquime, Lara Carolina D’Araújo Pinto Zampieri, Maria Sueli da Silva Kataoka, Nelson Antonio Bailão Ribeiro, Ruy Gastaldoni Jaeger, Artur Luiz da Silva, Rommel Thiago Jucá Ramos, Sérgio de Melo Alves Júnior, João de Jesus Viana Pinheiro   +8 more
doaj   +1 more source

Metallothionein expression in feline injection site fibrosarcomas

BMC Veterinary Research, 2023
Background Feline injection site fibrosarcoma is an aggressive and infiltrative tumour arising in the background of chronic inflammation. The aim of this study was to evaluate the expression of metallothionein (I-II) in feline injection site ...
Mateusz Mikiewicz, Katarzyna Paździor-Czapula, Joanna Fiedorowicz, Michał Gesek, Iwona Otrocka-Domagała   +4 more
doaj   +1 more source

Evaluation of metallothionein response in Lymnaea stagnalis pond snail to exposured to trace metals and thiocarbamate fungicide

Біологічні студії, 2019
Pulmonate mollusks posses high uptake rates of dissolved metals and their bonding, mainly Cd, Zn and Cu by the metal-buffering protein, metallothionein (MT).
L. L. Gnatyshyna
doaj   +1 more source

METALLOTHIONEIN PADA HATI IKAN SEBAGAI BIOMARKER PENCEMARAN KADMIUM (Cd) DI PERAIRAN KALIGARANG SEMARANG (Metallothionein in The Fish Liver as Biomarker of Cadmium (Cd) Pollution in Kaligarang River Semarang)

Jurnal Manusia dan Lingkungan, 2015
ABSTRAK Penanda dini pencemaran kadmium  di sungai Kaligarang perlu diketahui sebagai alat monitoring pencemaran logam berat,  mengingat sungai Kaligarang digunakan untuk memenuhi kebutuhan air minum bagi masyarakat kota Semarang.
Nur Kusuma Dewi, Purwanto Purwanto, Henna Rya Sunoko   +2 more
doaj   +1 more source