Results 1 to 10 of about 75,382 (270)

Emerging Roles of Metallothioneins in Human Pathophysiology: A Review [PDF]

Health Science Reports
Background Metallothioneins (MTs) are small molecular‐weight proteins that either bind or release essential transition metals, depending on a specific cell situation.
Ousman Mohammed, Abdisa Tufa, Solomon Tebeje Gizaw   +2 more
doaj   +2 more sources

Metallothionein-protein interactions

Biomolecular Concepts, 2013
Metallothioneins (MTs) are a family of universal, small proteins, sharing a high cysteine content and an optimal capacity for metal ion coordination. They take part in a plethora of metal ion-related events (from detoxification to homeostasis, storage ...
Atrian Sílvia, Capdevila Mercè
doaj   +3 more sources

The transcriptional response of Caenorhabditis elegans to ivermectin exposure identifies novel genes involved in the response to reduced food intake [PDF]

, 2012
We have examined the transcriptional response of Caenorhabditis elegans following exposure to the anthelmintic drug ivermectin (IVM) using whole genome microarrays and real-time QPCR.
A Etter, A Fire, A Li, Al Ivens, BC Mullaney, BF Ardelli, CA Gonzalez, CC Mello, CE James, CI Bargmann, CL Edward, Clotilde K. Carlow, Debra J. Woods, DJ Brownlee, DJ Pemberton, DK Vassilatis, DM Yates, DW Huang, G Dennis Jr, IA Johnstone, IL Jonstone, J Kulas, J Wang, J Zheng, JA Dent, JA Dent, JH Freedman, John S. Gilleard, JS Gilleard, K Ashrafi, K Awadzi, K Reichert, KD Kimura, KT Jones, L Holden-Dye, LM Fox, M Kondoh, M Nakano, M Shinogi, MR Van Gilst, MY Osei-Atweneboana, N Custodia, N Sogawa, ND Sargison, NJ Szewczyk, O Hobert, PY Jeong, R Breitling, R Menzel, RJ Cousins, RM Kaplan, Roz Laing, S McCavera, Sai P. Ravikumar, ST Laing, Steven T. Laing, T Stiernagle, TS Churcher, Victoria Butler, Y Cui   +59 more
core   +14 more sources

Metallothionein Protein Modeling from Pseudomonas aeruginosa PAO1 as A Metal Biosorber Candidate

Jurnal Biodjati, 2023
Metallothionein is a protein that is well known to play a role in metal metabolism in bacterial cells. Metallothionein is a multifunctional protein that has the potential to be used as a metal adsorbing agent.
Fajri Ikhsan, Ahmad Shulhany, Syarif Abdullah   +2 more
doaj   +1 more source

Downregulation of metallothionein-2 contributes to oxaliplatin-induced neuropathic pain

Journal of Neuroinflammation, 2021
Background We previously reported a correlation between small doses of oxaliplatin penetrating onto the spinal cord and acute pain after chemotherapy. Here, we propose that MT2 within the spinal dorsal horns participates in the development of oxaliplatin-
Xuelin Huang, Jie Deng, Ting Xu, Wenjun Xin, Yuehong Zhang, Xiangcai Ruan   +5 more
doaj   +1 more source

Metallothionein levels on the gill and liver of Mystus nigriceps (Valenciennes, 1840) in Welang River, Pasuruan City, East Java

Depik Jurnal, 2022
This research was conducted in October 2021 using a survey method. Sampling was carried out three times with a span of every 2 weeks at 3 stations along the lower reaches of the Welang River Pasuruan Regency.
Lisma Wardani, Endang Yuli Herawati, Asus Maizar Surya   +2 more
doaj   +1 more source

Copper metallothioneins [PDF]

IUBMB Life, 2017
AbstractMetallothioneins (MTs) are a class of low molecular weight and cysteine‐rich metal binding proteins present in all the branches of the tree of life. MTs efficiently bind with high affinity several essential and toxic divalent and monovalent transition metals by forming characteristic polynuclear metal‐thiolate clusters within their structure ...
Jenifer, Calvo, Hunmin, Jung, Gabriele, Meloni   +2 more
openaire   +2 more sources

Bacterial metallothioneins [PDF]

Postępy Mikrobiologii - Advancements of Microbiology, 2017
Abstract Heavy metals are found in all living organisms where, as indispensable microelements (e.g. zinc, iron, copper), are involved in endless metabolic processes. However, living organisms are also at a risk of exposure to highly toxic metals, including cadmium or lead, which do not play any physiological role.
Agnieszka Mierek-Adamska, Wioleta Tylman-Mojżeszek, Zuzanna Znajewska, Grażyna B. Dąbrowska   +3 more
openaire   +2 more sources

Exacerbation of Elastase-Induced Emphysema via Increased Oxidative Stress in Metallothionein-Knockout Mice

Biomolecules, 2022
Although the pathogenesis of chronic obstructive pulmonary disease (COPD) is not yet fully understood, recent studies suggest that the disruption of the intracellular balance of oxidative (such as reactive oxygen species (ROS)) and antioxidant molecules ...
Ken Ichiro Tanaka, Sachie Shiota, Okina Sakakibara, Mikako Shimoda, Ayaka Takafuji, Misaki Takabatake, Yoshito Kadota, Takashige Kawakami, Shinya Suzuki, Masahiro Kawahara   +9 more
doaj   +1 more source

Relationship between Metallothionein and Mercury (Hg) in the Gill Tissue of the Barbonymus altus in the Brantas River Jombang, East Java

Journal of Experimental Life Science, 2023
Pollution of river waters is most often the result of human activities in managing agricultural land, industry, and transportation. The entry of pollutants such as heavy metal mercury (Hg) into the waters can interfere with the survival of fish waters ...
Aang Setyawan Anjasmara, Asus Maizar Suryanto Hertika, Uun Yanuhar   +2 more
doaj   +1 more source