Results 21 to 30 of about 63,819 (225)

Experimental study of metallothionein synthesis in modeling hyperthermic intraoperative intraperitoneal chemoperfusion with cysplatinum

Journal of Education, Health and Sport, 2018
In an experiment on white wild-type laboratory rats, it was shown that 90 minutes after intraperitoneal administration of cisplatin at a dose of 4 mg / kg as a solution heated to 43 °C, the integral level of metallothionein significantly increased in the
E. D. Pykhtieieva, E. G. Pykhtieieva, A. I. Gozhenko   +2 more
doaj   +3 more sources

Bacterium-Based Heavy Metal Biosorbents: Enhanced Uptake of Cadmium by E. coli Expressing a Metallothionein Fused to β-Galactosidase

BioTechniques, 2002
We investigated the potential utility of a recombinant E. coli that expresses the human metallothionein II gene as a fusion protein with β-galactosidase as a heavy metal biosorbent. E.
N. Yoshida, T. Kato, T. Yoshida, K. Ogawa, M. Yamashita, Y. Murooka   +5 more
doaj   +1 more source

AzuR From the SmtB/ArsR Family of Transcriptional Repressors Regulates Metallothionein in Anabaena sp. Strain PCC 7120

Frontiers in Microbiology, 2022
Metallothioneins (MTs) are cysteine-rich, metal-sequestering cytosolic proteins that play a key role in maintaining metal homeostasis and detoxification.
T. V. Divya, T. V. Divya, Celin Acharya, Celin Acharya   +3 more
doaj   +1 more source

Temporal variations in metallothionein concentration and subcellular distribution of metals in gills and digestive glands of the oyster Crassostrea angulata

Scientia Marina, 2010
The metallothionein levels and metal concentrations in whole body, digestive gland and gills of Crassostrea angulata were analyzed in field samples collected from the River Guadalquivir estuary over several years following a mining waste spill upstream ...
Chiara Trombini, Elena Fabbri, Julián Blasco   +2 more
doaj   +1 more source

Zinc Supplementation Dosage Variations to Metallothionein Protein Level of Rattus Norvegicus

International Journal of Science and Engineering, 2013
Zinc is an essential trace element involving in the activity of more than 300 enzymes and proteins of human body. One important role of zinc is to improve metallothionein protein binding heavy metals and functioning as heavy metal detoxification ...
Budi Santosa, Hertanto Wahyu Subagyo, Lisyani S, Henna Rya Sunoko   +3 more
doaj   +1 more source

Crambescin C1 Acts as A Possible Substrate of iNOS and eNOS Increasing Nitric Oxide Production and Inducing In Vivo Hypotensive Effect

Frontiers in Pharmacology, 2021
Crambescins are guanidine alkaloids from the sponge Crambe crambe. Crambescin C1 (CC) induces metallothionein genes and nitric oxide (NO) is one of the triggers.
Juan A. Rubiolo, Juan A. Rubiolo, Emilio Lence, Concepción González-Bello, María Roel, José Gil-Longo, Manuel Campos-Toimil, Manuel Campos-Toimil, Eva Ternon, Olivier P. Thomas, Antonio González-Cantalapiedra, Henar López-Alonso, Mercedes R. Vieytes, Luis M. Botana   +13 more
doaj   +1 more source

Immunohistochemistry with apoptotic-antiapoptotic proteins (p53, p21, bax, bcl-2), c-kit, telomerase, and metallothionein as a diagnostic aid in benign, borderline, and malignant serous and mucinous ovarian tumors

Diagnostic Pathology, 2012
Background In many tumors including ovarian cancer, cell proliferation and apoptosis are important in pathogenesis and there are many alterations in most of the genes related to the cell cycle.
Ozer Hatice, Yenicesu GoncaImir, Arici Sema, Cetin Meral, Tuncer Ersin, Cetin Ali   +5 more
doaj   +1 more source

Maternal zinc intakes and homeostatic adjustments during pregnancy and lactation. [PDF]

, 2012
Zinc plays critical roles during embryogenesis, fetal growth, and milk secretion, which increase the zinc need for pregnancy and lactation. Increased needs can be met by increasing the dietary zinc intake, along with making homeostatic adjustments in ...
Donangelo, Carmen, King, Janet
core   +2 more sources

Expression of biomarkers connected to endocrine disruption in Cottus gobio and Salmo trutta fario in relation to sewage treatment plant-efflux and pesticides

Frontiers in Environmental Science, 2022
The increasing efflux on a large scale of organic contaminants holding endocrine disrupting activity from sewage treatment plants produces detrimental biological effects to various fish species.
Michael Niederwanger, Josef Wieser, Melanie Thaler, Agnes Felber, Katja Schmölz, Wolfgang Mark, Erich Tasser, Rüdiger Kaufmann, Bernd Pelster   +8 more
doaj   +1 more source

Murine models of renal disease: Possibilities and problems in studies using mutant mice [PDF]

, 2000
The elucidation of the pathogenesis of human renal disease at the molecular level has been facilitated by the growing field of gene targeting and the development of mouse strains with single-gene deletions - the `knock-out' mice. Experimental nephrology,
Anders, Hans-Joachim, Schlöndorff, Detlef   +1 more
core   +1 more source