Results 21 to 30 of about 30,614 (220)
Frontiers in Microbiology, 2022 Metallothioneins (MTs) are cysteine-rich, metal-sequestering cytosolic proteins that play a key role in maintaining metal homeostasis and detoxification.
T. V. Divya +3 more
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Diagnostic Pathology, 2012 Background In many tumors including ovarian cancer, cell proliferation and apoptosis are important in pathogenesis and there are many alterations in most of the genes related to the cell cycle.
Ozer Hatice +5 more
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Zinc Supplementation Dosage Variations to Metallothionein Protein Level of Rattus Norvegicus
International Journal of Science and Engineering, 2013 Zinc is an essential trace element involving in the activity of more than 300 enzymes and proteins of human body. One important role of zinc is to improve metallothionein protein binding heavy metals and functioning as heavy metal detoxification ...
Budi Santosa +3 more
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Bacterial metallothioneins [PDF]
Postępy Mikrobiologii - Advancements of Microbiology, 2017 Abstract Heavy metals are found in all living organisms where, as indispensable microelements (e.g. zinc, iron, copper), are involved in endless metabolic processes. However, living organisms are also at a risk of exposure to highly toxic metals, including cadmium or lead, which do not play any physiological role.
Agnieszka Mierek-Adamska +3 more
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Frontiers in Pharmacology, 2021 Crambescins are guanidine alkaloids from the sponge Crambe crambe. Crambescin C1 (CC) induces metallothionein genes and nitric oxide (NO) is one of the triggers.
Juan A. Rubiolo +13 more
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The Evolution of Insect Metallothioneins [PDF]
Proceedings of the Royal Society B: Biological Sciences, 2020 ABSTRACTMetallothioneins (MTs) are a family of cysteine-rich metal-binding proteins that are important in the chelating and detoxification of toxic heavy metals. Until now, the short length and the low sequence complexity of MTs has hindered the possibility of any phylogenetic reconstruction, hampering the study of their evolution.
Haosu Cong +5 more
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Molecular Brain, 2010 Zinc dyshomeostasis has been recognized as an important mechanism for cell death in acute brain injury. An increase in the level of free or histochemically reactive zinc in astrocytes and neurons is considered one of the major causes of death of these ...
Lee Sook-Jeong, Koh Jae-Young
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The roles of metallothioneins in carcinogenesis [PDF]
Journal of Hematology & Oncology, 2018 Metallothioneins (MTs) are small cysteine-rich proteins that play important roles in metal homeostasis and protection against heavy metal toxicity, DNA damage, and oxidative stress. In humans, MTs have four main isoforms (MT1, MT2, MT3, and MT4) that are encoded by genes located on chromosome 16q13.
Jinghe Lang, Manfei Si
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The Regulation of Trace Metal Elements in Cancer Ferroptosis
Advanced Biology, EarlyView.The induction of ferroptosis inhibits tumor growth, enhances anticancer efficacy, and overcomes drug resistance. Recent evidence shows nonferrous metal elements play a role in ferroptosis. This review focuses on how trace metals regulate ferroptosis processes like iron accumulation, lipid peroxidation, and antioxidant defense.
Xiaoyan Wang +5 more
wiley +1 more source
Shapes of Differential Pulse Voltammograms and Level of Metallothionein at Different Animal Species
Sensors, 2007 Metallothioneins play a key role in maintaining homeostasis of essential metalsand in protecting of cells against metal toxicity as well as oxidative damaging.
Rene Kizek +5 more
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