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Early research on metallothionein centered on aspects related to a detoxification role. As our understanding of the complex endocrine control that regulates metallothionein gene expression increases, a wider appreciation of a functional role(s) is emerging.
M A, Dunn, T L, Blalock, R J, Cousins
openaire +2 more sources
A specific group of genes respond to cold dehydration stress in cut Alstroemeria flowers whereas ambient dehydration stress accelerates developmental senescence expression patterns [PDF]
Petal development and senescence entails a normally irreversible process. It starts with petal expansion and pigment production, and ends with nutrient remobilization and ultimately cell death.
Aharoni+75 more
core +2 more sources
Pulmonate mollusks posses high uptake rates of dissolved metals and their bonding, mainly Cd, Zn and Cu by the metal-buffering protein, metallothionein (MT).
L. L. Gnatyshyna
doaj +1 more source
Maternal zinc intakes and homeostatic adjustments during pregnancy and lactation. [PDF]
Zinc plays critical roles during embryogenesis, fetal growth, and milk secretion, which increase the zinc need for pregnancy and lactation. Increased needs can be met by increasing the dietary zinc intake, along with making homeostatic adjustments in ...
Donangelo, Carmen, King, Janet
core +2 more sources
Metallothionein: An overview [PDF]
Metallothioneins (MTs) were discovered in 1957 by Margoshes and Vallee and identified as low-molecular weight and sulphydryl rich proteins. It is not surprising that most mammalian tissues contain age related basal levels of MTs since they are involved in metalloregulatory processes that include cell growth and multiplication.
KT Manisenthil Kumar+4 more
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In an experiment on white wild-type laboratory rats, it was shown that 90 minutes after intraperitoneal administration of cisplatin at a dose of 4 mg / kg as a solution heated to 43 °C, the integral level of metallothionein significantly increased in the
E. D. Pykhtieieva+2 more
doaj +3 more sources
ABSTRAK Penanda dini pencemaran kadmium di sungai Kaligarang perlu diketahui sebagai alat monitoring pencemaran logam berat, mengingat sungai Kaligarang digunakan untuk memenuhi kebutuhan air minum bagi masyarakat kota Semarang.
Nur Kusuma Dewi+2 more
doaj +1 more source
Isolation and characterisation of metallothionein from the clam Ruditapes decussatus [PDF]
Metallothioneins (MT) were obtained after purification from metal-exposed clams (Ruditapes decussatus) using gel-permeation and ion-exchange chromatography.
Bebianno+42 more
core +2 more sources
We investigated the potential utility of a recombinant E. coli that expresses the human metallothionein II gene as a fusion protein with β-galactosidase as a heavy metal biosorbent. E.
N. Yoshida+5 more
doaj +1 more source
Cadmium (Cd2+) in the environment is a significant health hazard. Chronic low Cd2+ exposure mainly results from food and tobacco smoking and causes kidney damage, predominantly in the proximal tubule.
J. Fels+6 more
semanticscholar +1 more source