Results 51 to 60 of about 563,341 (187)

The determination of the concentrations of metamizol sodium in inflamed joints of pigs after intravenous and iontophoretic application [PDF]

open access: yesActa veterinaria, 2010
Concentrations of the NSAID metamizol sodium (MmNa) in the synovial fluid and hyaline cartilage of inflamed knee and elbow joints of pigs after i.v. application and iontophoresis (IPh) were investigated. The research was conducted on 14 male pigs divided equally into two experimental groups and exposed to artificial inflammation of knees and elbows ...
Đurđević, S.   +5 more
openaire   +2 more sources

Successful replacement of the urinary bladder following exteriorisation during bite‐induced scrotal trauma in a domestic rabbit (Oryctolagus cuniculus)

open access: yesVeterinary Record Case Reports, Volume 14, Issue 3, August 2026.
Abstract Scrotal exteriorisation of abdominal viscera is rarely reported in domestic rabbits and constitutes a surgical emergency. This report describes traumatic inguinoscrotal herniation of the urinary bladder in a domestic rabbit (Oryctolagus cuniculus), a 4‐month‐old entire male, following bite‐induced scrotal avulsion during territorial aggression.
Delcio Almeida Magalhães   +4 more
wiley   +1 more source

A case of chronic disseminated candidiasis in metamizole-induced neutropaenia [PDF]

open access: yes, 2022
Chronic disseminated candidiasis (CDC) is a severe complication of a disseminated yeast infection mainly seen after prolonged chemotherapy-induced neutropaenia in the context of haematological malignancy.
Stefan Zimmerli   +6 more
core   +2 more sources

Pathomechanism of Fever‐Induced Liver Failure in NBAS Deficiency and Treatment Effect of NAC—Observations In Vitro and In Vivo

open access: yesLiver International, Volume 46, Issue 8, August 2026.
ABSTRACT Background and Aims Pathogenic variants in neuroblastoma amplified sequence (NBAS) gene causes infantile liver failure type 2 (IFLS2; MIM 616483), characterised by recurrent episodes of liver failure triggered by febrile infections. The underlying pathophysiological mechanisms remain incompletely understood. With this work we try to shed light
Tian Sun   +29 more
wiley   +1 more source

The quantitative impact of metabolism‐inhibiting drugs on the occurrence of adverse drug reactions—A backward selection approach

open access: yesBritish Journal of Clinical Pharmacology, Volume 92, Issue 7, Page 2203-2211, July 2026.
Abstract Aim The quantitative effect of several inhibitory drugs on the development of adverse drug reactions (ADRs) is currently difficult to estimate. Our aim was to identify metabolic pathways, which, when inhibited, increase the risk for certain ADRs, and to use this system to consider comedication at individual level. Methods Data of a prospective
Judith Berres   +8 more
wiley   +1 more source

1-(5-ACETYL-3-METHYL-6-PHENYL-5H-[1,2,4]TRIAZOLO [3,4-b][1,3,4]THIADIAZIN-7-YL)-ETHANONE: DOSE-DEPENDENCE OF ANALGESIC EFFECT, LACK OF OPIOIDERGIC MECHANISM OF ACTION, EFFECT ON BEHAVIORAL REACTIONS AND ACUTE TOXICITY

open access: yesActa Medica Leopoliensia, 2023
Derivatives of 5,7-diacyl-3-H(alkyl)-6-aryl-5H-[1,2,4] triazolo[3,4-b][1,3,4]thiadiazine. Aim. To evaluate the dose dependence of the analgesic effect of the compound IFT_247, the participation of the opioidergic component in the mechanism of action ...
Andriy Koval, Sergiy Shtrygol
doaj   +1 more source

Postherpetic Neuralgia: Mechanisms, Risk Factors, and Stratified Management—A Narrative Review

open access: yesCNS Neuroscience &Therapeutics, Volume 32, Issue 7, July 2026.
The incidence of PHN is increasing, posing a substantial public health burden. Its pathogenesis involves VZV reactivation, peripheral and central sensitization, and genetic susceptibility, with key risk factors including older age, severe acute pain, extensive rash, immunocompromise, comorbidities, and delayed treatment.
Fei Tang, Fukun Zhao
wiley   +1 more source

Qualitative determination of sodium metamizole in pharmaceutical preparations [PDF]

open access: yes
Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu”, Chişinău, Republica MoldovaIntroducere. Metamizolul sodic este un analgezic puternic non-opioid utilizat pe scară largă în medicină.
Grinchevici, Igor
core   +1 more source

Growth and characterization of organic layers deposited on porous-patterned Si surface

open access: yesEPJ Web of Conferences, 2017
The organic layers with the thickness from a few nanometers up to few micrometers have been deposited from the chemical solution at room temperature on porous patterned Si surfaces using two medical solutions: thiamine diphosphide (pH=1÷2) and metamizole
Gorbach Tamara Ya.   +3 more
doaj   +1 more source

The Predictive Accuracy of Methods Commonly Used for Evaluating Animal Distress

open access: yesThe FASEB Journal, Volume 40, Issue 11, 15 June 2026.
Predictive accuracy of body weight change, distress score, burrowing, and nesting behavior across multiple intervention phases. ABSTRACT Accurate distress assessment is essential for ensuring animal welfare and scientific validity. Although behavioral and physiological indicators are commonly used, their predictive value across disease models and ...
Emily Leitner   +6 more
wiley   +1 more source

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