Results 61 to 70 of about 563,341 (187)

Effect of intravenous continual vs. Bolus doses of tramadol and metamizol sodium combination in acute pain management: Continual vs. Bolus doses of tramadol and metamizol combination: Pilot study [PDF]

open access: yesSerbian Journal of Anesthesia and Intensive Therapy, 2016
Introduction: Tramadol and metamizol are very commonly used postoperatively for acute pain (bolus doses). Combined iv infusion tramadol/metamizol provide safe and effective acute pain relief and there is no evidence for pharmacokinetic and pharmacodynamic side effects in clinical practice.
Jelena Jovičić   +6 more
openaire   +1 more source

Sodium Alginate–Chitosan Microcapsules: Release Profile and Viability of Encapsulated Bifidobacteria

open access: yesРегуляторные исследования и экспертиза лекарственных средств
INTRODUCTION. Oral administration of probiotics is limited by their low viability while passing through the harsh gastrointestinal environment. Microencapsulation in the alginate–chitosan system makes it possible to protect bifidobacterial cells and ...
P. A. Andryushkov   +2 more
doaj   +1 more source

Enhancing Preclinical Rigor: Evaluating Robustness and Numerical Stability in a Chronic Pancreatitis Mouse Model

open access: yesAnnals of the New York Academy of Sciences, Volume 1560, Issue 1, June 2026.
In a modified cerulein‐induced chronic pancreatitis (CP) mouse model, key hallmarks of CP were robustly induced in male and female C57BL/6J (BL6) and BALB/c mice, whereas cytokine responses varied partly according to strain and sex. The RORγt inhibitor GSK805 reduced Il23r expression in the BL6 strain, significantly decreased collagen I deposition and ...
Annika Thämlitz   +5 more
wiley   +1 more source

THE CHOICE OF DRUGS FOR THE TREATMENT OF INFECTIOUS DISEASES IN CHILDREN WITH DRUG ALLERGY

open access: yesДетские инфекции (Москва), 2018
The article presents the results of clinical observation of 104 children hospitalized in the infectious department and having manifestations of allergies to drugs (medicines) at the prehospital stage or in the hospital.
E. B. Pavlova   +6 more
doaj   +1 more source

Postoperative Pain Management After Lumbar Discectomy. A Systematic Review With Meta‐Analyses and Trial Sequential Analyses

open access: yesEuropean Journal of Pain, Volume 30, Issue 4, April 2026.
ABSTRACT Background Inadequate postoperative pain management after lumbar discectomy may delay recovery, increase the risk of chronic pain, and prolong hospitalization. Effective analgesic strategies must balance pain control with minimal adverse effects.
Josephine Zachodnik   +7 more
wiley   +1 more source

Developed Visible Spectrophotometric Analysis of Sodium Metamizole

open access: yes
The aim of this research was to exactly quantify pure sodium metamizole from tablets , using a spectrophotometric analysis in Visible range. The method applied has been subjected to a validation protocal which consisted in analyzing the following parameters: linearity of the method, detection limit (LD) , quantitation limit (LQ), Sandell's sensitivity,
Cristian-Catalin Gavat   +2 more
openaire   +1 more source

Impact of Thiazides and Fluoropyrimidines Interaction on Myelotoxicity and Other Adverse Events in Real‐World Practice: A Retrospective Cohort Study

open access: yesCancer Medicine, Volume 15, Issue 3, March 2026.
ABSTRACT Introduction The European Summary of Product Characteristics (SmPC) for 5‐FU warns of significant granulocyte decline when combined with thiazides, cyclophosphamide, or methotrexate, based on a 1981 cohort of 14 patients. Despite limited evidence, drug‐interaction checkers still flag this risk.
Gerard Ronda‐Roca   +5 more
wiley   +1 more source

The study of some promising pharmaceutical compositions with urease inhibitory activity for the tuberculosis reactivation prevention

open access: yesAnnals of Mechnikov's Institute, 2019
Introduction. The aim of the study was to study the ability to inhibit urease by some pharmaceutical compositions that are promising in the prevention of tuberculosis reactivation .
T Bomko, A Martynov, T Nosalskaya
doaj  

Experimental Study of Electrical Properties of Pharmaceutical Materials by Electrical Impedance Spectroscopy

open access: yesApplied Sciences, 2020
The physicochemical characterization of pharmaceutical materials is essential for drug discovery, development and evaluation, and for understanding and predicting their interaction with physiological systems.
Manuel Vázquez-Nambo   +6 more
doaj   +1 more source

Borna disease virus infection: Retrospective case series of five horses and two donkeys in Switzerland

open access: yesEquine Veterinary Education, Volume 38, Issue 3, Page e119-e129, March 2026.
Summary Borna disease is an acute to subacute, rarely chronic non‐purulent meningoencephaylomyelitis affecting mainly horses and sheep. This case series describes the clinical signs, diagnosis, treatment, outcome and post‐mortem findings of five horses and two donkeys with this condition. The equids affected were geldings or mares of various breeds and
I. L. Piotrowski, M. Hilbe, H. K. Junge
wiley   +1 more source

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