Results 31 to 40 of about 15,474 (218)

Human development II: We Need an Integrated Theory for Matter, Life and Consciousness to Understand Life and Healing

The Scientific World Journal, 2006
For almost a decade, we have experimented with supporting the philosophical development of severely ill patients to induce recovery and spontaneous healing.
Sören Ventegodt, Tyge Dahl Hermansen, Maj Lyck Nielsen, Birgitte Clausen, Joav Merrick   +4 more
doaj   +1 more source

Comparative transcriptomic analysis reveals gene regulation mediated by caspase activity in a chordate organism

BMC Molecular and Cell Biology, 2021
Background Apoptosis is a caspase regulated cell death present in all metazoans defined by a conserved set of morphological features. A well-described function of apoptosis is the removal of excessive cells during development and homeostasis.
Gabriel Krasovec, Anthi Karaiskou, Éric Quéinnec, Jean-Philippe Chambon   +3 more
doaj   +1 more source

Genome-Wide Analysis of MicroRNAs in Relation to Pupariation in Oriental Fruit Fly

Frontiers in Physiology, 2019
Insect metamorphosis is a complex process involving drastic morphological and physiological changes. microRNAs (miRNAs) are a class of endogenous small non-coding RNAs that play key roles in regulating various biological processes, including ...
Qiang Zhang, Qiang Zhang, Qiang Zhang, Qiang Zhang, Wei Dou, Wei Dou, Wei Dou, Wei Dou, Deng Pan, Deng Pan, Deng Pan, Deng Pan, Er-Hu Chen, Er-Hu Chen, Er-Hu Chen, Er-Hu Chen, Jin-Zhi Niu, Jin-Zhi Niu, Jin-Zhi Niu, Jin-Zhi Niu, Guy Smagghe, Guy Smagghe, Guy Smagghe, Guy Smagghe, Jin-Jun Wang, Jin-Jun Wang, Jin-Jun Wang, Jin-Jun Wang   +27 more
doaj   +1 more source

miRNAs of Aedes aegypti (Linnaeus 1762) conserved in six orders of the class Insecta

Scientific Reports, 2021
Aedes aegypti L. is the most important vector of arboviruses such as dengue, Zika, chikungunya, Mayaro, and yellow fever, which impact millions of people’s health per year.
Iram Pablo Rodríguez-Sanchez, Daniel Rafael Saldaña-Torres, Olga Karina Villanueva-Segura, Maria Lourdes Garza-Rodriguez, Mayra A. Gómez-Govea, Ghongwei Liang, María de Lourdes Ramírez-Ahuja, Margarita De La Luz Martinez-Fierro, Ivan Delgado-Enciso, Laura E. Martinez-de-Villarreal, Yu Zhou, Adriana E. Flores-Suarez, Xi Chen, Diana Resendez-Pérez, Chen-Yu Zhang, Gustavo Ponce-Garcia   +15 more
doaj   +1 more source

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

FEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon, Angéla Békesi, Latifa Kazzazy, Jázmin Mihály, Máté Varga, Beáta G. Vértessy, Kinga Nyíri   +6 more
wiley   +1 more source

Comparative transcriptomic analysis revealed dynamic changes of distinct classes of genes during development of the Manila clam (Ruditapes philippinarum)

BMC Genomics, 2022
Background The Manila clam Ruditapesphilippinarum is one of the most economically important marine shellfish. However, the molecular mechanisms of early development in Manila clams are largely unknown.
Yanming Zhang, Hongtao Nie, Zhihui Yin, Xiwu Yan   +3 more
doaj   +1 more source

Evaluation of the Dual Impact of Nanotechnologies on Health and Environment Through Alternative Bridging Models

Advanced Healthcare Materials, EarlyView.
This review explores how alternative invertebrate and small‐vertebrate models advance the evaluation of nanomaterials across medicine and environmental science. By bridging cellular and organismal levels, these models enable integrated assessment of toxicity, biodistribution, and therapeutic performance.
Marie Celine Lefevre, Margherita Bernardeschi, Matteo Battaglini, Gianni Ciofani   +3 more
wiley   +1 more source

Teleost fish metamorphosis under the influence of estrogenic hormones: targeting the thyroid axis – a literature review

Environment International
Estrogens, whether naturally excreted by humans and livestock or introduced through pharmaceuticals, are endocrine-disrupting chemicals (EDCs) with strong estrogenic activity.
Nathalie Leroux, Sébastien Baekelandt, Patrick Kestemont   +2 more
doaj   +1 more source

MicroRNA‐375‐3p Targets Fatty Acid Synthase and Relish to Regulate Energy Allocation During Pupal Metamorphosis and Starvation

Advanced Science, EarlyView.
During pupal metamorphosis and starvation, elevated 20‐hydroxyecdysone (20E) and suppressed insulin trigger Forkhead box O (FOXO) nuclear translocation, enhancing miR‐375‐3p expression. This downregulates fatty acid synthase (FASN) and Relish, promoting lipid breakdown for energy while prioritizing antioxidant responses over immune functions to support
Peng Chen, Meiqi Cheng, Jianhui Wang, Jing Tang, Xiaoqiao Huang, Yusi Li, Huiling Zhou, Ling Zhang, Yi Dong, Chengjun Li, Bin Li   +10 more
wiley   +1 more source

The presence of predators constrains larval development process by influencing critical developmental windows in the endangered Chinhai spiny newt

Ecology and Evolution
Predators significantly impact the development process and subsequently influence the metamorphic decisions of amphibian larvae. Larvae often exhibit induced growth and metamorphic plasticity in response to the presence of predators.
Xihong Zhu, Xia Qiu, Kaiyang Chen, Wei Li, Aichun Xu   +4 more
doaj   +1 more source