Results 61 to 70 of about 9,418 (266)

Enzyme and acid deconjugation of plasma sulfated metanephrines [PDF]

Clinica Chimica Acta, 2014
Total (i.e. free+sulfated) metanephrines in plasma is a biomarker for the diagnosis of pheochromocytoma/paraganglioma. Sulfated metanephrines must be completely deconjugated by perchloric acid hydrolysis or sulfatase treatment prior to analytical measurement to enable quantification by current techniques.
Melanie Glauser, Michael Metrailler, Sandrine Gerber‐Lemaire, Catherine Centeno, Caroline Seghezzi, M. Dunand, Karim Abid, Adeline Herren, Eric Grouzmann   +8 more
openalex   +5 more sources

Does cardiac resynchronization therapy restore peripheral circulatory homeostasis? [PDF]

, 2017
Aims: To evaluate whether peripheral circulatory ‘remodeling’ as measured by changes in vascular compliance and in markers of nitric oxide signaling contributes to patient response to cardiac resynchronization therapy (CRT)  Methods and results: Effects ...
Abraham, Abraham, Akar, Antoniades, Arrebola-Moreno, Balady, Bots, Brenyo, Bristow, Chirkov, Cleland, Enomoto, Fornwalt, Hayward, Heresztyn, Jiang, Kelly, Lang, Linde, Pitzalis, Procter, Ronden, Sahebkar, Santini, Schepers, Spindel, Tesselaar, Warriner, Yamawaki   +28 more
core   +1 more source

Sympathetic activity and early mobilization in patients in intensive and intermediate care with severe brain injuries: a preliminary prospective randomized study. [PDF]

, 2016
Patients who experience severe brain injuries are at risk of secondary brain damage, because of delayed vasospasm and edema. Traditionally, many of these patients are kept on prolonged bed rest in order to maintain adequate cerebral blood flow ...
Berney, L., Daniel, R.T., Diserens, K., Grouzmann, E., Hirt, L., Jöhr, J., Levivier, M., Luft, A.R., Pignat, J.M., Rocca, A., Van de Ville, D.   +10 more
core   +4 more sources

Fluorometric Determination of Urinary Metanephrine and Normetanephrine

Clinical Chemistry, 1964
Abstract A detailed procedure for the quantitative determination of metanephrine and normetanephrine is given. Epinephrine and norepinephrine are eliminated by selective adsorption on an alumina column. Metanephrine and normetanephrine are isolated with a cation-exchange resin.
S, BRUNJES, D, WYBENGA, V J, JOHNS
openaire   +2 more sources

Implementation of First‐Line Rapid Genome Sequencing for Children in Pediatric and Cardiac Intensive Care Units

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Substantial data supports the use of rapid exome and genome sequencing (rES/rGS) in Neonatal Intensive Care Units (NICU), but fewer studies have examined the impact of rES/rGS in other pediatric critical care units. We evaluated the impact on diagnostic yield and time to diagnosis following a single‐center hospital policy change allowing ...
Alexandra C. Keefe, Abbey A. Scott, Lukas Kruidenier, Jessie Conta, Darci L. Sternen, Sarah V. Clowes Candadai, Shannon M. Stasi, Julia Parish‐Morris, Megan Sikes, Margaret P. Adam, Anita E. Beck, Jennifer C. Hayek, Ian Glass, James T. Bennett, Ghayda Mirzaa, Paul Kruszka, Britt Johnson, Kirsty McWalter, Deborah Copenheaver, Bethany Friedman, Michael Bamshad, Katrina M. Dipple, Tara L. Wenger   +22 more
wiley   +1 more source

Seasonal and Climatic Influences on Catecholamine Metabolite Levels in Patients With and Without Pheochromocytoma–Paraganglioma [PDF]

Diagnostics (Basel)
Background/Objective: Pheochromocytomas and paragangliomas (PPGL) lead to marked catecholamine metabolite elevations, whereas the causes of mild increases remain unclear.
Fakı S, Tam A, Özdemir D, Demir P, Neşelioğlu S, Karaahmetli G, Altay F, Topaloğlu O, Ersoy R, Çakır B.   +9 more
europepmc   +2 more sources

Metabolomic and lipidomic signatures of Helicobacter pylori infection: Unveiling biochemical pathways associated with neurodegeneration

iMetaOmics, EarlyView.
Our study employed an integrated lipidomics and metabolomics approach to elucidate Helicobacter pylori‐driven metabolic perturbations along the gut–brain axis. H. pylori infection was established in gastric epithelial (AGS) cells, and the resulting conditioned media (secretome) was collected and exposed to neuronal (IMR‐32) cells.
Meenakshi Kandpal, Tarun Prakash Verma, Siddharth Singh, Hamendra Parmar, Hem Chandra Jha   +4 more
wiley   +1 more source

Reference intervals for plasma, urinary, and salivary concentrations of free metanephrines in dogs: Relevance to the diagnosis of pheochromocytoma

Journal of Veterinary Internal Medicine, 2023
Background Measurement of free metanephrines is recommended for screening of pheochromocytoma (PCC) but requires appropriate reference intervals (RIs).
Marit F. van denBerg, Hans S. Kooistra, Guy C. M. Grinwis, Sebastiaan A. vanNimwegen, Martijn vanFaassen, Ido P. Kema, Erik Teske, Sara Galac   +7 more
doaj   +1 more source

Lipid Profile in Primary Aldosteronism: Cross‐Sectional and Post‐Treatment Analyses

Lipids, EarlyView.
ABSTRACT The relationship between primary aldosteronism (PA) and lipid metabolism remains controversial, with inconsistent findings reported in the literature. This study aimed to clarify PA's impact on the lipid profile using both a cross‐sectional comparison with essential hypertension (EH) controls and a longitudinal within‐patient pre‐post ...
Meriem Yazidi, Arige Abid, Chayma Bel hadj Sliman, Elyes Kamoun, Ibtissem Oueslati, Fatma Chaker, Nadia Khessairi, Melika Chihaoui   +7 more
wiley   +1 more source

BSAVA Petsavers Article: Validation of an ELISA assay for measurement of the metabolite of serotonin, 5‐hydroxyindole acetic acid (5‐HIAA), in canine urine

Journal of Small Animal Practice, EarlyView.
Objectives Serotonin (5‐hydroxytryptophan), implicated in a number of canine diseases, has a very short half‐life in the serum. Urine concentration of its breakdown product 5‐hydroxyindole acetic acid after an 8 hour fast is a more reliable measure of circulating serotonin in humans.
D. Castillo, A. Swallow, T. Williams, P. Watson   +3 more
wiley   +1 more source