Results 141 to 150 of about 85,166 (274)
The Journal of Pathology, Volume 270, Issue 2, Page 241-254, October 2026.Abstract Reliable detection of structural variants (SVs) and copy number variations (CNVs) is crucial in the contemporary diagnostics of pediatric B‐cell acute lymphoblastic leukemia (B‐ALL). However, limitations of commonly used conventional and molecular cytogenetic methods may hinder the accurate genetic characterization of patients.
Anna Bekő +21 more
wiley +1 more source
Metaphase Chromosome Architecture
Cold Spring Harbor Symposia on Quantitative Biology, 1978 W, Wray +3 more
openaire +2 more sources
Graft Biology in the CRISPR Era: From Tissue Fusion to Genome Compatibility
Plant-Environment Interactions, Volume 7, Issue 5, October 2026.ABSTRACT Plant lineage has traditionally constrained grafting compatibility, with monocots generally considered incompatible because of their dispersed vascular bundles and limited secondary growth. Recent studies have shown that embryonic grafting can establish successful graft unions in selected monocot systems by exploiting early developmental ...
Melagani Subash Chandra Gowda Sahaja +5 more
wiley +1 more source
Cytogenetic Diversity of Variant Philadelphia Translocations in Chronic Myeloid Leukemia
International Journal of Laboratory Hematology, Volume 48, Issue 5, Page 1103-1112, October 2026.ABSTRACT Introduction Chronic myeloid leukemia (CML) is a disease characterized by Philadelphia (Ph) translocations. These translocations can be classical or variant. The structural features and diagnostic implications of variant Philadelphia translocations remain incompletely defined, and they display considerable cytogenetic heterogeneity. Methods In
Ayse Gul Bayrak Tokac +10 more
wiley +1 more source
New Phytologist, Volume 252, Issue 1, Page 178-191, October 2026.Characterization of periclinal and anticlinal cell divisions in dividing cambium stem cells (CSCs). (a) Scheme indicating periclinal and anticlinal cell divisions in CSCs in the Arabidopsis hypocotyl. The orange dashed ring in the middle panel represents the cambium area. The orange cuboids represent individual CSCs.
Xiaomin Liu +4 more
wiley +1 more source
New Phytologist, Volume 252, Issue 1, Page 145-162, October 2026.Long‐read whole‐genome sequencing revealed extensive chromosomal rearrangements and aneuploidy in a widely used Chlamydomonas reinhardtii stt7‐1 mutant. The STT7 gene (shown in red) was found to be split between two rearranged chromosomes, providing a molecular explanation for the long‐standing failure of this mutant in genetic crosses.
Sandrine Bujaldon +3 more
wiley +1 more source
Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs
FEBS Open Bio, Volume 16, Issue 9, Page 1691-1707, September 2026.Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner +7 more
wiley +1 more source
Developmental and Epileptic Encephalopathy due to Biallelic Pathogenic Variants in PIGM
Annals of Clinical and Translational Neurology, Volume 13, Issue 9, Page 1759-1771, September 2026.ABSTRACT Objective PIGM encodes a critical enzyme in the glycosylphosphatidylinositol (GPI)‐anchor biosynthesis pathway. While promoter‐region mutations in PIGM have been associated with a relatively mild phenotype characterized by portal vein thrombosis and absence seizures, recent evidence suggests that coding‐region mutations result in a more severe
Júlia Sala‐Coromina +11 more
wiley +1 more source
Dynamic Regulation of Endogenous Transcription Factor Hubs at Single‐Molecule Resolution
Advanced Science, Volume 13, Issue 52, 18 September 2026.This study combines single‐molecule microscopy and genome editing to characterize the dynamic behaviors of endogenous oncofusion transcription factor EWS::FLI1 in Ewing sarcoma cells. EWS::FLI1 forms neomorphic hubs that dynamically assemble and dissolve. The hubs are regulated during mitosis, by RNA, and by specific chemicals.
Shawn Yoshida +4 more
wiley +1 more source
A metaphase finder using single manufacturer's product
, 2012 Metaphase finder is a tool for biodosimetry that finds metaphase chromosomes among blood cells on slide glasses. It consists of microscope, auto-focus system, automated X-Y stage, camera and computer. It does the image diagnosis of the microscopic images
697902 +3 more
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