Results 121 to 130 of about 85,166 (274)

UK recommendations for Ki‐67 immunohistochemical staining and interpretation in breast cancer

Histopathology, EarlyView.
Where possible, a validated digital imaging system should be utilized. If this is not available, then intermediate scores (5%–30%) should be thoroughly assessed using the Ki‐67 International Working Group guidance. Difficult cases should be double scored.
Abeer M Shaaban, Andrew Dodson, Emad Rakha, Ian Ellis, Daniel Rea, Cecily Quinn, Elena Provenzano, Sarah Pinder, on behalf of the UK National Coordinating Committee for Breast Pathology (NCCBP), Association of Breast Pathology (ABP) and the UK National External Quality Assessment Scheme for Immunohistochemistry and In Situ Hybridisation (UK NEQAS ICC & ISH)   +9 more
wiley   +1 more source

ICSH Guidance on Bone Marrow Examination and Reporting

International Journal of Laboratory Hematology, EarlyView.
ABSTRACT Examination of the bone marrow (BM) remains fundamental to the diagnosis, classification, prognostication, and monitoring of hematolymphoid and other disorders affecting blood cell production. Since publication of the International Council for Standardization in Haematology (ICSH) guideline in 2008, advances in diagnostic technologies, disease
Wendy N. Erber, Alexandar Tzankov, Olga Pozdnyakova, Hiromichi Matsushita, Gina Zini, Leonie Saft, on behalf of the International Council for Standardization in Haematology   +6 more
wiley   +1 more source

Comparative Genomic Hybridization of Human Malignant Gliomas Reveals Multiple Amplification Sites and Nonrandom Chromosomal Gains and Losses [PDF]

, 1994
Nine human malignant gliomas (2 astrocytomas grade III and 7 glioblastomas) were analyzed using comparative genomic hybridization (CGH). In addition to the amplification of the EGFR gene at 7p12 in 4 of 9 cases, six new amplification sites were mapped to
Vogel, S., Ried, Thomas, Thiel, G., Manoir, Stanislas du, Meffert, M. C., Speicher, Michael R., Cremer, Thomas, Donis-Keller, Helen, Nürnberg, P., Lozonova, T., Jauch, Anna, Schröck, Evelin, Witkowski, R., Jänisch, W.   +13 more
core   +1 more source

Meeting in the middle before parting: metaphase normal [Mitosis movie series; 1]

, 2008
Presents metaphase PtK1 cell microinjected with X-rhodamine-labeled tubulin and Alexa 488-labeled CENP-F antibodies to fluorescently label kinetochore fibers (red) and kinetochores/spindle poles (green), respectively.
Cimini, Daniela, Cameron, Lisa A., Salmon, Edward D.   +2 more
core  

Mitotic metaphase and five different karyomorphs.

, 2012
Left row: mitotic metaphase; middle row: karyotypes; right row: idiograms of no.1 and no. 6. (a) Karyoype I obtained homomorphic biarmed chromosomes no. 1 (M/M) and no. 6 (m/m), the metaphase spread was taken from one male of Mt.
Xiaomao Zeng (129585), Yuchi Zheng (129581), Liyan Qing (129574), Yun Xia (129577)   +3 more
core   +1 more source

ATXR5 and ATXR6 restrict meiotic crossover formation within heterochromatin in Arabidopsis

Journal of Integrative Plant Biology, EarlyView.
The Arabidopsis H3K27 mono‐methyltransferases ATXR5 and ATXR6 repress crossovers within meiotic heterochromatin, are required for heterochromatin condensation and H3K27me1 establishment, and specifically influence the maintenance of DNA methylation in meiocytes.
Jun Zhang, Yue Yu, Han Wang, Meiling Li, Dingning Li, Chenjiang You, Yingxiang Wang, Cong Wang   +7 more
wiley   +1 more source

A robust biotechnology induces artificial genomic duplication via transient RNAi‐mediated suppression of OSD1 in rice

Journal of Integrative Plant Biology, EarlyView.
Plant Polyploidization via Gene Interference, a robust technology for inducing polyploidy in various rice accessions, uses transient RNAi‐mediated suppression of OSD1 to induce genomic duplication. Two strategies were used to directly induce fertile autotetraploid plants in the first generation, thereby substantially shortening the breeding cycle ...
Zijun Lu, Lianjun Zhu, Guobin Liang, Rou Chen, Yu Huang, Jia Yang, Liang Fu, Xiangxing Zhao, Runze Wu, Xiangdong Liu   +9 more
wiley   +1 more source

Meeting in the middle before parting: metaphase normal [Mitosis movie series; 1]

, 2014
Presents metaphase PtK1 cell microinjected with X-rhodamine-labeled tubulin and Alexa 488-labeled CENP-F antibodies to fluorescently label kinetochore fibers (red) and kinetochores/spindle poles (green), respectively.
Cimini, Daniela, Cameron, Lisa A., Salmon, Edward D.   +2 more
core  

Ultrastructure of Metaphase II Centromeres

, 2013
(A–F) Six serial sections of a metaphase II centromere. Conventional technique. The outer plates of both sister kinetochores (arrowheads) are clearly differentiated.(G and H) Two sections of metaphase II centromeres after the Os-PPD technique.
Adela Calvente (17273), José A Suja (17276), Linda Wordeman (17274), María Teresa Parra (17269), Jesús Page (17272), Alberto Viera (17271), Rocío Gómez (17270), Julio S Rufas (17275)   +7 more
core   +1 more source

The MacBrain Resource Center (MBRC) rhesus macaque embryonic brain histology datasets

Journal of Anatomy, EarlyView.
We introduce the MacBrain Resource Center (MBRC) Collections of rhesus macaque embryonic brain tissue. Here, we illustrate histo‐ and immunohistology from our dynamically growing Collection 6, which currently contains >10,000 zoomable and downloadable images from n = 14 male and female embryos from early to late in gestation.
Valeria Mendoza‐Silva, Emma Burke, Lucy Greene, Mikhail Rodov, Janja Kopić, Phil Barello, Yury M. Morozov, Keiko Moriya‐Ito, Chiaki Ohtaka‐Maruyama, Zeljka Krsnik, Pasko Rakic, Alvaro Duque   +11 more
wiley   +1 more source