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Repurposed hnRNPC binds mature mRNAs and safeguards the mitotic transcriptome. [PDF]
Nucleic Acids ResLev-Ari L +5 more
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Lgl antagonizes Par complex membrane association to enable neural stem cell asymmetric division. [PDF]
J Cell SciWelch SE, LaFoya B, Prehoda KE.
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Evolution and the meaning of metaphase*
Journal of Cell Science, 1992ABSTRACT We used an evolutionary test to ask whether the congression of chromosomes to the spindle equator is important in itself or just a mitotic happenstance. If congression matters, then it might evolve if absent initially. Previous workers established that newly made trivalents, meiotic units of three chromosomes, generally do not ...
R B, Nicklas, P, Arana
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Immunoelectronmicroscopy of metaphase chromosomes
Histochemistry, 1982A method for the preparation of ultrathin sections of metaphase chromosomes is described. This method was applied to human metaphase chromosomes, which were immunocytochemically stained with anti-DNA and anti-ribonucleoprotein antibodies, derived from patients with auto-immune disease. Conventionally prepared metaphase spreads as well as cytocentrifuge
F T, Bosman, P K, Nakane
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Nature, 1971
OSTERGREN1 suggested that, before and during metaphase, the mitotic and meiotic chromosomes are subjected to pole-directed forces α, which orient the chromosomes at the equator of the spindle and separate them at anaphase. He also postulated a centrifugal force, γ, moving the chromosomes to the periphery of the metaphase plate; but he could suggest no ...
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OSTERGREN1 suggested that, before and during metaphase, the mitotic and meiotic chromosomes are subjected to pole-directed forces α, which orient the chromosomes at the equator of the spindle and separate them at anaphase. He also postulated a centrifugal force, γ, moving the chromosomes to the periphery of the metaphase plate; but he could suggest no ...
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The Physics of the Metaphase Spindle
Annual Review of Biophysics, 2018The assembly of the mitotic spindle and the subsequent segregation of sister chromatids are based on the self-organized action of microtubule filaments, motor proteins, and other microtubule-associated proteins, which constitute the fundamental force-generating elements in the system.
Oriola, D., Needleman, D., Brugués, J.
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1995
Usually, oocyte meiosis reinitiation appears as a two step process during which release from the prophase block is followed by a second arrest in metaphase I or II. In this review, we will examine the mechanisms required to maintain the metaphase arrest and stabilize MPF activity at this stage.
P, Colas, P, Guerrier
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Usually, oocyte meiosis reinitiation appears as a two step process during which release from the prophase block is followed by a second arrest in metaphase I or II. In this review, we will examine the mechanisms required to maintain the metaphase arrest and stabilize MPF activity at this stage.
P, Colas, P, Guerrier
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Journey of oocyte from metaphase‐I to metaphase‐II stage in mammals
Journal of Cellular Physiology, 2018In mammals, journey from metaphase‐I (M‐I) to metaphase‐II (M‐II) is important since oocyte extrude first polar body (PB‐I) and gets converted into haploid gamete. The molecular and cellular changes associated with meiotic cell cycle progression from M‐I to M‐II stage and extrusion of PB‐I remain ill understood.
Alka, Sharma +5 more
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Reproductive BioMedicine Online, 2002
Since its advent in 1974, at least 11 methods have been developed to introduce potentially heritable exogenous DNA (transgenes; tgs) into mammals. These methods are now briefly reviewed in the context of a nascent method that has been demonstrated by microinjection of membrane-depleted sperm heads and tg DNA into metaphase II (mII) oocytes: mII ...
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Since its advent in 1974, at least 11 methods have been developed to introduce potentially heritable exogenous DNA (transgenes; tgs) into mammals. These methods are now briefly reviewed in the context of a nascent method that has been demonstrated by microinjection of membrane-depleted sperm heads and tg DNA into metaphase II (mII) oocytes: mII ...
openaire +2 more sources