Results 61 to 70 of about 85,166 (274)
Cohesin and condensin extrude DNA loops in a cell cycle-dependent manner
eLife, 2020 Loop extrusion by structural maintenance of chromosomes (SMC) complexes has been proposed as a mechanism to organize chromatin in interphase and metaphase. However, the requirements for chromatin organization in these cell cycle phases are different, and
Stefan Golfier +3 more
doaj +1 more source
Paraformaldehyde Fixation May Lead to Misinterpretation of the Subcellular Localization of Plant High Mobility Group Box Proteins. [PDF]
PLoS ONE, 2015 Arabidopsis High Mobility Group Box (HMBG) proteins were previously found associated with the interphase chromatin but not the metaphase chromosome.
Man-Wah Li, Liang Zhou, Hon-Ming Lam
doaj +1 more source
Assembly and Maintenance of Myofibrils in the Heart
Cytoskeleton, EarlyView.ABSTRACT The assembly of actin and myosin to the paracrystalline arrangement of myofibrils in striated muscle, that is, heart and skeletal, has puzzled many a cell biologist. Different models, based on cultured cardiomyocytes, were proposed for the last 30 years to explain the sequence of events.
Elisabeth Ehler
wiley +1 more source
Towards automated metaphase cell detection using foundation models: A SAM and DINO-based approach
Engineering Science and Technology, an International JournalKaryotyping is a widely used laboratory technique to detect abnormalities in chromosomes. Karyotyping consists of many steps, including collecting samples, cell culturing and metaphase cell detection.
M. Cihad Arslanoglu +2 more
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Cytoskeleton, EarlyView.ABSTRACT Few proteins have inspired as much curiosity as kinesin. Since its discovery 40 years ago, kinesin has become one of the best understood molecular machines in biology, yet it continues to reveal new questions about how cells organize and move their contents.
Ronald D. Vale
wiley +1 more source
Optimizing chromosome dispersion quality: the key role of cell density
Frontiers in Cell and Developmental BiologyObjectiveThis study aims to optimize metaphase dispersion in automated detection by quantitatively determining the optimal cell suspension density to enhance the accuracy and efficiency of chromosomal aberrations analysis.MethodsLymphocyte metaphase ...
Chao-Xian Gao +6 more
doaj +1 more source
Fimbrin phosphorylation by metaphase Cdk1 regulates actin cable dynamics in budding yeast
Nature Communications, 2016 Metaphase cells preferentially promote actin cable assembly through cyclin-dependent kinase 1 (Cdk1) activity. Here the authors identify fimbrin as one of the main metaphase Cdk1 targets for cell cycle regulation of actin cable assembly in budding yeast.
Yansong Miao +6 more
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مجلة مركز بحوث التقنيات الاحيائية, 2009 This study deals with the cytogenetic effect of lactobacillus acidophilus concentrated filtrate on metaphase index of bone marrow cells in mice. Cyclophosphamide is a drug that is used primarily for treating several types of cancer.
Ebtehal H. Al-Naimie +2 more
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Developmental Dynamics, EarlyView.Abstract Background The promoters and enhancers of heat shock genes, such as the 1.5‐kb promoter of the zebrafish hsp70l gene, are valuable tools for temporal activation of transgenes. It has been widely purported that heat shock treatments result in ubiquitous expression of hsp70l‐driven transgenes.
Jong‐Su Park, Xiangyun Wei
wiley +1 more source
Detection of chromosome aberrations in metaphase and interphase tumor cells by in situ hybridization using chromosome-specific library probes [PDF]
, 1988 Chromosome aberrations in two glioma cell lines were analyzed using biotinylated DNA library probes that specifically decorate chromosomes 1, 4, 7, 18 and 22 from pter to qter.
Cremer, Thomas +4 more
core +1 more source