Results 91 to 100 of about 5,355 (193)

An Integrated Pipeline for Annotation and Visualization of Metagenomic Contigs

Frontiers in Genetics, 2019
Here, we describe MetaErg, a standalone and fully automated metagenome and metaproteome annotation pipeline. Annotation of metagenomes is challenging. First, metagenomes contain sequence data of many organisms from all domains of life.
Xiaoli Dong, Marc Strous
doaj   +1 more source

Quantitative metaproteomics of medieval dental calculus reveals individual oral health status [PDF]

, 2018
The composition of ancient oral microbiomes has recently become accessible owing to advanced biomolecular methods such as metagenomics and metaproteomics, but the utility of metaproteomics for such analyses is less explored.
Olsen, Jesper V, Lanigan, Liam T, Cappellini, Enrico, Jensen, Lars J, Daniel Belstrøm, Willerslev, Eske, Niels Lynnerup, Lars J. Jensen, Kelstrup, Christian D, Fotakis, Anna K, David Lyon, Mackie, Meaghan, Jersie-Christensen, Rosa R, Liam T. Lanigan, Rosa R. Jersie-Christensen, Meaghan Mackie, Eske Willerslev, Lynnerup, Niels, Lyon, David, Belstrøm, Daniel, Christian D. Kelstrup, Anna K. Fotakis, Jesper V. Olsen, Enrico Cappellini   +23 more
core   +1 more source

Enhanced Growth and Activities of the Dominant Functional Microbiota of Chicken Manure Composts in the Presence of Maize Straw

Frontiers in Microbiology, 2018
As a consequence of intensive feeding, the bulk deposition of livestock manure causes severe environmental problems. Composting is a promising method for waste disposal, and the fermentation process is driven by microbial communities.
Lili Zhang, Lili Zhang, Lijuan Li, Xiaoguang Pan, Zelu Shi, Xihong Feng, Bin Gong, Jian Li, Lushan Wang   +8 more
doaj   +1 more source

Multi-Omic Biogeography of the Gastrointestinal Microbiota of a Pre-Weaned Lamb

Proteomes, 2017
The digestive functions of the pre-weaned lamb gastrointestinal tracts (GITs) have been the subject of much research in recent years, but the microbial and host functions underlying these complex processes remain largely unknown.
Antonio Palomba, Alessandro Tanca, Cristina Fraumene, Marcello Abbondio, Francesco Fancello, Alberto Stanislao Atzori, Sergio Uzzau   +6 more
doaj   +1 more source

Evaluating Metagenomic Prediction of the Metaproteome in a 4.5-Year Study of a Patient with Crohn's Disease

mSystems, 2019
Although genetic approaches are the standard in microbiome analysis, proteome-level information is largely absent. This discrepancy warrants a better understanding of the relationship between gene copy number and protein abundance, as this is crucial ...
Robert H. Mills, Yoshiki Vázquez-Baeza, Qiyun Zhu, Lingjing Jiang, James Gaffney, Greg Humphrey, Larry Smarr, Rob Knight, David J. Gonzalez   +8 more
doaj   +1 more source

Characterization of ML-005, a Novel Metaproteomics-Derived Esterase

Frontiers in Microbiology, 2018
A novel gene encoding for a lipolytic enzyme, designated ML-005, was recently identified using a functional metaproteomics approach. We heterologously expressed this protein in Escherichia coli and biochemically characterized it.
Premankur Sukul, Natalie Lupilov, Lars I. Leichert   +2 more
doaj   +1 more source

Metaproteomics for the functional analysis of microbiomes: recent achievements & prospects

, 2023
International audienceMicroorganisms play a major role in human, animal and vegetal health, as well as in key terrestrial geochemical processes. To understand how microbial communities function, how they interact with the host and the risks of dysbiosis,
Armengaud, Jean
core   +1 more source

An integrated metaproteomics workflow for studying host-microbe dynamics in bronchoalveolar lavage samples applied to cystic fibrosis disease

mSystems
Airway microbiota are known to contribute to lung diseases, such as cystic fibrosis (CF), but their contributions to pathogenesis are still unclear. To improve our understanding of host-microbe interactions, we have developed an integrated analytical and
Monica E. Kruk, Subina Mehta, Kevin Murray, LeeAnn Higgins, Katherine Do, James E. Johnson, Reid Wagner, Chris H. Wendt, John B. O’Connor, J. Kirk Harris, Theresa A. Laguna, Pratik D. Jagtap, Timothy J. Griffin   +12 more
doaj   +1 more source

Posttranslational modifications: an emerging functional layer of diet-host-microbe interactions

mBio
The microbiome plays a vital role in human health, with changes in its composition impacting various aspects of the body. Posttranslational modification (PTM) regulates protein activity by attaching chemical groups to amino acids in an enzymatic or non ...
Lirit Duchovni, Genrieta Shmunis, Lior Lobel   +2 more
doaj   +1 more source

Abstracts

Molecular Oncology, Volume 20, Issue S1, Page 1-692, August 2026.
Abstracts submitted to the ‘EACR 2026 Congress: Innovative Cancer Science’, from 08–11 June 2026 and accepted by the Congress Organising Committee are published in this Supplement of Molecular Oncology, an affiliated journal of the European Association for Cancer Research (EACR).
wiley   +1 more source