Results 81 to 90 of about 5,355 (193)

Benchmarking low- and high-throughput protein cleanup and digestion methods for human fecal metaproteomics

mSystems
The application of fecal metaproteomics to large-scale studies of the gut microbiota requires high-throughput analysis and standardized experimental protocols.
Alessandro Tanca, Maria Antonietta Deledda, Laura De Diego, Marcello Abbondio, Sergio Uzzau   +4 more
doaj   +1 more source

Microbial Signals in Cancer: Dissecting Host–Microbiota–Tumor Interactions and Potential Therapeutic Strategy

MedComm, Volume 7, Issue 9, September 2026.
Microbial signals from gut and tumor‐resident bacteria, fungi, viruses, and bacteriophages reshape immune and metabolic networks within the tumor microenvironment, thereby influencing cancer progression, treatment response. Therapeutic modulations, including dietary interventions, probiotics, antibiotics, fecal microbiota transplantation, engineered ...
Juan Lu, Mengjuan Xuan, Liang Yu, Zhongyang Xie, Qingfei Chu, Shihui Wei, Tuokai Wang, Chen Xue, Lanjuan Li   +8 more
wiley   +1 more source

Metaproteomics reveals age-specific alterations of gut microbiome in hamsters with SARS-CoV-2 infection

Gut Microbes
The gut microbiome’s pivotal role in health and disease is well established. SARS-CoV-2 infection often causes gastrointestinal symptoms and is associated with changes of the microbiome in both human and animal studies.
Marybeth Creskey, Fabiola Silva Angulo, Qing Wu, Levi Tamming, Emily E. F. Fekete, Kai Cheng, Zhibin Ning, Angela Wang, Patrícia Brito Rodrigues, Vinícius de Rezende Rodovalho, Marco Aurélio Ramirez Vinolo, Daniel Figeys, Xuguang Li, Francois Trottein, Xu Zhang   +14 more
doaj   +1 more source

Clostridial Butyrate Biosynthesis Enzymes Are Significantly Depleted in the Gut Microbiota of Nonobese Diabetic Mice

mSphere, 2018
Increasing evidence suggests that the intestinal microbiota is involved in the pathogenesis of type 1 diabetes (T1D). Here we sought to determine which gut microbial taxa and functions vary between nonobese diabetic (NOD) mice and genetically modified ...
Alessandro Tanca, Antonio Palomba, Cristina Fraumene, Valeria Manghina, Michael Silverman, Sergio Uzzau   +5 more
doaj   +1 more source

Differential Expression of Human and Bacterial Proteins Reveals Microbiome–Host Crosstalk in Metabolic Disorders

PROTEOMICS – Clinical Applications, Volume 20, Issue 5, September 2026.
ABSTRACT Purpose The growing prevalence of obesity, MetS, and T2DM highlights the need to better understand host–microbiota interactions. While gut microbiota has been widely investigated, interactions between the oral microbiota and human salivary proteins remain largely unexplored.
Carlos Vinicius Ferreira da Silva, Carlos José Ferreira da Silva, Fernanda da Silva Marinho, Youssef Bacila Sade, Sandra Mara Naressi Scapin, Fabiano L. Thompson, Cristiane Thompson, Eidy de Oliveira Santos   +7 more
wiley   +1 more source

Metaproteomics to investigate the response of the biomass of a membrane bioreactor to a decrease of organic supply

, 2017
Bacteria of activated sludge for wastewater treatment degrade and oxidize the polluting matter. They can also select and adapt to metabolize complex substrates.
Giovanni Berardi, Alfieri Pollice, Giuseppe Laera, Carlo Salerno   +3 more
core  

Challenges and perspectives of metaproteomic data analysis

Journal of Biotechnology, 2017
In nature microorganisms live in complex microbial communities. Comprehensive taxonomic and functional knowledge about microbial communities supports medical and technical application such as fecal diagnostics as well as operation of biogas plants or waste water treatment plants.
Heyer, R., Schallert, K., Zoun, R., Becher, B., Saake, G., Benndorf, D.   +5 more
openaire   +3 more sources

Soil Metaproteomics for Microbial Community Profiling: Methodologies and Challenges [PDF]

peer reviewedSoil represents a complex and dynamic ecosystem, hosting a myriad of microorganisms that coexist and play vital roles in nutrient cycling and organic matter transformation.
Pan, Haixia, Gillan, David, Wattiez, Ruddy   +2 more
core   +2 more sources

Proposal of a decoy-free FDR approach suitable for metaproteomics.

, 2021
International audienceAccurate and fast evaluation of the False Discovery Rate (FDR) of spectra-to-peptide sequences inference is a difficult task in Metaproteomics, because the extra-large databases used are often largely incomplete and include numerous
Jouffret, Virginie, Pible, Olivier, Culotta, Karen, Armengaud, Jean   +3 more
core   +1 more source

Exploring the functional diversity and metabolic activities of the human gut microbiome in Thai adults in response to a prebiotic diet

Microbiology Spectrum
Exploring dietary methods to alter microbial communities and metabolic functions is becoming an increasingly fascinating strategy for improving health. Copra meal hydrolysate (CMH) is alternatively used as a gut health supplement. However, the functional
Amornthep Kingkaw, Preecha Patumcharoenpol, Narissara Suratannon, Massalin Nakphaichit, Sittiruk Roytrakul, Wanwipa Vongsangnak   +5 more
doaj   +1 more source