Results 61 to 70 of about 5,355 (193)

Multi‐omics–driven precision medicine

iMeta, EarlyView.
Multi‐omics‐driven precision medicine (MODPM) provides a multiscale, continuously learnable framework that integrates genomics, epigenomics, transcriptomics, proteomics, metabolomics, microbiome profiles, and clinical data. Powered by artificial intelligence and foundation models, MODPM enables cross‐modal representation learning, contextual modeling ...
Huibo Li, Zhe Zhao, Yifan Zhang, Yao Ma, Gaofei Hu, Min Zeng, Zhanqun Yang, Zixuan Zhao, Xin Zhou, Wei Hu, Yuxuan Sun, Meng Su, Jun Li, Matthew Whiteman, Wei Fu, Chao Zhong, Lemin Zheng, Long Chen, Hairong Lv, Rongsheng Zhao, Yi Zhun Zhu   +20 more
wiley   +1 more source

The Microbiome as a Mirror: Distinguishing Healthy Individuals From Chronic Constipated Patients and Identifying Those With Hidden Psychiatric Burden

Microbiota Medicine Research, EarlyView.
Gut microbiota signatures distinguish chronic constipated patients from healthy individuals, supporting noninvasive diagnostic potential. Despite challenges in identifying psychiatric‐related comorbidities, microbial alterations, particularly in neurotransmitter and inflammatory pathways, lay the groundwork for future companion diagnostics and ...
Hongyan Qi, Ting Yu, Weichen Liu, Ya Jiang, Die Chen, Li Gao, Hui Li, Yurong Tang   +7 more
wiley   +1 more source

Metaproteomic analysis of atmospheric aerosol samples [PDF]

Analytical and Bioanalytical Chemistry, 2016
Metaproteomic analysis of air particulate matter provides information about the abundance and properties of bioaerosols in the atmosphere and their influence on climate and public health. We developed and applied efficient methods for the extraction and analysis of proteins from glass fiber filter samples of total, coarse, and fine particulate matter ...
Liu, F., Lai, S., Reinmuth-Selzle, K., Scheel, J., Fröhlich-Nowoisky, J., Despres, V., Hoffmann, T., Pöschl, U., Kampf, C.   +8 more
openaire   +3 more sources

More Is Not Always Better: Evaluation of 1D and 2D-LC-MS/MS Methods for Metaproteomics

Frontiers in Microbiology, 2019
Metaproteomics, the study of protein expression in microbial communities, is a versatile tool for environmental microbiology. Achieving sufficiently high metaproteome coverage to obtain a comprehensive picture of the activities and interactions in ...
Tjorven Hinzke, Tjorven Hinzke, Tjorven Hinzke, Angela Kouris, Rebecca-Ayme Hughes, Marc Strous, Manuel Kleiner, Manuel Kleiner   +7 more
doaj   +1 more source

Gut Microbiota of Gray Snub‐Nosed Monkeys: Adaptation to Seasonal Variations Through Energy Compensation and Thermogenesis

Integrative Zoology, EarlyView.
Based on metagenome‐assembled genomes (MAGs), the gut microbiota of the gray snub‐nosed monkeys recovered 1229 non‐redundant MAGs. The gut microbiota showed an enhanced capacity to produce energy substrates with increased conversion activity of these substrates during winter.
Yue Sun, Mingyi Zhang, Xiaochen Wang, Xiaolong Huang, Yanze Yu, Huijuan Pan, Haibo Li, Lei Shi, Wei Yang, Chen Zhang, Bo Ding, Xun Liu, Jianfeng Li, Changjiang Qian, Boxing Cheng, Chao Zhang, Jingcheng Ran, Ming Li   +17 more
wiley   +1 more source

Genome-Resolved Metaproteomic Analysis of Microbiota and Metabolic Pathways Involved in Taste Formation During Chinese Traditional Fish Sauce (Yu-lu) Fermentation

Frontiers in Nutrition, 2022
Complex microbial metabolism is key to taste formation in high-quality fish sauce during fermentation. To guide quality supervision and targeted regulation, we analyzed the function of microbial flora during fermentation based on a previously developed ...
Yueqi Wang, Yueqi Wang, Yueqi Wang, Yanyan Wu, Yanyan Wu, Yanyan Wu, Chunsheng Li, Chunsheng Li, Chunsheng Li, Yongqiang Zhao, Yongqiang Zhao, Yongqiang Zhao, Huan Xiang, Laihao Li, Laihao Li, Laihao Li, Xianqing Yang, Xianqing Yang, Xianqing Yang, Shengjun Chen, Shengjun Chen, Shengjun Chen, Leilei Sun, Bo Qi, Bo Qi, Bo Qi   +25 more
doaj   +1 more source

Microbiota Signatures in Early Life and Their Association With Food Allergy: A Systematic Review

Allergy, EarlyView.
ABSTRACT Food allergy (FA) is increasing worldwide, and early life may be a critical window for immune training. We systematically reviewed observational human studies linking early‐life microbiota (infant, maternal, environmental, or extraintestinal) profiled using culture‐based and/or culture‐independent methods (including sequencing‐based approaches)
Eduard Flores Ventura, Jeremy Corriger, Hélène Omer, Marie Bodinier, Dirk Haller, Tomer Hertz, Martin Larsen, Maria Carmen Collado   +7 more
wiley   +1 more source

Can Artificial Intelligence Be Utilised to Develop Point‐of‐Care Endodontic Microbiological Technologies?

International Endodontic Journal, EarlyView.
ABSTRACT Background Primary or persistent endodontic disease is caused by microbial biofilms that irritate the pulp and periapical tissues. Extensive microbiological analyses of these biofilms and their constituent pathogens have revealed their diversity and complexity.
Ashraf F. Fouad
wiley   +1 more source

Wolan/Su Lab Metaproteomics repo snapshot

, 2015
<p>Snapshot of Wolan / Su Lab metaproteomics git repository<br />  </p> <p>Up-to-date version should be available at http://bitbucket.org/sulab/metaproteomics</p ...
Chatterjee, Sandip, Stupp, Greg (5304142), Chatterjee, Sandip (5246731), Stupp, Greg   +3 more
core   +1 more source

Metaproteomic characterization of Vitis vinifera rhizosphere

FEMS Microbiology Ecology, 2018
The rhizosphere is a hotspot of microbial activity where the release of root exudates stimulates bacterial density and diversity. The majority of the bacterial cells in soil are viable, unculturable, but active. Proteomic tools could be useful in gaining information about microbial community activity and to better understand the real interactions ...
E. Bona, N. Massa, G. Novello, L. Boatti, P. Cesaro, V. Todeschini, V. Magnelli, M. Manfredi, E. Marengo, F. Mignone, G. Berta, G. Lingua, E. Gamalero   +12 more
openaire   +3 more sources