Results 31 to 40 of about 4,824 (200)
MetaLP: An integrative linear programming method for protein inference in metaproteomics.
PLoS Computational Biology, 2022 Metaproteomics based on high-throughput tandem mass spectrometry (MS/MS) plays a crucial role in characterizing microbiome functions. The acquired MS/MS data is searched against a protein sequence database to identify peptides, which are then used to ...
Shichao Feng +6 more
doaj +1 more source
Disseminating Metaproteomic Informatics Capabilities and Knowledge Using the Galaxy-P Framework
Proteomes, 2018 The impact of microbial communities, also known as the microbiome, on human health and the environment is receiving increased attention. Studying translated gene products (proteins) and comparing metaproteomic profiles may elucidate how microbiomes ...
Clemens Blank +18 more
doaj +1 more source
Considerations for constructing a protein sequence database for metaproteomics
Computational and Structural Biotechnology Journal, 2022 Mass spectrometry-based metaproteomics has emerged as a prominent technique for interrogating the functions of specific organisms in microbial communities, in addition to total community function.
J. Alfredo Blakeley-Ruiz, Manuel Kleiner
doaj +1 more source
Assessing the Dark Field of Metaproteome
Analytical Chemistry, 2022 The human gut microbiome is a complex system composed of hundreds of species, and metaproteomics can be used to explore their expressed functions. However, many lower abundance species are not detected by current metaproteomic techniques and represent the dark field of metaproteomics.
Haonan Duan +6 more
openaire +3 more sources
Microbial metaproteome data from decayed beech dead wood
Data in Brief, 2020 Wood-decomposition in terrestrial ecosystems is a very important process with huge ecologic consequences. This decomposition process is a combination of biological respiration, leaching and fragmentation, mainly triggered by organismic activities.
Lydia Kipping +5 more
doaj +1 more source
Journal of Nutrition and Metabolism, 2010 The plant-based compounds rho-iso-alpha acids (RIAA) from Humulus lupulus (hops) and proanthocyanidins (PAC) from Acacia nilotica have been shown to modulate insulin signaling in vitro. We investigated their effects on triglyceride (TG) deposition in 3T3-
Deanna M. Minich +6 more
doaj +1 more source
Frontiers in Microbiology, 2023 IntroductionCholesterol gallstone disease is a prevalent condition that has a significant economic impact. However, the role of the bile microbiome in its development and the host’s responses to it remain poorly understood.MethodsIn this study, we ...
Xue-Ting Yang +6 more
doaj +1 more source
Frontiers in Microbiology, 2021 Creatine pyruvate (CrPyr) is a new multifunctional nutrient that can provide both pyruvate and creatine. It has been shown to relieve the heat stress of beef cattle by improving antioxidant activity and rumen microbial protein synthesis, but the ...
Yanjiao Li +6 more
doaj +1 more source
Which metaproteome? The impact of protein extraction bias on metaproteomic analyses
Molecular and Cellular Probes, 2013 Culture-independent techniques such as LC-MS/MS-based metaproteomic analyses are being increasingly utilized for the study of microbial composition and function in complex environmental samples. Although several studies have documented the many challenges and sources of bias that must be considered in these types of analyses, none have systematically ...
Dagmar Hajkova, Leary +4 more
openaire +2 more sources
Gut Microbes, 2021 Intestinal microbiota plays a key role in shaping host homeostasis by regulating metabolism, immune responses and behavior. Its dysregulation has been associated with metabolic, immune and neuropsychiatric disorders and is accompanied by changes in ...
Nicolas Nalpas +10 more
doaj +1 more source