First human study in treatment of unresectable liver metastases from colorectal cancer with irinotecan-loaded beads (DEBIRI) [PDF]
The objective of this pilot clinical study was to assess the safety, technical feasibility, pharmacokinetic (PK) profile and tumour response of DC Bead™ with irinotecan (DEBIRI™) delivered by intra-arterial embolisation for the treatment of metastatic ...
Hammerstingl, Renate Maria +6 more
core +1 more source
A systematic review of evidence on malignant spinal metastases : natural history and technologies for identifying patients at high risk of vertebral fracture and spinal cord compression [PDF]
Background: Spinal metastases can lead to significant morbidity and reduction in quality of life due to spinal cord compression (SCC). Between 5% and 20% of patients with spinal metastases develop metastatic spinal cord compression during the course of ...
M Connock +11 more
core +1 more source
Anaplastic thyroid carcinoma (ATC) is a highly aggressive endocrine tumor that can be expected to have a poor clinical outcome. Cutaneous metastases from ATC are rare and in the context of disseminated metastases.
Yun-Hsuan Lin +3 more
doaj +1 more source
Can localised 19F magnetic resonance spectroscopy pharmacokinetics of 5FU in colorectal metastases predict clinical response? [PDF]
Background 5-Fluorouracil remains widely used in colorectal cancer treatment more than 40 years after its development. 19F magnetic resonance spectroscopy can be used in vivo to measure 5FU’s half-life and metabolism to cytotoxic fluoronucleotides ...
Griffiths, John R. +17 more
core +1 more source
Clinical Evidence: Metastases can Metastasize
We report the unusual case of a 52-year-old female with known stable metastatic ovarian cancer presenting with a new, rapidly growing gastric metastasis, leading to surgical resection. Histologic assessment of the specimen revealed evidence of submucosal and intramuscular metastatic disease originating from a metastatic lesion and not from the primary ...
Stanley, Gregory A. +4 more
openaire +3 more sources
Adrenal insufficiency caused by bilateral adrenal metastases - a rare treatable cause for recurrent nausea and vomiting in metastatic breast cancer [PDF]
Background: Nausea and vomiting are common symptoms in patients with malignant disease. Several, sometimes rare causes have to be considered to decide the right treatment.
Bausewein, Claudia +2 more
core +1 more source
Metasin: An Intra-Operative Real-Time Quantitative Reverse Transcription Polymerase-Chain Reaction (RTqPCR) Assay to Detect Metastatic Breast Cancer in Sentinel Lymph Nodes [PDF]
The copyright of this thesis rests with the author and no quotation from it or information derived from it may be published without the prior written consent of the authorThe most important prognostic factor in breast cancer is the presence or absence of
Al-Ramadhani, Salma
core +4 more sources
Pancreatic ductal adenocarcinoma (PDAC) is often diagnosed when liver metastases already emerged. This study elucidated the impact of hepatic stromal cells on growth behavior of premalignant and malignant pancreatic ductal epithelial cells (PDECs). Liver
Lennart Lenk +18 more
doaj +1 more source
Andhika Rachman,1,2 Zaenal Hakiki Fiantoro,3 Noorwati Sutandyo,4 Dimas Priantono,1 Pradana Zaky Romadhon,5 Reganedgary Jonlean6 1Division of Hematology and Medical Oncology, Department of Internal Medicine, Faculty of Medicine, Universitas Indonesia, Dr.
Rachman A +5 more
doaj
Skeletal muscle metastases on magnetic resonance imaging: analysis of 31 cases
Aim of the study : To investigate the magnetic resonance imaging (MRI) features of skeletal muscle metastases (SMM). Material and methods: The records of 31 patients with proven SMM were retrospectively reviewed.
Qi Li +8 more
doaj +1 more source

