Results 211 to 220 of about 1,591,450 (336)

Bioengineered Lymphatic Vessels in Synthetic Matrices to Study Breast Cancer Cell Functions

Advanced Healthcare Materials, EarlyView.
Lymphatic vessels are involved in cancer metastasis. To study the interplay between metastasizing cancer cells and lymphatic vessels under highly reproducible conditions, advanced in vitro models are required. In this work, 3D lymphatic networks are formed in biomimetic hydrogels and their interactions with invasive and non‐invasive cancer cell‐lines ...
Rodi Odabasi, Lisa A. Krattiger, Magdalini Kanari, Mira A. Jacobs, Lukas O. Moser, Mark W. Tibbitt, Cornelia Halin, Martin Ehrbar   +7 more
wiley   +1 more source

Personalizing therapies over the course of hormone receptor-positive/HER2-negative metastatic breast cancer. [PDF]

CA Cancer J Clin
Singareeka Raghavendra A, Damodaran S, Barcenas CH, Fuqua SA, Layman RM, Tripathy D.   +5 more
europepmc   +1 more source

A 3D Bioprinted Spheroid‐Laden dECM‐Enriched Osteosarcoma Model for Enhanced Drug Testing and Therapeutic Discovery

Advanced Healthcare Materials, EarlyView.
A 3D biomimetic OS model was developed by bioprinting an OS‐cell‐derived dECM‐enriched bioink with OS spheroids incorporated. The model showed upregulation of known OS prognostic markers and increased resistance to doxorubicin, compared to 2D cultures and scaffold‐free spheroids, making this a more clinically relevant platform for drug discovery ...
Margarida F. Domingues, Maria Catarina Carreira, Mafalda S. Santos, Daniela Pacheco, Frederico Castelo Ferreira, Paola Sanjuan‐Alberte, João Carlos Silva   +6 more
wiley   +1 more source

Neutrophils matter: new clinical insights on their role in the progression of metastatic breast cancer. [PDF]

Breast Cancer Res
Correia BF, Grosa D, Salvador R, Brites I, Martins T, Vitorino M, Sousa CX, Cristóvão-Ferreira S, Braga S, Jacinto A, Cabral MG.   +10 more
europepmc   +1 more source

Photosensitizing Lipid Nanoparticles for Ferroptosis‐Enhanced Photodynamic Cancer Therapy via GPX4 Silencing

Advanced Healthcare Materials, EarlyView.
Photosensitizing lipid nanoparticles (PLNPs) are engineered by incorporating cholesterol–PEG–pheophorbide a into MC3‐based LNPs and encapsulating GPX4‐targeting siRNA. Upon light activation, PLNPs generate reactive oxygen species (ROS) while silencing GPX4 to induce ferroptosis.
Ga‐Hyun Bae, Seungyong Shin, Joo Dong Park, Eun‐Young Koh, Seunghyo Ko, Jieun Han, Chun Gown Park, Dong‐Hyun Kim, Kun Na, Wooram Park   +9 more
wiley   +1 more source

Adaptability of lung and liver metastatic breast cancer cells to glucose. [PDF]

Cancer Cell Int
Layosa MA, Sheeley MP, Raghavan A, Andolino C, Wendt MK, Hursting SD, Teegarden D.   +6 more
europepmc   +1 more source

Smart Catheters for Diagnosis, Monitoring, and Therapy

Advanced Healthcare Materials, EarlyView.
This study presents a comprehensive review of smart catheters, an emerging class of medical devices that integrate embedded sensors, robotics, and communication systems, offering increased functionality and complexity to enable real‐time health monitoring, diagnostics, and treatment. Abstract This review explores smart catheters as an emerging class of
Azra Yaprak Tarman, Samiha Ahmed, Majed Othman Althumayri, Megan Guy, Darlenne Chavez Lugo, Frances S. Ligler, George T. Ligler, Rahmi Oklu, Hiroshi Kawahira, Michael J. McShane, Jun Kameoka, Jonathan Bova, Hatice Ceylan Koydemir   +12 more
wiley   +1 more source

Trends in Survival and Mortality of "Early" Metastatic Breast Cancer in Northern Italy Following the Introduction of Targeted Therapies. [PDF]

Cancers (Basel)
Marinelli F, Braghiroli MB, Bisceglia I, Ferrari G, Morabito F, Giovanardi F, Pinto C, Mangone L.   +7 more
europepmc   +1 more source

The genomic landscape of metastatic breast cancer highlights changes in mutation and signature frequencies

Nature Genetics, 2019
L. Angus, M. Smid, S. Wilting, J. van Riet, Arne van Hoeck, Luan Nguyen, S. Nik-Zainal, T. Steenbruggen, V. Tjan-Heijnen, M. Labots, J. V. van Riel, H. Bloemendal, N. Steeghs, M. Lolkema, E. Voest, H. V. D. van de Werken, A. Jager, E. Cuppen, S. Sleijfer, J. Martens   +19 more
semanticscholar   +1 more source

Characterization of Microplastics in Human Gastric Cancer and Control Tissues and Analysis of Associated Genetic Features

Advanced Healthcare Materials, EarlyView.
This study characterizes the presence of microplastics in human normal gastric, para‐tumor, and gastric tumor tissue and confirms the association between microplastic exposure and lymph node metastasis in gastric cancer. This study explores the transcriptomic changes induced by microplastic exposure, laying the foundation for further investigation into
Liqiao Chen, Jialin Li, Yan Wu, Han Bao, Xuesong Yang, Guoqing Lv, Ke Ji, Ji Zhang, Xiaojiang Wu, Kai Zhou, Jieli Xu, Jiatian Tang, Xiyuan Han, Anqiang Wang   +13 more
wiley   +1 more source