Results 41 to 50 of about 376,342 (317)

Metastatic Breast Cancer to the Urinary Bladder in the Caribbean

Case Reports in Oncology, 2021
One of the most common cancers amongst women is breast cancer. The most common metastatic sites are the lymph nodes, lungs, liver, and bone. Metastatic spread to the urinary bladder is rare, and this case, as far as we are aware, is the first reported in
Saara Mohammed, Atiba Akii Bua
doaj   +1 more source

Trastuzumab (Herceptin (R)): Monoclonal antibody in the treatment of HER2/neu-overexpressing breast cancer in the metastatic and (neo)adjuvant situation [PDF]

, 2006
Trastuzumab (Herceptin (R)) is a humanized monoclonal antibody that specifically targets HER2/neu (human epidermal growth factor receptor-2) breast cancer cells, which are overexpressed in about 25-30% of breast carcinomas.
Bauerfeind, Ingo, Rückert, Sandra, Lenhard, Miriam, Ditsch, Nina, Kümper, Carolin, Kahlert, Steffen, Friese, Klaus, Untch, Michael   +7 more
core   +1 more source

Tumor markers in breast cancer - European Group on Tumor Markers recommendations [PDF]

, 2005
Recommendations are presented for the routine clinical use of serum and tissue-based markers in the diagnosis and management of patients with breast cancer.
Einarsson, Roland, Barak, Vivian, Dalen, Arie van, Duffy, Michael J., Nap, Marius, Gion, Massimo, Molina, Rafael, Lamerz, Rolf, Sölétormos, György, Goike, Helena, Stieber, Petra   +10 more
core   +1 more source

Clinical usefulness of cancer markers in primary breast cancer [PDF]

, 2011
The aim of this study was to investigate the diagnostic power of CA 549, MSA and CA 15-3 in identifying breast cancer. The study included 232 patients of which 56 were healthy, 43 had benign breast cancer and 191 with other growths.
Verring, A., Ziolkowski, Piotr, Oremek, Gerhard, Clouth, Aline   +3 more
core   +1 more source

Human WDR5 promotes breast cancer growth and metastasis via KMT2-independent translation regulation

eLife, 2022
Metastatic breast cancer remains a major cause of cancer-related deaths in women, and there are few effective therapies against this advanced disease.
Wesley L Cai, Jocelyn Fang-Yi Chen, Huacui Chen, Emily Wingrove, Sarah J Kurley, Lok Hei Chan, Meiling Zhang, Anna Arnal-Estape, Minghui Zhao, Amer Balabaki, Wenxue Li, Xufen Yu, Ethan D Krop, Yali Dou, Yansheng Liu, Jian Jin, Thomas F Westbrook, Don X Nguyen, Qin Yan   +18 more
doaj   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

Exercise as part of survivorship care in metastatic breast cancer: protocol for the randomized EMBody trial

BMC Cancer
Background Exercise is associated with improved survival, physical functioning, treatment tolerability, and quality of life in early-stage breast cancer. These same endpoints matter in metastatic breast cancer (MBC).
Martha A. Cancilla, Donya Nemati, Danielle Halsey, Niraj Shah, Melissa Sherman, Nicholas Kelly, Pengyue Zhang, Nada Kassem, Navin Kaushal, Kelly Shanahan, Lesley Kailani Glenn, Jennifer A. Ligibel, Tarah J. Ballinger   +12 more
doaj   +1 more source

Reducing stigma, isolation, and misconceptions in advanced breast cancer: a global expert review and call-to-action for 2025–2035 (Goal 8)

Breast
Despite significant advances in the diagnosis and treatment of advanced breast cancer (ABC), people living with the disease continue to experience profound social isolation on a global scale. The multifaceted physical, financial, and emotional challenges
Ranjit Kaur, Rania A. Azmi, Sarah Kutika Nyagabona, Eva Schumacher-Wulf, Stacy Lewis, Daniel Egbase, Alexandra Lewis, Georgia Attfield, Fatima Cardoso   +8 more
doaj   +1 more source

Sequential Metastatic Breast Cancer Chemotherapy:Should the Median be the Message?

Frontiers in Public Health, 2013
Background: Counseling and anticipatory guidance of the expected course of treatment for women newly diagnosed with metastatic breast cancer (MBC) are difficult due to multiple factors influencing survival following metastatic breast cancer therapy.
Su Yon eJung, Margaret eRosenzweig
doaj   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source