Results 41 to 50 of about 3,580,419 (303)

Sialic Acid Metabolism: A Key Player in Breast Cancer Metastasis Revealed by Metabolomics

Frontiers in Oncology, 2018
Metastatic breast cancer is currently incurable. It has recently emerged that different metabolic pathways support metastatic breast cancer. To further uncover metabolic pathways enabling breast cancer metastasis, we investigated metabolic differences in
Shao Thing Teoh, Martin P. Ogrodzinski, Martin P. Ogrodzinski, Christina Ross, Kent W. Hunter, Sophia Y. Lunt, Sophia Y. Lunt   +6 more
doaj   +1 more source

Detection of Tumor Cell-Specific mRNA in the Peripheral Blood of Patients with Breast Cancer-Evaluation of Several Markers with Real-Time Reverse Transcription-PCR [PDF]

, 2013
It is widely known that cells from epithelial tumors, e. g., breast cancer, detach from their primary tissue and enter blood circulation. We show that the presence of circulating tumor cells (CTCs) in samples of patients with primary and metastatic ...
Simone Hofmann, Kölbl, Alexandra C., Jeschke, Udo, Klaus Friese, Andergassen, Ulrich, Neugebauer, Julia, Alexandra Kölbl, Udo Jeschke, Matthias Ilmer, Julia Neugebauer, Ilmer, Matthias, Ulrich Andergassen, Engelstädter, Verena, Schindlbeck, Christian, Hofmann, Simone, Hutter, Stefan, Stefan Hutter, Ra C. Kölbl, Friese, Klaus, Verena Engelstädter, Christian Schindlbeck   +20 more
core   +1 more source

Network meta-analysis of eribulin versus other chemotherapies used as second- or later-line treatment in locally advanced or metastatic breast cancer

BMC Cancer, 2021
Background Eribulin mesylate (ERI; Halaven®) is a microtubule inhibitor approved in the United States for metastatic breast cancer patients with at least two prior chemotherapy regimens for metastatic breast cancer, and in the European Union in locally ...
Qi Zhao, Rachel Hughes, Binod Neupane, Kristin Mickle, Yun Su, Isabelle Chabot, Marissa Betts, Ananth Kadambi   +7 more
doaj   +1 more source

Emerging Intrinsic Therapeutic Targets for Metastatic Breast Cancer

Biology, 2023
Breast cancer is now the most common cancer worldwide, and it is also the main cause of cancer-related death in women. Survival rates for female breast cancer have significantly improved due to early diagnosis and better treatment.
Jiawei Li, Eyleen L. K. Goh, Ji He, Yan Li, Zhimin Fan, Zhigang Yu, Peng Yuan, Dong-Xu Liu   +7 more
doaj   +1 more source

ER and HER2 expression are positively correlated in HER2 non-overexpressing breast cancer. [PDF]

, 2012
INTRODUCTION: Estrogen receptor-α (ER) and human epidermal growth factor receptor 2 (HER2) positivity are inversely correlated by standard criteria. However, we investigated the quantitative relation between ER and HER2 expression at both RNA and protein
Yarnold, J, Drury, Suzanne, Barrett-Lee, P, Hills, Margaret, Salter, J, Lawrence, D, Harnett, AM, Cuzick, J, Earl, H, Sestak, I, Ma, NCRIABCT, Georges Sumo, A'Hern, R, Sestak, Ivana, Barrett-Lee, Peter Jeffrey, Dowsett, M, A'Hern, Roger, Robinson, A, Perren, T, Johnson, L, Harris, Adrian, George, WD, Bliss, JM, Dodwell, D, null null, Peter Barrett-Lee, Price, D, Foster, L, Poole, C, Isabel Pinhel, Suzanne Drury, Fernando, I, Dowsett, Mitch, Cuzick, Jack, Judith M Bliss, Barrett-Lee, Peter, Sumo, G, Raina, V, Hills, M, Roger A'Hern, Ivana Sestak, Adrian Harris, Janine Salter, Jack Cuzick, Bliss, Judith M., Brunt, AM, Peto, J, Drury, S, Bliss, Judith M, Sumo, Georges, Margaret Hills, Mitch Dowsett, Pinhel, Isabel, Harris, A, NCRI Adjuvant Breast Cancer Trial Management Group, Bliss, M, Pinhel, I, Salter, Janine   +57 more
core   +2 more sources

Lapatinib in the Treatment of Hormone Receptor-Positive/ErbB2-Positive Breast Cancer [PDF]

, 2010
In women with estrogen receptor(ER)- and ErbB2(HER2)-positive breast cancer, a vicious cycle is established between ER mechanisms of action and the growth factor receptor network, leading to enhanced cell proliferation and endocrine resistance.
Bauerfeind, Ingo, Elling, Dirk, Heinemann, Volker   +2 more
core   +1 more source

Human adipocytes stimulate invasion of breast cancer MCF-7 cells by secreting IGFBP-2. [PDF]

PLoS ONE, 2015
A better understanding of the effects of human adipocytes on breast cancer cells may lead to the development of new treatment strategies. We explored the effects of adipocytes on the migration and invasion of breast cancer cells both in vitro and in vivo.
Chen Wang, Chao Gao, Kui Meng, Haishi Qiao, Yong Wang   +4 more
doaj   +1 more source

Metastatic Breast Cancer to the Urinary Bladder in the Caribbean

Case Reports in Oncology, 2021
One of the most common cancers amongst women is breast cancer. The most common metastatic sites are the lymph nodes, lungs, liver, and bone. Metastatic spread to the urinary bladder is rare, and this case, as far as we are aware, is the first reported in
Saara Mohammed, Atiba Akii Bua
doaj   +1 more source

Markers for the identification of late breast cancer recurrence [PDF]

, 2015
This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work ...
Cuzick, J, Sestak, I
core   +1 more source

HER2 testing in breast cancer: Opportunities and challenges [PDF]

, 2006
Human epidermal growth factor receptor 2 (HER2) is overexpressed in 15-25% of breast cancers, usually as a result of HER2 gene amplification. Positive HER2 status is considered to be an adverse prognostic factor. Recognition of the role of HER2 in breast
Lebeau, Annette, Annette Lebeau
core   +1 more source