Results 171 to 180 of about 6,340,743 (257)

WDR72 Drives Esophageal Squamous Cell Carcinoma Progression by Inhibiting Autophagy via the PI3K/Akt/mTOR Pathway

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Esophageal squamous cell carcinoma (ESCC) is an aggressive malignancy with a high rate of recurrence and metastasis, necessitating the identification of novel therapeutic targets. WD repeat‐containing protein 72 (WDR72) has been linked to various cancers, but its specific biological function and underlying mechanism in ESCC remain largely ...
Hao Wu, Zhong‐Xiang Jiang, Zheng Jiang
wiley   +1 more source

Racial Disparities in Survival Outcomes for Metastatic Renal Cell Carcinoma with Sarcomatoid Differentiation: A SEER-Based Retrospective Analysis (2010-2020). [PDF]

Cancers (Basel)
Meng L, Malone X, Peng H, Mei L, Jiang C, Liu X, Wang QE, Hong F, Sood A, Wang SJ, Wu Q, Wang S, Wang P.   +12 more
europepmc   +1 more source

Heterogeneity Analyzed by CT‐Based Habitat Analysis for Clinical Management of Cancers: A Narrative Review

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Tumors are highly heterogeneous, and whole‐lesion radiomics analysis is a popular method for extracting texture features that reflect this heterogeneity, which can be used to build models for cancer diagnosis, staging, therapy response evaluation, and prognosis prediction.
Yang Zhang, Zhi‐Yan Jin, Min‐Ying Lydia Su   +2 more
wiley   +1 more source

Determinants of pancreatic tropism in metastatic renal cell carcinoma. [PDF]

JCI Insight
Xu H, Kapur P, Christie A, Nielsen AW, Perny A, Brandenburg O, Small C, Miyata J, Zhong H, Roberts C, Elias R, Tcheuyap V, Duarte C, van Bokhoven A, Panian J, Li H, Collier KA, Zynger D, Meza L, Beuselinck B, Agarwal N, Mortazavi A, Pal S, McKay R, Lam ET, Rajaram S, Brugarolas J.   +26 more
europepmc   +1 more source

Composite Inflammatory Score for Predicting Progression‐Free Survival in Metastatic Clear Cell Renal Cell Carcinoma Treated With First‐Line Toripalimab Plus Axitinib

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Routine inflammatory and nutritional markers may help stratify progression risk in metastatic clear cell renal cell carcinoma during immunotherapy‐based treatment. This single‐center retrospective study included 237 patients who received first‐line toripalimab plus axitinib therapy.
Yun‐Feng Wu, Jing‐Suo Wang, Chuan‐Ao Zhang, Fan Zhang, Zhi‐Yu Zhang   +4 more
wiley   +1 more source

Current Trends in Therapeutic Outcomes Among Patients With Metastatic Renal Cell Carcinoma of the Spine: A Systematic Review and Meta-Analysis. [PDF]

Global Spine J
Ndika TC, Woo J, Lee BT, Johnson E, Oguguo E, Rivera N, Ray EJ, Bello A, Tiako JD, Mohamed L, Larry Lo SF, Sciubba DM, De la Garza Ramos R, O'Toole JE, Chongsathidkiet P, Dalton T, Crowell KA, Von Isenburg M, Mullikin T, Erickson M, Goodwin CR.   +20 more
europepmc   +1 more source

Visual Parathyroid Identification in Thyroidectomy: A Decision Curve Analysis of Gland Preservation

The Laryngoscope, EarlyView.
Intraoperative visual identification remains the standard approach to parathyroid preservation during thyroidectomy, yet its accuracy has rarely been quantified against an objective reference. Among 50 suspected parathyroid specimens verified by fine‐needle aspiration PTH washout, expert consensus visual identification achieved 84.0% sensitivity but ...
Paveena Pithuksurachai, Warut Pongsapich, Noppadon Triprateepsilp, Cheerasook Chongkolwatana, Narin Ratanaprasert, Sanyaluck Wattanachalermyos   +5 more
wiley   +1 more source

Data‐Independent Acquisition Mass Spectrometry in Tumor Classification and Cancer Biomarker Research

Mass Spectrometry Reviews, EarlyView.
Abstract Cancer treatment is far from optimal also because current classification systems do not reflect the complex molecular status of the tumor and its phenotype in sufficient detail. To construct molecular tumor classifiers, omics tools provide complex molecular data reflecting many aspects from genotype to phenotype.
Jan Simonik, Petr Lapcik, Pavla Bouchalova, Pavel Bouchal   +3 more
wiley   +1 more source

Real-world comparative outcomes of first-line immune combinations (ICI-ICI vs ICI-TKI) in metastatic renal cell carcinoma with sarcomatoid features. [PDF]

Oncoimmunology
Rebuzzi SE, Di Costanzo F, Filippi R, Rescigno P, Fornarini G, Signori A, Masini C, Iacovelli R, Fanelli M, Dalla Volta A, Di Napoli M, Roviello G, Guida A, Lolli C, Caserta C, Berardi R, Sorarù M, Lombardo L, Pierantoni F, Verzoni E, Mennitto A, Scagliarini S, Tucci M, Vitale MG, Messina C, Bonomi L, Tondulli L, Deppieri FM, La Russa F, Formisano L, Ortega C, Maiorano BA, Dri A, Zai S, Cocorocchio E, De Tursi M, Fantinel E, Conteduca V, Nasso C, Sansi C, Nolè F, Zago G, Bronte E, Bozza G, Bertolotti F, Montobbio N, Banna GL, Buti S, Bimbatti D.   +48 more
europepmc   +1 more source

Analysis of Carbohydrates and Glycoconjugates by Matrix‐Assisted Laser Desorption/Ionization Mass Spectrometry: An Update for 2023–2024

Mass Spectrometry Reviews, EarlyView.
ABSTRACT The use of MALDI mass spectrometry for the analysis of carbohydrates and glycoconjugates is a well‐established technique and this comprehensive review is the twelfth update of the original article published in 1999 and brings coverage of the literature to the end of 2024.
David J. Harvey
wiley   +1 more source