Results 11 to 20 of about 18,529 (279)

Metatranscriptomics for Understanding the Microbiome in Food and Nutrition Science [PDF]

Metabolites
Microbiome science has greatly expanded our understanding of the diverse composition and function of gut microorganisms over the past decades. With its rich microbial composition, the microbiome hosts numerous functionalities essential for metabolizing ...
Christina F. Butowski, Yash Dixit, Marlon M. Reis, Chunlong Mu   +3 more
doaj   +3 more sources

Comparison between metatranscriptomics and viral metagenomics, 16S, and host transcriptomics for comprehensive profiling of the respiratory microbiome and host response [PDF]

Frontiers in Microbiology
IntroductionOmics-based studies focusing on a single kingdom, such as bacterial 16S gene sequencing, viral metagenomics, and human mRNA sequencing, are commonly used to explore the microbiome and its association with host responses.
Gregory Destras, Gregory Destras, Marina Sabatier, Marina Sabatier, Antonin Bal, Antonin Bal, Bruno Simon, Bruno Simon, Quentin Semanas, Hadrien Regue, Theophile Boyer, Dominique Ploin, Yves Gillet, Bruno Lina, Bruno Lina, Hussein Anani, Laurence Josset, Laurence Josset   +17 more
doaj   +2 more sources

Metagenomics Versus Metatranscriptomics of the Murine Gut Microbiome for Assessing Microbial Metabolism During Inflammation

Frontiers in Microbiology, 2022
Shotgun metagenomics studies have improved our understanding of microbial population dynamics and have revealed significant contributions of microbes to gut homeostasis. They also allow in silico inference of the metagenome.
Juan Jovel, Juan Jovel, Aissata Nimaga, Tracy Jordan, Sandra O’Keefe, Jordan Patterson, Aducio Thiesen, Naomi Hotte, Michael Bording-Jorgensen, Sudip Subedi, Jessica Hamilton, Eric J. Carpenter, Béatrice Lauga, Shokrollah Elahi, Karen L. Madsen, Gane Ka-Shu Wong, Gane Ka-Shu Wong, Gane Ka-Shu Wong, Andrew L. Mason   +18 more
doaj   +2 more sources

A metatranscriptomics strategy for efficient characterization of the microbiome in human tissues with low microbial biomass

Gut Microbes
The high background of host RNA poses a major challenge to metatranscriptome analysis of human samples. Hence, metatranscriptomics has been mainly applied to microbe-rich samples, while its application in human tissues with low ratio of microbial to host
Joana Pereira-Marques, Rui M. Ferreira, Ceu Figueiredo   +2 more
doaj   +2 more sources

Spatial metatranscriptomics resolves host–bacteria–fungi interactomes

Nature Biotechnology, 2023
The interactions of microorganisms among themselves and with their multicellular host take place at the microscale, forming complex networks and spatial patterns.
Sami Saarenpää, Orly Shalev, Haim Ashkenazy, Vanessa Carlos, D. Lundberg, Detlef Weigel, Stefania Giacomello   +6 more
semanticscholar   +3 more sources

Microbiomes, Their Function, and Cancer: How Metatranscriptomics Can Close the Knowledge Gap [PDF]

International Journal of Molecular Sciences, 2023
The interaction between the microbial communities in the human body and the onset and progression of cancer has not been investigated until recently.
Lina Aitmanaitė, Karolis Širmonaitis, Giancarlo Russo   +2 more
openalex   +2 more sources

Enhancing infectious intestinal disease diagnosis through metagenomic and metatranscriptomic sequencing of 1000 human diarrhoeal samples [PDF]

Genome Medicine
Background Current surveillance of diarrhoeal disease is hindered by limitations of traditional diagnostic approaches, which often fail to identify the causative organism, particularly for novel or hard-to-culture bacterial pathogens.
Edward Cunningham-Oakes, Blanca M. Perez-Sepulveda, Yan Li, Jay C. D. Hinton, Charlotte A. Nelson, K. Marie McIntyre, Maya Wardeh, Sam Haldenby, Richard Gregory, Miren Iturriza-Gómara, Christiane Hertz-Fowler, Sarah J. O’Brien, Nigel A. Cunliffe, Alistair C. Darby, on behalf of the INTEGRATE consortium   +14 more
doaj   +2 more sources

Understanding human health through metatranscriptomics.

Trends in Molecular Medicine, 2023
Metatranscriptomics has revolutionized our ability to explore and understand transcriptional programs in microbial communities. Moreover, it has enabled us to gain deeper and more specific insight into the microbial activities in human gut, respiratory, oral, and vaginal communities. Perhaps the most important contribution of metatranscriptomics arises,
Teija Ojala, E. Kankuri, M. Kankainen
semanticscholar   +5 more sources

SAMSA: a comprehensive metatranscriptome analysis pipeline [PDF]

BMC Bioinformatics, 2016
BackgroundAlthough metatranscriptomics-the study of diverse microbial population activity based on RNA-seq data-is rapidly growing in popularity, there are limited options for biologists to analyze this type of data.
Danielle G. Lemay, David A. Mills, Ian Korf, Samuel T. Westreich   +3 more
core   +6 more sources

Evaluation of commercial RNA extraction kits for long-read metatranscriptomics in soil

Microbial Genomics
Metatranscriptomic analysis of the soil microbiome has the potential to reveal molecular mechanisms that drive soil processes regulated by the microbial community.
Dan Barber, Christian A. Davies, Iain P. Hartley, Richard Tennant   +3 more
openalex   +2 more sources