Results 11 to 20 of about 14,226 (247)
Sizing up metatranscriptomics [PDF]
The ISME Journal, 2012 Abstract A typical marine bacterial cell in coastal seawater contains only ∼200 molecules of mRNA, each of which lasts only a few minutes before being degraded. Such a surprisingly small and dynamic cellular mRNA reservoir has important implications for understanding the bacterium’s responses to environmental signals, as well as for ...
Mary Ann, Moran +12 more
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Combined analysis of microbial metagenomic and metatranscriptomic sequencing data to assess in situ physiological conditions in the premature infant gut. [PDF]
, 2020 Microbes alter their transcriptomic profiles in response to the environment. The physiological conditions experienced by a microbial community can thus be inferred using meta-transcriptomic sequencing by comparing transcription levels of specifically ...
Baker, Robyn +8 more
core +2 more sources
Unlocking the Hidden Genetic Diversity of Varicosaviruses, the Neglected Plant Rhabdoviruses
Pathogens, 2022 The genus Varicosavirus is one of six genera of plant-infecting rhabdoviruses. Varicosaviruses have non-enveloped, flexuous, rod-shaped virions and a negative-sense, single-stranded RNA genome. A distinguishing feature of varicosaviruses, which is shared
Nicolas Bejerman +2 more
doaj +1 more source
Use of Metatranscriptomics in Microbiome Research [PDF]
Bioinformatics and Biology Insights, 2016 The human intestinal microbiome is a microbial ecosystem that expresses as many as 100 times more genes than the human host, thereby constituting an important component of the human holobiome, which contributes to multiple health and disease processes.
Stavros Bashiardes +2 more
openaire +4 more sources
Gene finding in metatranscriptomic sequences [PDF]
BMC Bioinformatics, 2014 Metatranscriptomic sequencing is a highly sensitive bioassay of functional activity in a microbial community, providing complementary information to the metagenomic sequencing of the community. The acquisition of the metatranscriptomic sequences will enable us to refine the annotations of the metagenomes, and to study the gene activities and their ...
Wazim Ismail, Yuzhen Ye, Haixu Tang
openaire +2 more sources
Disease Models & Mechanisms, 2022 To elucidate the molecular mechanisms that manifest lung abnormalities during severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections, we performed whole-transcriptome sequencing of lung autopsies from 31 patients with severe COVID-19 and
Anshul Budhraja +18 more
doaj +1 more source
Metatranscriptomes from diverse microbial communities: assessment of data reduction techniques for rigorous annotation [PDF]
, 2014 Background Metatranscriptome sequence data can contain highly redundant sequences from diverse populations of microbes and so data reduction techniques are often applied before taxonomic and functional annotation.
Mock, Thomas +3 more
core +1 more source
Genomic and Transcriptomic Evidence Supports Methane Metabolism in
mSystems, 2020 Euryarchaeal lineages have been believed to have a methanogenic last common ancestor. However, members of euryarchaeal Archaeoglobi have long been considered nonmethanogenic and their evolutionary history remains elusive.
Yi-Fan Liu +9 more
doaj +1 more source
Gut Microbial Metabolism and Nonalcoholic Fatty Liver Disease. [PDF]
, 2019 The gut microbiome, the multispecies community of microbes that exists in the gastrointestinal tract, encodes several orders of magnitude more functional genes than the human genome. It also plays a pivotal role in human health, in part due to metabolism
Lynch, Susan V +3 more
core +1 more source
SAMSA2: a standalone metatranscriptome analysis pipeline [PDF]
BMC Bioinformatics, 2017 Abstract Background Complex microbial communities are an area of rapid growth in biology. Metatranscriptomics allows one to investigate the gene activity in an environmental sample via high-throughput sequencing.
Westreich, Samuel T +4 more
openaire +5 more sources