Results 21 to 30 of about 13,896 (217)

Combined analysis of microbial metagenomic and metatranscriptomic sequencing data to assess in situ physiological conditions in the premature infant gut. [PDF]

open access: yes, 2020
Microbes alter their transcriptomic profiles in response to the environment. The physiological conditions experienced by a microbial community can thus be inferred using meta-transcriptomic sequencing by comparing transcription levels of specifically ...
Baker, Robyn   +8 more
core   +2 more sources

Exploring the tymovirids landscape through metatranscriptomics data [PDF]

open access: yesArchives of Virology, 2021
AbstractTymovirales is an order of viruses with positive-sense, single-stranded RNA genomes that mostly infect plants, but also fungi and insects. The number of tymovirid sequences has been growing in the last few years with the extensive use of high-throughput sequencing platforms.
Nicolás Bejerman, Humberto Debat
openaire   +2 more sources

Unlocking the Hidden Genetic Diversity of Varicosaviruses, the Neglected Plant Rhabdoviruses

open access: yesPathogens, 2022
The genus Varicosavirus is one of six genera of plant-infecting rhabdoviruses. Varicosaviruses have non-enveloped, flexuous, rod-shaped virions and a negative-sense, single-stranded RNA genome. A distinguishing feature of varicosaviruses, which is shared
Nicolas Bejerman   +2 more
doaj   +1 more source

Metatranscriptomic assessment of burn wound infection clearance [PDF]

open access: yesClinical Microbiology and Infection, 2021
Peer ...
Ojala, Teija   +11 more
openaire   +3 more sources

Periodontal microbiology and microbial etiology of periodontal diseases: Historical concepts and contemporary perspectives

open access: yesPeriodontology 2000, EarlyView., 2023
Abstract This narrative review summarizes the collective knowledge on periodontal microbiology, through a historical timeline that highlights the European contribution in the global field. The etiological concepts on periodontal disease culminate to the ecological plaque hypothesis and its dysbiosis‐centered interpretation.
Georgios N. Belibasakis   +5 more
wiley   +1 more source

Gene finding in metatranscriptomic sequences [PDF]

open access: yesBMC Bioinformatics, 2014
Metatranscriptomic sequencing is a highly sensitive bioassay of functional activity in a microbial community, providing complementary information to the metagenomic sequencing of the community. The acquisition of the metatranscriptomic sequences will enable us to refine the annotations of the metagenomes, and to study the gene activities and their ...
Ismail, Wazim, Ye, Yuzhen, Tang, Haixu
openaire   +2 more sources

SAMSA2: a standalone metatranscriptome analysis pipeline [PDF]

open access: yesBMC Bioinformatics, 2017
AbstractBackgroundComplex microbial communities are an area of rapid growth in biology. Metatranscriptomics allows one to investigate the gene activity in an environmental sample via high-throughput sequencing. Metatranscriptomic experiments are computationally intensive because the experiments generate a large volume of sequence data and the sequences
Westreich, Samuel T   +4 more
openaire   +5 more sources

Metatranscriptomes from diverse microbial communities: assessment of data reduction techniques for rigorous annotation [PDF]

open access: yes, 2014
Background Metatranscriptome sequence data can contain highly redundant sequences from diverse populations of microbes and so data reduction techniques are often applied before taxonomic and functional annotation.
Mock, Thomas   +3 more
core   +1 more source

Molecular signature of postmortem lung tissue from COVID-19 patients suggests distinct trajectories driving mortality

open access: yesDisease Models & Mechanisms, 2022
To elucidate the molecular mechanisms that manifest lung abnormalities during severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections, we performed whole-transcriptome sequencing of lung autopsies from 31 patients with severe COVID-19 and
Anshul Budhraja   +18 more
doaj   +1 more source

Gut Microbial Metabolism and Nonalcoholic Fatty Liver Disease. [PDF]

open access: yes, 2019
The gut microbiome, the multispecies community of microbes that exists in the gastrointestinal tract, encodes several orders of magnitude more functional genes than the human genome. It also plays a pivotal role in human health, in part due to metabolism
Lynch, Susan V   +3 more
core   +1 more source

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