Results 71 to 80 of about 13,896 (217)

The occurrence of banana Fusarium wilt aggravates antibiotic resistance genes dissemination in soil

open access: yesEcotoxicology and Environmental Safety
The spread of antibiotic resistance genes (ARGs) and subsequent soil-borne disease outbreaks are major threats to soil health and sustainable crop production.
Jiabao Wang   +7 more
doaj   +1 more source

Functional Characteristics of the Flying Squirrel's Cecal Microbiota under a Leaf-Based Diet, Based on Multiple Meta-Omic Profiling

open access: yesFrontiers in Microbiology, 2018
Mammalian herbivores rely on microbial activities in an expanded gut chamber to convert plant biomass into absorbable nutrients. Distinct from ruminants, small herbivores typically have a simple stomach but an enlarged cecum to harbor symbiotic microbes;
Hsiao-Pei Lu   +14 more
doaj   +1 more source

Duodenal Metatranscriptomics to Define Human and Microbial Functional Alterations Associated with Severe Obesity: A Pilot Study

open access: yesMicroorganisms, 2020
Obesity is a multifactorial disorder, and the gut microbiome has been suggested to contribute to its onset. In order to better clarify the role of the microbiome in obesity, we evaluated the metatranscriptome in duodenal biopsies from a cohort of 23 ...
Ilaria Granata   +8 more
doaj   +1 more source

The effects of arbuscular mycorrhizal fungi (AMF) and Rhizophagus irregularis on soil microorganisms assessed by metatranscriptomics and metaproteomics

open access: yes, 2019
Arbuscular mycorrhizal fungi (AMF) form symbioses with approximately 80% of plant species and potentially benefit their hosts (e.g. nutrient acquisition) and the soil environment (e.g. soil aggregation).
Johnston, P.   +4 more
core   +1 more source

The rumen microbial metaproteome as revealed by SDS-PAGE [PDF]

open access: yes, 2017
This work was supported by the RuminOmics project and funded by the European Commission (Grant Agreement No. 289319). The Rowett Institute is funded by the Rural and Environment Science and Analytical Services Division (RESAS) of the Scottish Government.
Snelling, Timothy J., Wallace, R. John
core   +2 more sources

A Guide for Spatial Omics Technologies: Innovation, Evaluation, and Application

open access: yesAdvanced Science, EarlyView.
This review presents a strategy‐centric framework for spatial omics technologies, organizing methods by how spatial information is experimentally encoded. It compares key performance trade‐offs across sequencing‐ and imaging‐based approaches, examines computational and practical limitations, and highlights biomedical applications. The analysis provides
Xiaofeng Wu   +5 more
wiley   +1 more source

Integrating Human Intestinal Organoids into FDA'S New Approach Methodologies for Drug Discovery

open access: yesAdvanced Science, EarlyView.
Illustration summarizes how human intestinal organoids (HIOs) are becoming transformative in preclinical research. Preclinical drug discovery pipelines often rely on animal models for ADMET studies, even though interspecies ADME gaps, poor external validity, and high attrition rates are common.
Debarun Patra   +6 more
wiley   +1 more source

A metatranscriptomics strategy for efficient characterization of the microbiome in human tissues with low microbial biomass

open access: yesGut Microbes
The high background of host RNA poses a major challenge to metatranscriptome analysis of human samples. Hence, metatranscriptomics has been mainly applied to microbe-rich samples, while its application in human tissues with low ratio of microbial to host
Joana Pereira-Marques   +2 more
doaj   +1 more source

Metatranscriptomic Analysis of the Chicken Gut Resistome Response to In-Feed Antibiotics and Natural Feed Additives

open access: yesFrontiers in Microbiology, 2022
The emergence of resistance against common antibiotics in the gut microbiota is a major issue for both human and livestock health. This highlights the need for understanding the impact of such application on the reservoir of antibiotic resistance genes ...
Raju Koorakula   +9 more
doaj   +1 more source

Linking Genes to Microbial Biogeochemical Cycling Lessons from Arsenic [PDF]

open access: yes, 2017
The biotransformation of arsenic is highly relevant to the arsenic biogeochemical cycle. Identification of the molecular details of microbial pathways of arsenic biotransformation coupled with analyses of microbial communities by meta -omits can provide ...
Kappler, Andreas   +4 more
core   +1 more source

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