Results 141 to 150 of about 5,427 (217)

Technologies and Strategies for Metabolic and Molecular Imaging With Hyperpolarized MRI

open access: yesJournal of Magnetic Resonance Imaging, Volume 63, Issue 2, Page 310-327, February 2026.
ABSTRACT Conventional Magnetic Resonance Imaging (MRI) offers limited sensitivity for direct metabolic and molecular imaging using non‐proton nuclei due to low thermal nuclear spin polarization. Hyperpolarization (HP) technologies increase nuclear spin polarization by several orders of magnitude, overcoming this limitation to enable in vivo studies of ...
Alixander S. Khan, Christoffer Laustsen
wiley   +1 more source

The Effect of Low Socioeconomic Status on the Leptin‐to‐Adiponectin Ratio

open access: yesNursing Open, Volume 13, Issue 2, February 2026.
ABSTRACT Aim(s) To examine the relationship between low socioeconomic status, stress, and chronic disease risk, and to explore leptin and adiponectin as upstream biomarkers of inflammation to inform evidence‐based nursing practice and policy. Design Integrative literature review guided by evidence‐based practice and lifecourse theory.
Jamie Rausch   +2 more
wiley   +1 more source

Pharmacometric‐Based Evaluation of Salmeterol and Its Metabolite α‐Hydroxysalmeterol in Plasma and Urine: Practical Implications for Doping Control

open access: yesCPT: Pharmacometrics &Systems Pharmacology, Volume 15, Issue 2, February 2026.
ABSTRACT Salmeterol is a commonly used β2‐agonist included on the List of Prohibited Substances and Methods published by the World Anti‐Doping Agency (WADA). We developed a population pharmacokinetic (popPK) model to describe the PK of salmeterol including its major metabolite, α‐hydroxysalmeterol, in plasma and urine after inhalation.
Paul Thoueille   +9 more
wiley   +1 more source

Design of Experiments (DoE)‐Optimized Polymeric Oxytocin Nanoparticles for Enhanced Nose‐to‐Brain Delivery

open access: yesSmall, Volume 22, Issue 8, 6 February 2026.
Intranasal (IN) delivery of PEGylated PLGA nanoparticles (NPs) loaded with oxytocin (OT) (OT‐NP‐PEG) is investigated as a strategy to enhance OT transport to the brain for treating autism and other neuropsychiatric disorders. The optimized NP formulation demonstrates appropriate physicochemical characteristics, improved stability, and enhanced mucosal ...
Naveed Ahmad   +11 more
wiley   +1 more source

The importance of inhaler devices: the choice of inhaler device may lead to suboptimal adherence in COPD patients

open access: yesInternational Journal of COPD, 2015
Josep Darbà,1 Gabriela Ramírez,2 Antoni Sicras,3 Pablo Francoli,4 Saku Torvinen,5 Rainel Sánchez-de la Rosa4 1Department of Economics, Universitat de Barcelona, 2BCN Health Economics and Outcomes Research SL, 3Dirección de ...
Darbà J   +5 more
doaj  

Aspiration of superabsorbent polymer beads in a 2‐year‐old Boston terrier

open access: yesVeterinary Record Case Reports, Volume 14, Issue 1, February 2026.
Abstract This case report describes the first documented instance of a dog aspirating a superabsorbent polymer bead, commonly marketed as Orbeez, and its successful removal. Superabsorbent polymers are widely used in children's toys and decorative products, and they possess the ability to expand significantly in water.
Damian Koc   +4 more
wiley   +1 more source

Differential peritoneal resident macrophage depletion and omental milky spot disruption after high versus low clodronate‐loaded liposome dose treatment

open access: yesImmunology &Cell Biology, Volume 104, Issue 2, Page 139-149, February 2026.
In this study, we found that intraperitoneal injection of a high (standard) clodronate‐loaded liposome dose induced persistent peritoneal macrophage depletion, paralleled by marked inflammation and compromised omental integrity. Conversely, low liposome dose caused transient macrophage depletion, low inflammation and no omental alterations, ensuring ...
Margarita Ferriz   +5 more
wiley   +1 more source

Endurance Training in Olympic Winter Sports: A Narrative Review of the Current Literature and Future Research Priorities

open access: yesScandinavian Journal of Medicine &Science in Sports, Volume 36, Issue 2, February 2026.
ABSTRACT The Milano‐Cortina 2026 Winter Olympics present an opportunity to synthesize evolving paradigms in endurance training within the broader context of long‐term athlete development. As Olympic winter sports span from endurance‐limited events to disciplines in which aerobic fitness primarily serves as a feeder capacity, a single training model is ...
Billy Sperlich, Hans‐Christer Holmberg
wiley   +1 more source

Effects of cAMP and CFTR modulation on apical fluid pH in human airway Calu‐3 cells

open access: yesPhysiological Reports, Volume 14, Issue 3, February 2026.
Abstract The airway epithelium serves as the first line of defense against inhaled insults present in the external environment by acting as a physical barrier and through host defense mechanisms. Proper maintenance of these host defense mechanisms relies on the regulation of airway surface liquid (ASL) composition and properties, a process that is ...
Jenny P. Nguyen   +2 more
wiley   +1 more source

Welfare assessment of turkeys (Meleagris gallopavo gallopavo) on farm

open access: yesEFSA Journal, Volume 24, Issue 2, February 2026.
Abstract This Scientific Opinion assesses the welfare of turkeys of all ages (Meleagris gallopavo gallopavo) on farm in relation to the type and condition of the litter, type and availability of enrichment (including covered veranda and outdoor range), space allowance, concentrations of ammonia and carbon dioxide, effective environmental temperature ...
EFSA Panel Animal Health and Animal Welfare (AHAW)   +23 more
wiley   +1 more source

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