Results 51 to 60 of about 5,427 (217)

Metered dose inhalers free of chlorofluorocarbons [PDF]

BMJ, 1995
The metered dose inhaler, which is used by patients with asthma and chronic obstructive pulmonary disease, is about to undergo some substantial changes. Health professionals need to know why and how these changes are occurring so that they can ease their patients' transition from old to new. The reason for the changes lies in the thinning of the ozone
M, Partridge, A, Woodcock
openaire   +2 more sources

The comparative effectiveness of initiating fluticasone/salmeterol combination therapy via pMDI versus DPI in reducing exacerbations and treatment escalation in COPD: a UK database study [PDF]

, 2017
Rupert Jones,1 Jessica Martin,2 Vicky Thomas,3 Derek Skinner,4 Jonathan Marshall,5 Martina Stagno d’Alcontres,2 David Price2,6 1Clinical Trials and Health Research, Institute of Translational and Stratified Medicine, Plymouth University Peninsula ...
Jones, R, Marshall, J, Martin, J, Price, D, Skinner, D, Stagno d'Alcontres, M, Thomas, V   +6 more
core   +2 more sources

Potent and Long‐Lasting Immunogenicity Generated by LNP‐mRNA gE Antigen Against Varicella Zoster Virus via an AI‐Assisted Pipeline

Advanced Science, EarlyView.
This study designs a novel mRNA‐LNP vaccine targeting VZV glycoprotein E (gE) for herpes zoster via an AI‐assisted pipeline. Validated in mice and rhesus macaques, the mRNA‐LNP vaccine shows strong humoral and cellular immune responses, with CD4+ T‐cell responses more effective and durable than Shingrix, offering a promising prophylactic option ...
Kai Dong, Fang Liu, Dawei Wang, Yanfen Li, Man Zhang, Yuting Zhou, Gengshen Song   +6 more
wiley   +1 more source

What to consider before prescribing inhaled medications: a pragmatic approach for evaluating the current inhaler landscape

Therapeutic Advances in Respiratory Disease, 2019
Inhaled therapies are the cornerstone of treatment in asthma and chronic obstructive pulmonary disease, and there are a multitude of devices available.
Federico Lavorini, Christer Janson, Fulvio Braido, Georgios Stratelis, Anders Løkke   +4 more
doaj   +1 more source

Comparison of Salbutamol Delivered Via Jet Nebulizer With A Metered Dose Inhaler (MDI) Plus A Spacer for Asthma Exacerbation of Children: A Randomized Clinical Trial

Acta Medica Iranica, 2020
Asthma is the most common chronic illness in children and is a major reason for pediatric emergency department visits. Beta-2 agonists are considered the most effective drugs for immediate relief in the symptoms.
Seyyed Ahmad Tabatabaii, Mahdieh Vahedi, Ghamartaj Khanbabaee, Saeed Sadr, Nazanin Farahbakhsh   +4 more
doaj   +1 more source

Delivery of inhalation drugs to children for asthma and other respiratory diseases [PDF]

, 2014
postprin
Chan, HK, Kwok, PCL
core   +1 more source

PTG‐Dependent Glycogen Metabolic Dysfunction Drives Impaired Adipose Browning: A Novel Mechanism Linking PM2.5 to Metabolic Disorders

Advanced Science, EarlyView.
This study provides the first evidence that PM2.5 impairs iWAT browning via PTG‐mediated glycogen metabolism disruption, which is initiated by ADRB3 inhibition and subsequently triggers VEGFB upregulation. It thereby delineates the ADRB3‐PTG‐VEGFB axis as central to PM2.5‐induced metabolic dysfunction and identifies adipose glycogen metabolism as a ...
Limin Wang, Renjie Hu, Yanxi Chai, Ping He, Sanduo Li, Lisha Zhao, Wenbin Zhao, Lu Zhang, Li Qin, Ran Li, Xiaoli Hou, Qinghua Sun, Cuiqing Liu   +12 more
wiley   +1 more source

Evaluation and Mitigation of Carbon Footprint of Medical Inhalers

Chemical Engineering Transactions, 2023
Pressurized metered dose inhalers (pMDIs) contain propellants with high Global Warming Potential. This paper compares six pMDI products from the Polish market in terms of their contribution to environmental burden by analyzing the release and residuals ...
Tomasz R. Sosnowski, Daniel Wylezinski, Andrzej Emeryk   +2 more
doaj   +1 more source

Holding chambers (spacers) versus nebulisers for beta-agonist treatment of acute asthma [PDF]

, 2013
Background In acute asthma inhaled beta₂-agonists are often administered by nebuliser to relieve bronchospasm, but some have argued that metered-dose inhalers with a holding chamber (spacer) can be equally effective.
Ba, Batra, Beasley, Benton, Berenberg, Burrows, Campbell, Cates, Cates, Chong-Neto, Chou, Coker, Colacone, Deerojanawong, Dewar, Direkwatanachai, Duarte, Fayaz, Ferrés, Freelander, Fuglsang, Gleeson, Hodder, Idris, Jasper, Kaashmiri, Kerem, Leversha, Levitt, Lin, Lipworth, Madsen, Maguire, Maldano-Alanis, Mandelberg, Mandelberg, Morgan, Morley, Morrone, Newman, Newman, Osmond, Parkin, Pendergast, Ploin, Ploin, Powell, Raimondi, Rao, Robertson, Rodrigo, Rodrigo, Rodrigo, Rowe, Rubilar, Salzman, Schuh, Shaikh, Shim, Sirikul, Summer, Tarala, Turner, Turner, Valencia, Vangveeravong, Vazquez Cordero, Vilarinho, Vivek, Wildhaber, Williams   +70 more
core   +1 more source

A Glucose‐Responsive Intelligent Antibacterial and Oxygen‐Producing Hydrogel Promotes the Healing of Diabetic Wounds by Regulating Cellular Heterogeneity

Advanced Science, EarlyView.
We have developed a glucose‐triggered on‐demand drug delivery CF‐CPGaMPN hydrogel based on borate ester bonds. It inactivates microbes, releases oxygen, and enables on‐demand drug release in high‐glucose environments to promote healing of diabetic wounds. Single‐cell sequencing reveals that the CF‐CPGaMPN hydrogel significantly alleviates dysfunctional
Manxuan Liu, Zhongcheng Li, Qian Ren, Ziqian Lu, Yubing Zhang, Yili Guo, Ruomeng Li, Die Hu, Linglin Zhang   +8 more
wiley   +1 more source