Results 171 to 180 of about 302,269 (383)

Effect of metformin on the level of aqueous humor inflammatory cytokines in patients with cataract

Scientific Reports
This study investigated the content of inflammatory cytokines in the aqueous humor (AH) of cataract patients with type 2 diabetes (T2DM) and explored the effect of metformin on the level of cytokines.
Jiaxi Li, Jiarui Yang, Ziyuan Liu, Xuemin Li   +3 more
doaj   +1 more source

Effects of metformin on tyrosine kinase activity, glucose transport, and intracellular calcium in rat vascular smooth muscle [PDF]

, 1996
Ligia J. Domínguez
openalex   +1 more source

Therapeutic reasoning in case reports: Insights into current reporting and learning opportunities

British Journal of Clinical Pharmacology, EarlyView.
Aims While case reports can help to train diagnostic reasoning, will they improve therapeutic reasoning as well? Prescribing the right medication is difficult and prone to error, which can lead to patient harm. Therefore, good therapeutic reasoning skills are essential.
Mariëlle G. Hartjes, Roos C. H. Schilder, Robert J. van Unen, Milan C. Richir, Michiel A. van Agtmael, Jelle Tichelaar   +5 more
wiley   +1 more source

Liraglutide for the treatment of type 2 diabetes : a single technology appraisal [PDF]

, 2011
This paper presents a summary of the Evidence Review Group (ERG) report into the clinical effectiveness and cost-effectiveness of liraglutide in the treatment of type 2 diabetes mellitus, based upon the manufacturer’s submission to the National ...
Cummins, E. (Ewen), Royle, Pamela, Shyangdan, D. (Deepson), Waugh, Norman   +3 more
core  

Metformin inhibits melanin synthesis and melanosome transfer through the cAMP pathway

Scientific Reports
Several studies have demonstrated the inhibitory effect of metformin on pigmentation. However, the effect of metformin on melanosome transfer remains unknown.
Xing Liu, Xiaojie Sun, Yunyao Liu, Wenzhu Wang, Hedan Yang, Yiping Ge, Yin Yang, Xu Chen, Tong Lin   +8 more
doaj   +1 more source

High dietary salt enhances acute depressor responses to metformin [PDF]

, 1999
Martin S. Muntzel
openalex   +1 more source

Reduction in the incidence of type 2 diabetes with lifestyle intervention or metformin.

New England Journal of Medicine, 2002
W. Knowler, E. Barrett-Connor, S. Fowler, R. Hamman, J. Lachin, Elizabeth A. Walker, David M. Nathan   +6 more
semanticscholar   +1 more source

Setting up mother–infant pair lactation studies with biobanking for research according to regulatory requirements

British Journal of Clinical Pharmacology, EarlyView.
Within the ConcePTION project we set out to design two mother–infant pair studies collecting breast milk and plasma from the mother and plasma from the infant (for metformin and prednisolone) in order to demonstrate the premises and conditions for investigating potential drug transfer in association with breastfeeding.
Mats Hansson, Ida Björkgren, Jenny Svedenkrans, Helena Backman, Jarl Hellman, Linda Englund‐Ögge, Mikaela Magnusson, Inger Lindström, Andrea Wutte, Erica Sundell, Pawel Baranczewski, Laura Shaughnessy   +11 more
wiley   +1 more source

Folate administration reduces circulating homocysteine levels in NIDDM patients on long‐term metformin treatment [PDF]

, 1998
Aasne K. Aarsand, Carlsen
openalex   +1 more source

From Genome to Geroscience: How DNA Damage Shapes Systemic Decline

BioEssays, EarlyView.
Persistent DNA damage triggers systemic secretory responses including damage‐associated molecular patterns (DAMPs), the senescence‐associated secretory phenotype (SASP), and extracellular vesicles (EVs). This non‐cell‐autonomous signaling disrupts intercellular communication, driving organism‐wide dysfunction and aging, and offering new therapeutic ...
Athanasios Siametis, George A. Garinis
wiley   +1 more source