Results 171 to 180 of about 297,887 (387)

Metformin allergy

open access: yesIndian Journal of Pharmacology, 2011
Metformin is an important antidiabetic agent that is widely used for diabetic patients. Here, a case of metformin allergy, presenting with skin lesions, is reported.
openaire   +3 more sources

Treatment With Phosphodiesterase 5 Inhibitors and Long‐Term Outcomes in Patients Undergoing Coronary Angiography and Cardiac Catheterization

open access: yesCatheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Background The effects of phosphodiesterase 5 (PDE5) inhibitors on the incidence of long‐term outcomes in patients with cardiovascular disease are not well understood. Objective: We studied the association between PDE5 inhibitor therapy and the incidence of adverse cardiovascular major adverse cardiovascular events (MACE) in patients ...
Sumon Roy   +5 more
wiley   +1 more source

First‐in‐Human Phase 1 Study to Evaluate the Clinical Pharmacology Properties of RBN‐3143, a Novel Inhibitor of Mono‐Adenosine Diphosphate Ribosyltransferase‐PARP14

open access: yesClinical Pharmacology in Drug Development, EarlyView.
Abstract RBN‐3143 is an inhibitor of PARP14 in development for inflammatory diseases. Multiple assessments were conducted to evaluate the clinical pharmacology properties of RBN‐3134. A randomized, double‐blind, placebo‐controlled study assigned healthy volunteers (HVs) to single ascending doses (SADs) (25‐1000 mg) or multiple ascending doses (MADs ...
Thomas M. Polasek   +9 more
wiley   +1 more source

A Thermodynamic Scale of Multiple Bonds Reducibility Based on G4 Calculations

open access: yesChemPhysChem, EarlyView.
An original scale for the reducibility of multiple bonds is established through G4 theoretical calculations in two steps: 1) comparing the gas heats of formation (ΔfH°) derived from G4 theoretical calculations with experimental values from NIST and ATcT, and 2) using the calculated ΔfH° (G4) to determine the hydrogenation enthalpies (ΔH2H ...
José Elguero, Ibon Alkorta
wiley   +1 more source

Metformin inhibits melanin synthesis and melanosome transfer through the cAMP pathway

open access: yesScientific Reports
Several studies have demonstrated the inhibitory effect of metformin on pigmentation. However, the effect of metformin on melanosome transfer remains unknown.
Xing Liu   +8 more
doaj   +1 more source

A Review of the Anti-diabetic Activity of Andrographis Paniculata (Burm. F.) Nees Based In-vivo Study [PDF]

open access: yes, 2015
Diabetes mellitus (DM) is ricing nowadays. DM is a metabolic deasease characterized by increasing of glucose blood level for prolonged time. Patient with DM must take medicine for lowering glucose levels in whole life.
Harimurti, S. (Sabtanti)   +1 more
core  

A Joint Pharmacometric Model of Iohexol and Creatinine Administered through a Meat Meal to Assess GFR and Renal OCT2/MATE Activity

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Accurately assessing glomerular filtration rate (GFR) from plasma creatinine concentrations is challenging in patients with unstable renal function. This study aimed to refine the understanding of creatinine kinetics for more reliable assessments of GFR and net creatinine tubular secretion (nCTS) via OCT2/MATE in humans.
Zhendong Chen   +5 more
wiley   +1 more source

Home - About - Disclaimer - Privacy