Results 181 to 190 of about 297,887 (387)

The durability of oral diabetic medications: Time to A1c baseline and a review of common oral medications used by the primary care provider. [PDF]

open access: yes, 2018
Introduction:Cost of generic medications has risen more in the past few years than any other time in history. While medical insurance covers much of these costs, health care professionals can better provide medications that have the longest duration of ...
Cherukuri, Lavanya   +2 more
core  

Predicting OCT2/MATEs‐Mediated Drug Interactions in Healthy Volunteers and Patients with Chronic Kidney Disease: Insights from Extended Clearance Concept, Endogenous Biomarkers, and In Vitro Inhibition Studies (Perspectives from the International Transporter Consortium)

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Organic cation transporter (OCT) 2 and multidrug and toxin extrusion (MATE) transporters play significant roles in the renal secretion of organic cations and drug–drug interactions (DDIs). Recent in vitro studies indicate that the Ki values for OCT2 exhibit substrate dependency and increase in potency with pre‐incubation.
Satoshi Asano   +8 more
wiley   +1 more source

The Effect of Metformin on Pregnancy Outcome Among Filipino Women with Polycystic Ovary Syndrome

open access: yesJournal of the ASEAN Federation of Endocrine Societies, 2014
Objective.To determine the effect of metformin on maternal and neonatal outcome among pregnant Filipino women with polycystic ovary syndrome (PCOS).   Methodology.This is a retrospective cohort study of PCOS women who were on metformin treatment prior
May Uyking-Naranjo   +3 more
doaj  

Cellular energy stress induces AMPK-mediated regulation of YAP and the Hippo pathway. [PDF]

open access: yes, 2015
YAP (Yes-associated protein) is a transcription co-activator in the Hippo tumour suppressor pathway and controls cell growth, tissue homeostasis and organ size.
Guan, Kun-Liang   +7 more
core  

Impact of Iron on the Crystallization of Rare Earth Sulphate Hydrates

open access: yesChemSusChem, Accepted Article.
Rare earth elements (REEs) are important for permanent magnets used in for example wind turbines and motors. There is an imbalance in supply and demand of this commodity and the REE have been identified as critical raw materials by the European Union. This study focuses on recovery of REEs from sulfuric acid solutions using antisolvent crystallization ...
Nitin Pawar   +5 more
wiley   +1 more source

Vascular effects of metformin Possible mechanisms for its antihypertensive action in the spontaneously hypertensive rat [PDF]

open access: bronze, 1996
Ramesh C. Bhalla   +5 more
openalex   +1 more source

Risk of colorectal cancer and cancer‐related mortality in type 2 diabetes patients treated with metformin, SGLT‐2 inhibitors, or their combination

open access: yes
Cancer Communications, EarlyView.
Xianhua Mao   +11 more
wiley   +1 more source

Beyond the Diagnostic Checklist: A Large‐Scale Analysis of Under‐Recognized Weight Loss Behaviors in Individuals With Eating Disorders

open access: yesInternational Journal of Eating Disorders, EarlyView.
ABSTRACT Objective This study aimed to explore the diverse range of weight loss behaviors that extend beyond traditional diagnostic criteria, highlighting the variability in symptom presentation. Method We text mined free‐text responses from 1675 participants with anorexia nervosa, bulimia nervosa, or binge‐eating disorder in the Genetic Links to ...
Saakshi Kakar   +11 more
wiley   +1 more source

Systemic aging fuels heart failure: Molecular mechanisms and therapeutic avenues

open access: yesESC Heart Failure, Volume 12, Issue 2, Page 1059-1080, April 2025.
Abstract Systemic aging influences various physiological processes and contributes to structural and functional decline in cardiac tissue. These alterations include an increased incidence of left ventricular hypertrophy, a decline in left ventricular diastolic function, left atrial dilation, atrial fibrillation, myocardial fibrosis and cardiac ...
Zhuyubing Fang   +7 more
wiley   +1 more source

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