Metformin treatment reduces ovarian cytochrome P-450c17α response to human chorionic gonadotrophin in women with insulin resistance-related polycystic ovary syndrome [PDF]
Antonio La Marca+6 more
openalex +2 more sources
Opposing adrenergic actions of intravenous metformin on arterial pressure in female spontaneously hypertensive rats [PDF]
Jacob D. Peuler
openalex +1 more source
This review highlights the complex roles of cellular senescence in cancer progression and suppression, discusses the mechanisms and regulatory pathways involved, and evaluates the efficacy of the “One‐Two punch” sequential treatment approach while addressing emerging challenges in this novel therapeutic strategy.
Qiuming Pan+12 more
wiley +1 more source
R-211. Excessive withdrawal bleeding after the insulin sensitising drug ‘metformin’ in a patient with chronic hypo- or anovulatory cycles [PDF]
J.G. Dolfing+4 more
openalex +1 more source
Efficient drug delivery to the posterior segment of the eye has long been a challenging issue due to the complex ocular barriers. The review focuses on the promise held by nanoplatforms for barrier penetration and the key mechanisms involved, also highlighting their advantages in achieving efficient drug delivery and superior treatment of PSEDs ...
Yifan Shen+7 more
wiley +1 more source
Objectives To examine the associations between antidiabetic medication type and a new episode of depression using 100% Texas Medicare database during 2009 and 2018.Design A retrospective cohort study.Setting A population-based study using the Texas ...
Holly M Holmes+3 more
doaj +1 more source
Metformin Decreases Food Consumption and Induces Weight Loss in Subjects with Obesity with Type II Non‐Insulin‐Dependent Diabetes [PDF]
Amy S. Lee, John E. Morley
openalex +1 more source
The immunosuppressive tumor microenvironment, characterized by hypoxia, redox imbalance, elevated interstitial fluid pressure, and acidity, was comprehensively elucidated. This review discussed the etiology and consequences of the characteristics of the immunosuppressive tumor microenvironment, and analyzed the recent advancements in nanomaterials for ...
Wen Zhang+7 more
wiley +1 more source
The effect of metformin on biomarkers associated with breast cancer outcomes: a systematic review, meta-analysis, and dose–response of randomized clinical trials [PDF]
Chhabra, M.+9 more
core +2 more sources
Vascular effects of metformin Possible mechanisms for its antihypertensive action in the spontaneously hypertensive rat [PDF]
Ramesh C. Bhalla+5 more
openalex +1 more source