Results 61 to 70 of about 12,857 (207)

Evaluation of Soluble CD48 Levels in Patients with Allergic and Nonallergic Asthma in Relation to Markers of Type 2 and Non-Type 2 Immunity: An Observational Study

Journal of Immunology Research, 2018
CD48 is a costimulatory receptor associated with human asthma. We aimed to assess the significance of the soluble form of CD48 (sCD48) in allergic and nonallergic asthma.
Oded Breuer, Roopesh Singh Gangwar, Mansour Seaf, Ahlam Barhoum, Eitan Kerem, Francesca Levi-Schaffer   +5 more
doaj   +1 more source

Non-specific bronchial hyper-responsiveness in children with allergic rhinitis: relationship with the atopic status [PDF]

, 2003
An increased prevalence of bronchial hyper-responsiveness (BHR) has been demonstrated in children from a general population, and in non-asthmatic adults with allergic rhinitis.
Bonsignore, G., Bucchieri, S, Cibella, F, Cuttitta, G, Hopps, M, LA GRUTTA, Stefania, Passalacqua, G   +6 more
core   +1 more source

Polydatin Relieves Airway Remodeling by Inhibiting P2X7R–NLRP3‐Mediated Excessive Autophagy in Asthma

Immunity, Inflammation and Disease, Volume 14, Issue 4, April 2026.
ABSTRACT Background Asthma is characterized by chronic airway inflammation and remodeling. Polydatin (PD), a natural compound, has shown anti‐inflammatory potential, but its role in asthma‐related airway remodeling and the underlying mechanisms involving the P2X7R–NLRP3 inflammasome axis and autophagy remain unclear.
Guangxing Li, Liangchang Li, Zhiguang Wang, Yihua Piao, Yilan Song, Li Li, Chang Xu, Xiaowan Li, Guanghai Yan   +8 more
wiley   +1 more source

Occupational asthma follow-up — Which markers are elevated in exhaled breath condensate and plasma?

International Journal of Occupational Medicine and Environmental Health, 2014
Objectives: To search for optimal markers in the exhaled breath condensate (EBC), plasma and urine that would reflect the activity/ severity of occupational asthma (OA) after the withdrawal from the exposure to the allergen. Material and Methods: Markers
Daniela Pelclová, Zdenka Fenclová, Štěpánka Vlčková, Pavlína Klusáčková, Jindřiška Lebedová, Kamila Syslová, Jaromír Běláček, Marek Kuzma, Tomáš Navrátil, Sergey Zakharov, Petr Kačer   +10 more
doaj   +1 more source

Alterations in vasodilator-stimulated phosphoprotein (VASP) phosphorylation: associations with asthmatic phenotype, airway inflammation and β\u3csub\u3e2\u3c/sub\u3e-agonist use [PDF]

, 2006
Background Vasodilator-stimulated phosphoprotein (VASP) mediates focal adhesion, actin filament binding and polymerization in a variety of cells, thereby inhibiting cell movement.
Batra, Vikas, Cirelli, Rosemary, Foster, Gayle C., Hastie, Annette T., Hawkins, Gregory A., Peters, Stephen P., Rybinski, Katherine A., Wu, Min, Zangrilli, James G.   +8 more
core   +1 more source

Use of continuous positive airway pressure reduces airway reactivity in adults with asthma [PDF]

, 2012
Asthma is characterised by airway hyperreactivity, which is primarily treated with β-adrenergic bronchodilators and anti-inflammatory agents. However, mechanical strain during breathing is an important modulator of airway responsiveness and we have ...
Busk, Michael, Busk, Nancy, Gunst, Susan J., Hutchins, Janet, Puntenney, Paula, Tepper, Robert S., Yu, Zhangsheng   +6 more
core   +1 more source

Protective Role for Itaconate During Inhaled Allergen Challenge

Allergy, Volume 81, Issue 4, Page 1099-1110, April 2026.
Itaconate levels decrease in sputum following allergen inhalation in mild asthmatics, suggesting a dynamic metabolic response to airway challenge. Genetic deletion of Acod1 in mice did not alter airway inflammation or remodelling in response to chronic HDM exposure.
Gesa J. Albers, Patricia P. Ogger, Christina Michalaki, Helen Stölting, Simone A. Walker, Anna Caldwell, John M. Halket, Kathryn Duvall, Atia Batool, Lisha Joshi, Helen O'Brien, Cormac McCarthy, Timothy Hinks, Gail M. Gauvreau, Paul M. O'Byrne, Clare M. Lloyd, Adam J. Byrne   +16 more
wiley   +1 more source

Protective effects of different doses of inhaled fenoterol on methacholine-induced bronchoconstriction in asthmatic children [PDF]

, 1998
OBJECTIVE: To evaluate the protective effect of different doses of inhaled fenoterol (F) on bronchoconstriction induced by methacholine (M).DESIGN: randomized double-blind study.SETTING: Referrence center.PARTICIPANTS: 9 children (aged from 7 to 15 years
Bueno, Maria Poliana, Gomez, Irma Douglas, Naspitz, Charles Kirov, Silva, Marilia De Dirceu, Solé, Dirceu   +4 more
core   +1 more source

The Therapeutic Potential of Farm Dust Extracts in a Mouse Model of Eosinophilic Inflammation

Allergy, Volume 81, Issue 4, Page 1173-1192, April 2026.
Farm dust extract (FDE) treatment reduces airway eosinophilia, mucus overproduction, and MHC‐II expression on DCs, limiting antigen presentation and Th2 inflammation. It increases PD‐L1 on DCs, promoting T cell deactivation. Additionally, FDE enhances Tregs and upregulates CTLA‐4, reinforcing suppression.
Rabia Ülkü Korkmaz, Jimmy Omony, Xiaomei Tan, Markus Klotz, Guilherme Dragunas, Sirui Chen, Soni Shankhwar, Zeynep Ertüz, Christoph Müller, Mohab Ragab, Aicha Jeridi, Romina Augustin, Janna Nawroth, Theodore S. Kapellos, Bettina Rankl, Ali Önder Yildirim, Erika von Mutius   +16 more
wiley   +1 more source

Could Fractional Exhaled Nitric Oxide Test be Useful in Predicting Inhaled Corticosteroid Responsiveness in Chronic Cough? A Systematic Review [PDF]

, 2016
© 2016 Background Fractional exhaled nitric oxide (FENO) is a safe and convenient test for assessing T H 2 airway inflammation, which is potentially useful in the management of patients with chronic cough.
Chang, Yoon-Seok, Cho, Sang-Heon, Chung, Soo-Jie, Kang, Sung-Yoon, Kim, Byung-Keun, Kim, Ju-Young, Kim, Mi-Yeong, Lee, Byung-Jae, Lim, Kyung-Hwan, Moon, Sung-Do, Morice, Alyn H., Park, Heung-Woo, Sohn, Kyoung-Hee, Song, Woo-Jung, Won, Ha-Kyeong, Yang, Min-Suk   +15 more
core   +1 more source