Results 21 to 30 of about 726,838 (122)

Testes de broncoprovocação com metacolina e com exercício em bicicleta e corrida livre em crianças com asma intermitente Bronchial provocation tests using methacholine, cycle ergometer exercise and free running in children with intermittent asthma

Jornal de Pediatria, 2005
OBJETIVO: Comparar a responsividade de vias aéreas à metacolina e ao teste de exercício na bicicleta ergométrica e corrida livre em crianças com asma intermitente. MÉTODOS: Estudo randomizado.
Ana C. T. G. Souza, Carlos A. C. Pereira
doaj   +1 more source

HDAC8 inhibitor attenuates airway responses to antigen stimulus through synchronously suppressing galectin-3 expression and reducing macrophage-2 polarization

Respiratory Research, 2020
Background This study was to investigate of the mechanism by which histone deacetylase (HDAC) 8 inhibitor ameliorated airway hyperresponsiveness (AHR) and allergic airway inflammation.
Meng-lu Li, Xin-ming Su, Yuan Ren, Xuan Zhao, Ling-fei Kong, Jian Kang   +5 more
doaj   +1 more source

Experimental evaluation of the nonselective and selective TMEM16 family calcium-activated chloride channel blockers in the airways

European Pharmaceutical Journal, 2023
Background The family of calcium-activated chloride channels, TMEM16, plays a significant role in contributing to the pathogenesis of airway inflammatory diseases.
J. Mažerik, L. Smieško, L. Fedorova, E. Gondáš   +3 more
semanticscholar   +1 more source

Issues Determining Direct Airways Hyperresponsiveness in Mice

Frontiers in Physiology, 2012
Airways hyperresponsiveness (AHR) is frequently a primary outcome in mouse models of asthma. There are, however, a number of variables that may affect the outcome of such measurements and the interpretation of the results.
Lennart Karl, Alf Lundblad
doaj   +1 more source

The effect of L-arginine on guinea-pig and rabbit airway smooth muscle function in vitro

Brazilian Journal of Medical and Biological Research, 1998
We have investigated the effects of L-arginine, D-arginine and L-lysine on airway smooth muscle responsiveness to spasmogens in vitro. Both L-arginine and D-arginine (100 mM) significantly reduced the contractile potency and maximal contractile response ...
A.C. Perez, W. Paul, S. Harrison, C.P. Page, D. Spina   +4 more
doaj   +1 more source

Molecular and pharmacological characterization of an acetylcholine-gated chloride channel (ACC-2) from the parasitic nematode Haemonchus contortus

International Journal for Parasitology: Drugs and Drug Resistance, 2018
Nematode cys-loop ligand-gated ion channels (LGICs) have been shown to be attractive targets for the development of novel anti-parasitic drugs. The ACC-1 family of receptors are a unique group of acetylcholine-gated chloride channels present only in ...
Sarah A. Habibi, Micah Callanan, Sean G. Forrester   +2 more
doaj   +1 more source

Protector mechanisms of the association between gastroesophageal reflux disease and asthma: experimental study in rats Mecanismos protetores: doença do refluxo gastroesofágico e asma. Estudo experimental em ratos

Arquivos de Gastroenterologia, 2008
BACKGROUND: It is well known the association between gastroesophageal reflux disease and asthma. The hyperreactivity of the airways is a characteristic of an asthmatic.
Paula Yuri Sugishita Kanikadan, Jayme Antonio Aboin Sertié, Ricardo Martins Oliveira-Filho, Wothan Tavares de Lima   +3 more
doaj   +1 more source

Efeito do salbutamol liberado através de inalador de pó seco sobre o broncoespasmo induzido por metacolina Effects of salbutamol delivered by dry-powder inhaler on methacholine-induced bronchoconstriction

Jornal Brasileiro de Pneumologia, 2004
INTRODUÇÃO: Os beta2-agonistas de curta duração sob a forma de nebulímetro pressurizado são os fármacos utilizados rotineiramente na reversão do broncoespasmo induzido pela metacolina.
Adalberto Sperb Rubin, Liliana G Pelegrin, Christiano Perin, MaurÍcio Roux Leite, Luiz Carlos Corrêa da Silva   +4 more
doaj   +1 more source

Effect of Bronchial Thermoplasty on Airway Closure

Clinical Medicine Insights: Circulatory, Respiratory and Pulmonary Medicine, 2007
Background Bronchial Thermoplasty, a procedure that applies thermal energy to the airway wall has been shown to impair the ability of airway to contract in response to methacholine chloride (Mch).
Robert Brown, William Wizeman, Christopher Danek, Wayne Mitzner   +3 more
doaj   +1 more source

Body Biofluids for Minimally‐Invasive Diagnostics: Insights, Challenges, Emerging Technologies, and Clinical Potential

Advanced Healthcare Materials, Volume 15, Issue 4, 26 January 2026.
Recent advances in diagnostics have accelerated the development of miniaturized wearable technologies for the continuous monitoring of diseases. This paradigm is shifting healthcare away from invasive, centralized blood tests toward decentralized monitoring, using alternative body biofluids.
Lanka Tata Rao, Chandan Kumar Mandal, Fernando Patolsky   +2 more
wiley   +1 more source