Effects of helium-oxygen on respiratory mechanics, gas exchange, and ventilation-perfusion relationships in a porcine model of stable methacholine-induced bronchospasm [PDF]
Objective: To explore the consequences of helium/oxygen (He/O2) inhalation on respiratory mechanics, gas exchange, and ventilation-perfusion (VA/Q) relationships in an animal model of severe induced bronchospasm during mechanical ventilation.
Clerbaux, Thierry +8 more
core
The selective overexpression of constitutively activated STAT6vt in lung Club cells results in enhanced mucus production and expression of the resistin‐like molecule alpha. This alteration shows no impact on eosinophil recruitment, N. brasiliensis infection, A. fumigatus induced allergic airway inflammation, or influenza A virus infection.
Andreas Ruhl +5 more
wiley +1 more source
Combined exposure to cigarette smoke and nontypeable Haemophilus influenzae drives development of a COPD phenotype in mice [PDF]
Background Cigarette smoke (CS) is the major etiologic factor of chronic obstructive pulmonary disease (COPD). CS-exposed mice develop emphysema and mild pulmonary inflammation but no airway obstruction, which is also a prominent feature ...
Beck, James M +5 more
core +1 more source
The Lower Urinary Tract Science Group Abstracts—ICI‐RS 2024
Neurourology and Urodynamics, Volume 44, Issue 3, Page 691-697, March 2025.
Christopher H. Fry +10 more
wiley +1 more source
Airway responsiveness to methacholine: effects of deep inhalations and airway inflammation. [PDF]
We determined the dose-response curves to inhaled methacholine (MCh) in 16 asthmatic and 8 healthy subjects with prohibition of deep inhalations (DIs) and with 5 DIs taken after each MCh dose. Flow was measured on partial expiratory flow-volume curves at
Barisione, G +5 more
core
Effect of terbutaline on hyperpnoea-induced bronchoconstriction and urinary club cell protein 16 in athletes [PDF]
This article is made available through the Brunel Open Access Publishing Fund and is distributed by the Creative Commons CC-BY 3.0 license, under which all are free to reuse or distribute the article under the condition that this original publication ...
Anderson, SD +5 more
core +2 more sources
SAPALDIA: Methods and participation in the cross-sectional part of the Swiss Study on Air Pollution and Lung Diseases in Adults [PDF]
Summary: SAPALDIA-the Swiss Study on Air Pollution and Lung Diseases in Adults-focuses on the long term health effects of low to moderate levels of air pollutants as typically seen in different parts of Switzerland.
Ackermann-Liebrich, Ursula +27 more
core
Autonomous sweat extraction and analysis applied to cystic fibrosis and glucose monitoring using a fully integrated wearable platform [PDF]
Perspiration-based wearable biosensors facilitate continuous monitoring of individuals’ health states with real-time and molecular-level insight. The inherent inaccessibility of sweat in sedentary individuals in large volume (≥10 µL) for on-demand and in
Challa, Samyuktha +13 more
core +3 more sources
Association between asthma control and bronchial hyperresponsiveness and airways inflammation: a cross-sectional study in daily practice. [PDF]
Summary Background The primary end-point in the management of asthma is to obtain optimal control. The aim of this study was to assess the relationships between the markers of airway inflammation (sputum eosinophilia and exhaled nitric oxide), bronchial ...
Henket, Monique +3 more
core +1 more source
Anti-angiogenic nanotherapy inhibits airway remodeling and hyper-responsiveness of dust mite triggered asthma in the Brown Norway rat [PDF]
Although angiogenesis is a hallmark feature of asthmatic inflammatory responses, therapeutic anti-angiogenesis interventions have received little attention. Objective: Assess the effectiveness of anti-angiogenic Sn2 lipase-labile prodrugs delivered via α(
Allen, John S +16 more
core +2 more sources

