Results 91 to 100 of about 51,765 (292)
Addiction, EarlyView.Abstract Background and aims Australia recently down‐scheduled and authorised psychedelic‐assisted therapies, including psilocybin, for certain mental health conditions. Evidence is emerging for potential application in substance use disorder treatment. However, regulatory developments have outpaced implementation readiness.
Sarah J. Catchlove +3 more
wiley +1 more source
Methadone and its effect on QTc prolongation. [PDF]
, 2009 Dear Editor – Methadone is a synthetic opioid which has been successful used in treating heroin addiction and chronic pain syndrome in palliative care for more than 30 years.
Keenan, Eamon +2 more
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Image1_PKA inhibition is a central step in D,L-methadone-induced ER Ca2+ release and subsequent apoptosis in acute lymphoblastic leukemia.JPEG [PDF]
Acute lymphoblastic leukemia (ALL) is a hematologic cancer that mostly affects children. It accounts for over a quarter of ALL pediatric cancers, causing most of the cancer death among children.
Ki-Young Lee (185268) +2 more
core +1 more source
Neuropsychological performance of methadone-maintained opiate users [PDF]
, 2014 Methadone maintenance treatment (MMT) has been used to treat opiate dependence since the mid-1960s. Previous studies have investigated the effects of methadone on cognitive function however the findings have been inconsistent.
Jensen, Maree +4 more
core +1 more source
Addiction, EarlyView.Abstract Background and aims Measurement‐based care (MBC) is a structured approach using standardized, repeated assessments to monitor treatment progress and guide clinical decision‐making. MBC improves outcomes for substance use treatment but can be time consuming due in part to lengthy assessment tools. Single‐item, patient‐reported outcome measures (
Thomas J. Reese +13 more
wiley +1 more source
Addiction, EarlyView.Abstract Aim We evaluated whether community‐level naloxone distribution, medication for opioid use disorder treatment and retention and incident high‐risk opioid prescribing rates were associated with opioid overdose death rates. Design Observational cohort conducted using 2019 to 2023 community‐level data as an exploratory analysis of the HEALing ...
Alexander Y. Walley +19 more
wiley +1 more source
Novel approaches for the synthesis of R- and S-methadone metabolites, and evaluation of their inhibitory activity against NMDA receptor [PDF]
, 2022 reservedLa depressione è un disturbo mentale comune caratterizzato da una tristezza grave e persistente che interferisce con le attività quotidiane e diminuisce il normale interesse e il piacere nelle attività.
TODESCHINI, ILEANA
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Addiction, EarlyView.Abstract Background and aims There has been an extensive literature describing the elevated risk of drug‐related death following an individual's release from prison; however, few previous studies have reported nationally representative samples or provided granular detail as to which individual drugs were deemed implicated in death.
Emmert Roberts +2 more
wiley +1 more source
More than 2,000 inmates receiving methadone treatment. [PDF]
, 2019 Figures contained in a new tender document issued by the Irish Prison Service (IPS) shows that 2,080 prisoners received drug treatment (methadone) last year, including 436 in Mountjoy and 210 in the adjoining Dochas women’s prison.
Baker, Noel
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Addiction, EarlyView.Abstract Background and aims Despite the well‐documented benefits of opioid substitution treatment (OST) in treating opioid dependence (OD), many people diagnosed with OD desire to live a drug‐free life. The transition to abstinence involves detoxification: a gradual dose reduction of OST to zero milligrams.
Amy Bagshaw +5 more
wiley +1 more source