Results 91 to 100 of about 51,637 (307)

Unlocking ‘stuckness’ and catalysing change: A qualitative study of clinician and service leader perspectives on psychedelic‐assisted therapy for substance use and mental health problems

open access: yesAddiction, EarlyView.
Abstract Background and aims Australia recently down‐scheduled and authorised psychedelic‐assisted therapies, including psilocybin, for certain mental health conditions. Evidence is emerging for potential application in substance use disorder treatment. However, regulatory developments have outpaced implementation readiness.
Sarah J. Catchlove   +3 more
wiley   +1 more source

Image3_PKA inhibition is a central step in D,L-methadone-induced ER Ca2+ release and subsequent apoptosis in acute lymphoblastic leukemia.JPEG

open access: yes
Acute lymphoblastic leukemia (ALL) is a hematologic cancer that mostly affects children. It accounts for over a quarter of ALL pediatric cancers, causing most of the cancer death among children.
Ki-Young Lee (185268)   +2 more
core   +1 more source

Patient‐reported outcomes for monitoring substance use treatment: A systematic review of single‐item measures

open access: yesAddiction, EarlyView.
Abstract Background and aims Measurement‐based care (MBC) is a structured approach using standardized, repeated assessments to monitor treatment progress and guide clinical decision‐making. MBC improves outcomes for substance use treatment but can be time consuming due in part to lengthy assessment tools. Single‐item, patient‐reported outcome measures (
Thomas J. Reese   +13 more
wiley   +1 more source

Pharmacological Characterization of the Mechanisms Involved in Delayed Calcium Deregulation in SH-SY5Y Cells Challenged with Methadone

open access: yesInternational Journal of Cell Biology, 2012
Previously, we have shown that SH-SY5Y cells exposed to high concentrations of methadone died due to a necrotic-like cell death mechanism related to delayed calcium deregulation (DCD).
Sergio Perez-Alvarez   +7 more
doaj   +1 more source

Death Attributed to Methadone

open access: yesPharmacopsychiatry, 2001
Besides its other effects, MMT (methadone maintenance treatment) reduces the high mortality of intravenous heroin addicts to about 30% of controls. On the other hand, deaths of patients and non-patients have been attributed to methadone. Here, we will report on the major reasons for deaths attributed to methadone and discuss suggestions for their ...
Vormfelde, Stefan Viktor   +1 more
openaire   +3 more sources

Ireland has 9,615 methadone users but care plans needed to get them drug-free.

open access: yes, 2014
In the last three years the number of people on methadone has increased, according to figures released by the Minister for Health James Reilly. Answering a parliamentary question on how many people the HSE provides opioid substitution, mainly ...

core  

Image5_PKA inhibition is a central step in D,L-methadone-induced ER Ca2+ release and subsequent apoptosis in acute lymphoblastic leukemia.JPEG

open access: yes
Acute lymphoblastic leukemia (ALL) is a hematologic cancer that mostly affects children. It accounts for over a quarter of ALL pediatric cancers, causing most of the cancer death among children.
Ki-Young Lee (185268)   +2 more
core   +1 more source

The association between naloxone distribution, buprenorphine treatment and retention and incident high‐risk opioid prescribing with opioid overdose death in Kentucky, Massachusetts, New York and Ohio, United States: An exploratory community‐level cohort study of data from the HEALing Communities Study

open access: yesAddiction, EarlyView.
Abstract Aim We evaluated whether community‐level naloxone distribution, medication for opioid use disorder treatment and retention and incident high‐risk opioid prescribing rates were associated with opioid overdose death rates. Design Observational cohort conducted using 2019 to 2023 community‐level data as an exploratory analysis of the HEALing ...
Alexander Y. Walley   +19 more
wiley   +1 more source

How more people died on methadone than heroin in Ireland.

open access: yes, 2014
More methadone users than heroin users died in one year in Ireland, according to new figures. The Health Research Board found that 113 methadone users died of an overdose in 2011, almost double the number of heroin users.

core  

Characteristics of deaths due to drug‐related causes among individuals recently released from prison in the United Kingdom, 1997–2025

open access: yesAddiction, EarlyView.
Abstract Background and aims There has been an extensive literature describing the elevated risk of drug‐related death following an individual's release from prison; however, few previous studies have reported nationally representative samples or provided granular detail as to which individual drugs were deemed implicated in death.
Emmert Roberts   +2 more
wiley   +1 more source

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