Results 81 to 90 of about 51,765 (292)
40% rise in methadone clients over the decade. [PDF]
, 2014 In excess of 9,500 clients received methadone maintenance treatment in 2013 — an increase of almost 40 per cent from levels in 2003 when the programme commenced, IMT reports.
Mudiwa, Lloyd
core
Image4_PKA inhibition is a central step in D,L-methadone-induced ER Ca2+ release and subsequent apoptosis in acute lymphoblastic leukemia.JPEG [PDF]
Acute lymphoblastic leukemia (ALL) is a hematologic cancer that mostly affects children. It accounts for over a quarter of ALL pediatric cancers, causing most of the cancer death among children.
Ki-Young Lee (185268) +2 more
core +1 more source
Methadone induced hypoglycemia, improved on dose adjustment
Journal of Clinical and Translational Endocrinology Case Reports, 2020 There exists reports in the literature that connects opioids with hypoglycemia, primarily methadone. We present a case of new onset hypoglycemia in a patient with end stage renal disease who was chronically on methadone.
Y. Otalora, S. Inkollu, S. Ursu
doaj +1 more source
Addiction, Volume 120, Issue 4, Page 745-755, April 2025.Abstract Aims The aim of this study was to identify longitudinal trajectories of medication for opioid use disorder (MOUD) use throughout 1 year following MOUD initiation and to examine the association of trajectory membership with HIV testing among people who inject drugs in India.
Allison M. McFall +8 more
wiley +1 more source
Exploring the role of mu opioid receptor (OPRM1) and CYP2B6 gene variations for methadone pharmacogenomics. Can these variations be used to advance toxicological interpretation post-mortem?. [PDF]
Methadone is increasingly involved in drug overdose cases and the molecular actions of the drug in vivo are largely unknown requiring elucidation. This study set out to examine the relationship between methadone toxicity and CYP2B6 and mu (μ) opioid ...
Bunten, Hannah
core
Heart ViewsMethadone is considered relatively safe when compared to other opioids. Methadone, however, can cause respiratory depression and QT prolongation. Among patients on methadone maintenance therapy, the rate of cannabis use is high.
Muhammad Adnan Zaman +2 more
doaj +1 more source
Western Journal of Medicine, 2000 Opiate dependence is a major public health problem associated with the transmission of deadly diseases (human immunodeficiency virus [HIV], hepatitis), criminal activity, accidental overdose, hospital admissions, and death. The treatment of opiate dependence is controversial, and in most patients, a lifelong duration is probably required.1 Methadone is
I B, Anderson, T E, Kearney
openaire +3 more sources
Psychedelic‐assisted treatment for substance use disorder: A narrative systematic review
Addiction, EarlyView.Abstract Background and aims This is the first systematic review of the extant literature on all major psychedelic‐assisted treatment for alcohol use disorder (AUD), tobacco use disorder (TUD) and other substance use disorders (SUD). We aimed to summarise the evidence for efficacy of psychedelic‐assisted treatment for AUD, TUD, and SUD; to evaluate its
Theodore Piper +7 more
wiley +1 more source
Image2_PKA inhibition is a central step in D,L-methadone-induced ER Ca2+ release and subsequent apoptosis in acute lymphoblastic leukemia.JPEG [PDF]
Acute lymphoblastic leukemia (ALL) is a hematologic cancer that mostly affects children. It accounts for over a quarter of ALL pediatric cancers, causing most of the cancer death among children.
Ki-Young Lee (185268) +2 more
core +1 more source
Resting EEG and ERPs findings in methadone-substituted opiate users: a review [PDF]
, 2015 Methadone has been used to treat opiate dependence since the mid-1960s. Despite its clinical effectiveness there is evidence from neuropsychological studies demonstrating that its long-term use might have negative effects on cognition.
Russell, Bruce R. +2 more
core +1 more source