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Integrating Methadone Into Primary Care: Lessons From Ukraine. [PDF]
Ann Intern MedLowenstein M, Thakrar A.
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Implementation challenges and opportunities in decentralized methadone service delivery. [PDF]
BMC Health Serv ResNkya IH +4 more
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Driving Distance From US Jails to Opioid Treatment Programs.
JAMA Netw OpenSaloner B +5 more
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American Journal of Hospice and Palliative Medicine®, 2008
Methadone hydrochloride is an old drug that has been in vogue off and on. It has complex pharmacodynamics and can be potentially fatal in inexperienced settings. Drug switching from an opioid to methadone or vice versa requires knowledge of equianalgesic dosing.
Chhabra, Shalini, Bull, Janet
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Methadone hydrochloride is an old drug that has been in vogue off and on. It has complex pharmacodynamics and can be potentially fatal in inexperienced settings. Drug switching from an opioid to methadone or vice versa requires knowledge of equianalgesic dosing.
Chhabra, Shalini, Bull, Janet
openaire +4 more sources
Methadone—Disulfiram Interaction During Methadone Maintenance
The Journal of Clinical Pharmacology, 1980In an attempt to characterize a possible drug interaction between methadone and disulfiram, 500 mg/day insulfiram was administered orally for seven days to seven subjects on methadone maintenance. Plasma methadone concentrations and urinary excretion of methadone and its pyrrolidine and pyrrolidone metabolites were measured and subjective symptoms of ...
T G, Tong, N L, Benowitz, M J, Kreek
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Disposition of methadone in methadone maintenance
Clinical Pharmacology & Therapeutics, 1975Six detoxified opiate addicts housed in a closed metabolic ward received methadone in stepwise increasing doses of 10, 20, 40, and 80 mg/day during 1 month. Four were given 14C‐methadone at the lowest dose and again at the highest dose. Of the subjects receiving radiomethadone, 2 excreted the major part of the radioactivity in urine and 2 about equally
E, Anggård +5 more
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Methadone and methadone metabolites in postmortem specimens
Forensic Science, Medicine, and Pathology, 2008We have determined drug/metabolite concentrations and ratios of methadone (METH) to two of its metabolites (EDDP, 2-ethylidene-1, 5-dimethyl-3, 3-diphenylpyrrolidine; and EMDP, 2-ethyl-5-methyl-3,3-diphenylpyrroline) in postmortem peripheral blood and liver tissue by liquid chromatography/tandem mass spectrometry.
Terry J, Danielson +2 more
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