Results 181 to 190 of about 94,112 (278)

Exercise during 14 days of head down tilt bedrest attenuates motor unit impairments in older humans

open access: yesExperimental Physiology, EarlyView.
Abstract Head‐down tilt bedrest (HDBR) models the effects of mechanical unloading on neuromuscular function. The efficacy of exercise in preserving motor unit (MU) function in older adults during HDBR remains unclear. This study investigated the effects of 14‐day HDBR on MU properties in older adults and the protective role of exercise.
Philippe St‐Martin   +8 more
wiley   +1 more source

Innovative Nanomaterial‐Based Approaches for the Recognition of Amphetamine in Attention Deficit Hyperactivity Disorder Management

open access: yesAnalytical Science Advances, Volume 7, Issue 1, June 2026.
ABSTRACT The rising incidence of amphetamine misuse, particularly in the context of attention deficit hyperactivity disorder treatment, underscores the urgent need for sensitive and effective detection methods. This review examines innovative nanomaterial‐based approaches for AMP detection, emphasizing their advantages over conventional analytical ...
Ilghar Zeinaly   +5 more
wiley   +1 more source

Major Adverse Cardiac Events with Ondansetron: A Systematic Review

open access: yesClinical Pharmacology &Therapeutics, Volume 119, Issue 4, Page 905-915, April 2026.
Evidence base: 170 randomized trials, 23,421 adults, predominantly single‐dose IV ondansetron, mean follow‐up 20 days. Observed outcomes: Major adverse cardiac events were rare, no ventricular arrhythmias or torsades de pointes observed. Conclusion: Ondansetron was not associated with increased mortality or serious cardiac arrhythmias in adult ...
Michael Cristian Garcia   +11 more
wiley   +1 more source

Astrocytes as central integrators of neural circuit function: Mechanisms and dysregulation in neuropsychiatric disorders

open access: yesClinical and Translational Discovery, Volume 6, Issue 2, April 2026.
1. Astrocytes are central integrators of neural circuit function through tripartite synapse modulation and neurovascular coupling. 2. Dysregulation of glutamate/GABA homeostasis and neuroinflammation represents shared mechanisms across diverse neuropsychiatric disorders. 3.
Xinyu Liu   +10 more
wiley   +1 more source

Methamphetamine

open access: yes
Methamphetamine (METH) is a highly addictive stimulant that affects the central nervous system. It is a widely abused psychostimulant. Monoaminergic neurotransmitter terminals are affected by METH intake. METH structure is very similar to amphetamine, a drug used to treat attention-deficit hyperactivity disorder (ADHD).
Patel P, Saadabadi A.
europepmc   +2 more sources

Forest Disturbance Drives Changes in the Functional Traits of Soil Bacteria: A Metagenomic Study of Kauri (Agathis australis) Forest Ecosystems

open access: yesEcology and Evolution, Volume 16, Issue 4, April 2026.
This study reveals how ecological disturbances reshape the structure and function of soil bacterial communities in kauri forests, which are critical for ecosystem resilience. By linking disturbance regimes to shifts in bacterial diversity and functional capacity, it highlights the wider effects of ecosystem disturbance on soil ecological function ...
Alexa K. Byers   +3 more
wiley   +1 more source

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