Results 191 to 200 of about 179,944 (271)

High‐Altitude Adaptation of Frogs (Case Study: Nanorana parkeri): From Physiological Phenotypes to AltitudeOmics

open access: yesIntegrative Zoology, EarlyView.
High altitudes are challenging for the animals that inhabit these environments. The Xizang plateau frog (Nanorana parkeri) survives in high‐altitude environments through a synergistic strategy of metabolic remodeling and protein expression adjustment to optimize energy efficiency and enhance cellular protection.
Xuejing Zhang   +6 more
wiley   +1 more source

INSL3 Expression in Leydig Cells is a Biomarker for Immunocastration in Boars: Transcriptional Evidence

open access: yesAndrology, EarlyView.
ABSTRACT Background Study aimed to obtain insights into physiological responses to immunocastration in pubertal boars by evaluating effects of alternative vaccination protocols and identifying a reliable immunocastration biomarker. Objectives It was hypothesized that the timing of gonadotropin‐releasing hormone (GnRH) suppression by immunocastration ...
Nina Batorek Lukač   +6 more
wiley   +1 more source

Mitochondrial Ca2+ overload is a pivotal risk factor for lethal ventricular arrhythmias due to the oxidation of mitochondrial respirasome and energetic failure

open access: yesBritish Journal of Pharmacology, EarlyView.
The data that support the findings of this study are available from the corresponding author upon reasonable request. Some data may not be made available because of privacy or ethical restrictions. Background and Purpose Ventricular arrhythmias are a leading cause of death among patients with cardiovascular diseases and are associated with elevated ...
Felipe de Jesús Salazar‐Ramírez   +13 more
wiley   +1 more source

Yeast Midas' touch: recent advances in the valorisation of methanol by yeasts. [PDF]

open access: yesWorld J Microbiol Biotechnol
Mauri A, García Tejada L, Blank LM.
europepmc   +1 more source

Songorine inhibits mitophagy in chronic heart failure via the TBC1D15/Fis1/Rab7A pathway

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Background and purpose Songorine (SGR) is an alkaloid extracted from Aconitum carichaelii Debx. and has a demonstrated role in cardiac dysfunction. Chronic heart failure (CHF) is a severe clinical syndrome leading to functional impairment and death, primarily due to the deterioration of energy metabolism in cardiomyocytes. However, the precise
Wenxiu Liu   +4 more
wiley   +1 more source

Targeting the noradrenergic‐metabolic axis: A new strategy for sugar‐induced depression subtypes

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Lifestyle is closely related to major depressive disorder (MDD). Given the growing focus on the impact of diet on mental health, this study examined how dietary habits affect the pathophysiology of MDD. Experimental Approach Health check‐up data were analysed. Mice received sucrose under chronic unpredictable mild stress
Takatoshi Sakata   +13 more
wiley   +1 more source

Methanogenic activities signatures in broilers fed black soldier fly (<i>Hermetia illucens</i>) larvae-based diets. [PDF]

open access: yesBiochem Biophys Rep
Ibiwoye DO   +6 more
europepmc   +1 more source

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