Pyrroloquinoline quinone: a potential neuroprotective compound for neurodegenerative diseases targeting metabolism [PDF]
Neural Regeneration ResearchPyrroloquinoline quinone is a quinone described as a cofactor for many bacterial dehydrogenases and is reported to exert an effect on metabolism in mammalian cells/tissues.
Alessio Canovai, Pete A. Williams
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Pyrroloquinoline Quinone (PQQ): Its impact on human health and potential benefits [PDF]
Current Research in Food SciencePyrroloquinoline Quinone (PQQ) is a redox-active quinone molecule with significant implications for human health. Originally identified as a bacterial cofactor, PQQ has since been lauded for its diverse biological and therapeutic activities. It serves as
Tingdong Yan +10 more
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Heliyon, 2020 Pyrroloquinoline quinone (PQQ) is contained in fruits and vegetables and in human breast milk. It has been reported that PQQ has high reactivity and changes to an imidazole structure (imidazole pyrroloquinoline) by a reaction with an amino acid at a high
Yasue Yamada, Kazuto Ikemoto
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Protective effects of pyrroloquinoline quinone in brain folate deficiency [PDF]
Fluids and Barriers of the CNS, 2023 Background Folates (Vitamin B9) are critical for normal neurodevelopment and function, with transport mediated by three major pathways: folate receptor alpha (FRα), proton-coupled folate transporter (PCFT), and reduced folate carrier (RFC).
Vishal Sangha +3 more
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Protective Effects of Pyrroloquinoline Quinone in Isoproterenol-Induced Myocardial Infarction in Rats [PDF]
Journal of Cardiovascular Development and DiseaseCardiovascular diseases remain the leading cause of mortality worldwide, with myocardial infarction (MI) representing one of the most severe manifestations.
Gülhan Ünlü +2 more
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No effect of pyrroloquinoline quinone on mouse body weight and energy metabolism with the concomitant increase in mitochondrial biogenesis and antioxidant ability [PDF]
Metabolism OpenPyrroloquinoline quinone (PQQ) stimulates mitochondrial biogenesis and exhibits antioxidant properties. Since mitochondria play a crucial role in energy generation and metabolism, the present study aims to clarify whether PQQ is able to modulate energy ...
Lijun Zhang +10 more
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Pyrroloquinoline Quinone Alleviates Tris(1,3-Dichloro-2-Propyl) Phosphate-Induced Damage During Mouse Oocyte Maturation [PDF]
AnimalsTris(1,3-dichloro-2-propyl) phosphate (TDCIPP) is a ubiquitous organophosphate flame retardant posing potential threats to reproductive health. Given that TDCIPP toxicity is often linked to oxidative stress, pyrroloquinoline quinone (PQQ), a potent ...
Lichen Sun +7 more
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Dietary pyrroloquinoline quinone and spermidine in healthy longevity: targeting the hallmarks of aging [PDF]
Frontiers in AgingBackgroundAging is a multifaceted biological process driven by interconnected cellular and molecular hallmarks. As geroscience increasingly prioritizes healthspan over lifespan, nutritional interventions targeting multiple aging mechanisms have gained ...
Tomoe Numaguchi +4 more
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Neuroprotective role of pyrroloquinoline quinone in folate deficiency-induced blood-brain barrier disruption [PDF]
Fluids and Barriers of the CNSHealthy neurodevelopment requires adequate folates (vitamin B9), which are critical for key biosynthetic and homeostatic processes in the central nervous system (CNS).
Sara Aboulhassane +3 more
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The effects of pyrroloquinoline quinone and nicotinamide mononucleotide supplementation on interoception following acute exhaustive exercise: a randomised, double-blind, placebo-controlled study [PDF]
Scientific ReportsInteroception, the process by which the nervous system perceives and interprets internal bodily signals, is essential for athletes to effectively modulate motor decisions but may be impaired after exhaustive exercise.
Chenxi Zhao +5 more
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