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Effects of pyrroloquinoline quinone and imidazole pyrroloquinoline on biological activities and neural functions [PDF]

Heliyon, 2020
Pyrroloquinoline quinone (PQQ) is contained in fruits and vegetables and in human breast milk. It has been reported that PQQ has high reactivity and changes to an imidazole structure (imidazole pyrroloquinoline) by a reaction with an amino acid at a high
Yasue Yamada, Kazuto Ikemoto
exaly   +5 more sources

Pyrroloquinoline Quinone (PQQ): Its impact on human health and potential benefits [PDF]

Current Research in Food Science
Pyrroloquinoline Quinone (PQQ) is a redox-active quinone molecule with significant implications for human health. Originally identified as a bacterial cofactor, PQQ has since been lauded for its diverse biological and therapeutic activities. It serves as
Tingdong Yan, Muhammad Farrukh Nisar, Xiaomeng Hu, Jieming Chang, Yichen Wang, Yan Wu, Zhaoguo Liu, Yi Cai, Jia Jia, Yanming Xiao, Chunpeng Wan   +10 more
exaly   +4 more sources

Protective effects of pyrroloquinoline quinone in brain folate deficiency [PDF]

Fluids and Barriers of the CNS, 2023
Background Folates (Vitamin B9) are critical for normal neurodevelopment and function, with transport mediated by three major pathways: folate receptor alpha (FRα), proton-coupled folate transporter (PCFT), and reduced folate carrier (RFC).
Vishal Sangha, Sara Aboulhassane, Qing Rui Qu, Reina Bendayan   +3 more
doaj   +2 more sources

No effect of pyrroloquinoline quinone on mouse body weight and energy metabolism with the concomitant increase in mitochondrial biogenesis and antioxidant ability [PDF]

Metabolism Open
Pyrroloquinoline quinone (PQQ) stimulates mitochondrial biogenesis and exhibits antioxidant properties. Since mitochondria play a crucial role in energy generation and metabolism, the present study aims to clarify whether PQQ is able to modulate energy ...
Lijun Zhang, Yimin Xu, Yanyan Zhao, Xiaochun Zhang, Xiangyan Liang, Zhuo Sun, Ying Zhou, Huan Liu, Jinrui Chang, Man Shi, Yufeng Zhao   +10 more
doaj   +2 more sources

Pyrroloquinoline-quinone to reduce fat accumulation and ameliorate obesity progression [PDF]

Frontiers in Molecular Biosciences, 2023
Obesity is a major health concern worldwide, and its prevalence continues to increase in several countries. Pyrroloquinoline quinone (PQQ) is naturally found in some foods and is available as a dietary supplement in its disodium crystal form.
Nur Syafiqah Mohamad Ishak, Kazuto Ikemoto   +1 more
doaj   +2 more sources

Pyrroloquinoline quinone: a potential neuroprotective compound for neurodegenerative diseases targeting metabolism [PDF]

Neural Regeneration Research
Pyrroloquinoline quinone is a quinone described as a cofactor for many bacterial dehydrogenases and is reported to exert an effect on metabolism in mammalian cells/tissues.
Alessio Canovai, Pete A. Williams
doaj   +2 more sources

Pyrroloquinoline-quinone suppresses liver fibrogenesis in mice. [PDF]

PLoS ONE, 2015
Liver fibrosis represents the consequences of a sustained wound healing response to chronic liver injuries, and its progression toward cirrhosis is the major cause of liver-related morbidity and mortality worldwide.
Dongwei Jia, Fangfang Duan, Peike Peng, Linlin Sun, Yuanyuan Ruan, Jianxin Gu   +5 more
doaj   +4 more sources

Pyrroloquinoline Quinone Alleviates Tris(1,3-Dichloro-2-Propyl) Phosphate-Induced Damage During Mouse Oocyte Maturation [PDF]

Animals
Tris(1,3-dichloro-2-propyl) phosphate (TDCIPP) is a ubiquitous organophosphate flame retardant posing potential threats to reproductive health. Given that TDCIPP toxicity is often linked to oxidative stress, pyrroloquinoline quinone (PQQ), a potent ...
Lichen Sun, Zhihong Cao, Linli Xiao, Jiahua Bai, Kexiong Liu, Yusheng Qin, Yan Liu, Xiaoling Xu   +7 more
doaj   +2 more sources

Neuroprotective role of pyrroloquinoline quinone in folate deficiency-induced blood-brain barrier disruption [PDF]

Fluids and Barriers of the CNS
Healthy neurodevelopment requires adequate folates (vitamin B9), which are critical for key biosynthetic and homeostatic processes in the central nervous system (CNS).
Sara Aboulhassane, Vishal Sangha, Md. Tozammel Hoque, Reina Bendayan   +3 more
doaj   +2 more sources

The effects of pyrroloquinoline quinone and nicotinamide mononucleotide supplementation on interoception following acute exhaustive exercise: a randomised, double-blind, placebo-controlled study [PDF]

Scientific Reports
Interoception, the process by which the nervous system perceives and interprets internal bodily signals, is essential for athletes to effectively modulate motor decisions but may be impaired after exhaustive exercise.
Chenxi Zhao, Bolong Wu, Hongtao Sui, Garry Kuan, Gaoxia Wei, Yi Yan   +5 more
doaj   +2 more sources