Results 1 to 10 of about 3,727 (217)

Cloning ofKlebsiella pneumoniae pqqgenes and PQQ biosynthesis inEscherichia coli [PDF]

FEMS Microbiology Letters, 1990
We have cloned genes from Klebsiella pneumoniae which are required for pyrroloquinoline quinone (PQQ) biosynthesis. The cloned 6.7 kb fragment can complement several chromosomal pqq mutants. Escherichia coli strains are unable to synthesize PQQ but E. coli strains containing the cloned 6.7 kb K.
J J, Meulenberg, E, Sellink, W A, Loenen, N H, Riegman, M, van Kleef, P W, Postma   +5 more
exaly   +3 more sources

Pre-conditioning with PQQ during pregnancy alleviates LPS-induced placental damage and improves the fetal survival and growth in mice [PDF]

Frontiers in Endocrinology
BackgroundIntrauterine infection is a major cause of preterm birth, fetal demise, and growth restriction. Placental damage resulting from such infections plays a central role in mediating these adverse outcomes.
Yongli Han, Yan Zhu, Xiaohui Lu, Tingting Fan, Yina Yin, Pengfei Liu, Xiuliang Dai, Hongbin Xu   +7 more
doaj   +2 more sources

Pyrroloquinoline quinone targets senescent osteoclasts and reduces spinal pain and endplate degeneration in a lumbar spine instability mouse model [PDF]

Journal of Translational Medicine
Background Pyrroloquinoline Quinone (PQQ) is a redox cofactor with potent antioxidant and anti-inflammatory properties. This study investigated the therapeutic potential of PQQ in alleviating spinal pain and degeneration in a lumbar spine instability ...
Qinghe Geng, Yan Geng, Ke Heng, Juan Zhai, Xingchen Song, Liangwei Sha, Yinuo Geng, Peiru Nie, Fanshuo Liu, Huaiyuan Zhai, Junli Huang, Yanhong Liu, Mei Li, Guoqiang Wang, Rui Geng, Kui Xue, Qilong Wang, Wanying Huang, Shuangshuang Suo, Huanyu Zhang, Ying Geng, Yuanji Yang, Junyun Lan, Hengsheng Hu, Shengnan Liu, Xiangfei Meng, Yilong Guo, Jie Li   +27 more
doaj   +2 more sources

Deciphering the assembly process of PQQ dependent methanol dehydrogenase [PDF]

Nature Communications
Pyrroloquinoline quinone (PQQ)-dependent methanol dehydrogenases (MDHs), the periplasmic metalloenzymes in Gram-negative methylotrophic bacteria, play a pivotal role in methane and methanol bio-utilization.
Haichuan Zhou, Junqing Sun, Jian Cheng, Min Wu, Jie Bai, Qian Li, Jie Shen, Manman Han, Chen Yang, Liangpo Li, Yuwan Liu, Qichen Cao, Weidong Liu, Haixia Xiao, Hongjun Dong, Feng Gao, Huifeng Jiang   +16 more
doaj   +2 more sources

No effect of pyrroloquinoline quinone on mouse body weight and energy metabolism with the concomitant increase in mitochondrial biogenesis and antioxidant ability [PDF]

Metabolism Open
Pyrroloquinoline quinone (PQQ) stimulates mitochondrial biogenesis and exhibits antioxidant properties. Since mitochondria play a crucial role in energy generation and metabolism, the present study aims to clarify whether PQQ is able to modulate energy ...
Lijun Zhang, Yimin Xu, Yanyan Zhao, Xiaochun Zhang, Xiangyan Liang, Zhuo Sun, Ying Zhou, Huan Liu, Jinrui Chang, Man Shi, Yufeng Zhao   +10 more
doaj   +2 more sources

Pyrroloquinoline Quinone Mitigates Testicular Injury and Reduces Oxidative Stress, Mitochondrial Dysfunction, and Apoptosis in Rats with Testicular Ischemia–Reperfusion Injury [PDF]

Antioxidants
Testicular torsion–detorsion (T/D) induces ischemia–reperfusion injury, leading to mitochondrial dysfunction, oxidative stress, apoptosis, and spermatogenic impairment.
Syuan-Hao Syu, Chao-Yuan Chang, Hung-Jen Shih, Chun-Jen Huang   +3 more
doaj   +2 more sources

Triple-Model Immunoassays with the Self-Assemblies of Three-in-One Small Molecules as Signaling Labels [PDF]

Biosensors
Multiple-mode immunoassays have the advantages of self-correction, self-validation, and high accuracy and reliability. In this work, we developed a strategy for the design of triple-mode immunoassays with the self-assemblies of three-in-one small ...
Zhaojiang Yu, Wenqi Yuan, Mingyi Qiao, Lin Liu   +3 more
doaj   +2 more sources

The effects of pyrroloquinoline quinone and nicotinamide mononucleotide supplementation on interoception following acute exhaustive exercise: a randomised, double-blind, placebo-controlled study [PDF]

Scientific Reports
Interoception, the process by which the nervous system perceives and interprets internal bodily signals, is essential for athletes to effectively modulate motor decisions but may be impaired after exhaustive exercise.
Chenxi Zhao, Bolong Wu, Hongtao Sui, Garry Kuan, Gaoxia Wei, Yi Yan   +5 more
doaj   +2 more sources

Pyrroloquinoline quinone promotes porcine oocyte maturation and subsequent embryo development by enhancing lipid metabolism and improving mitochondrial function [PDF]

Animal Bioscience
Objective The present study evaluated the beneficial effects of pyrroloquinoline quinone (PQQ) on in vitro maturation (IVM) of porcine oocyte and subsequent early embryo development.
Zehua Zhang, Zhigang Gao, Zhenwei Jia
doaj   +2 more sources

Pyrroloquinoline Quinone Regulates Enteric Neurochemical Plasticity of Weaned Rats Challenged With Lipopolysaccharide

Frontiers in Neuroscience, 2022
The enteric nervous system (ENS) is important for the intestinal barrier to defend and regulate inflammation in the intestine. The aim of this study was to investigate the effect of pyrroloquinoline quinone (PQQ) on regulating neuropeptide secretion by ...
Chenyu Shi, Song Xu, Caiyun Huang, Zijie Wang, Wenhui Wang, Dongxu Ming, Xindi Yin, Hu Liu, Fenglai Wang   +8 more
doaj   +1 more source