Pyrroloquinoline Quinone Improves Cognitive-Related Behavioral Performance Associated with Enhanced Mitochondrial Bioenergetics in Naturally Aged Mice [PDF]
AntioxidantsWe investigated whether pyrroloquinoline quinone (PQQ) could improve cognitive performance in twenty-month-old naturally aged mice and explored the potential mechanisms involved. Results showed that PQQ supplementation improved spatial working memory and
Yun Yan +8 more
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Protective Effects of Pyrroloquinoline Quinone in Isoproterenol-Induced Myocardial Infarction in Rats [PDF]
Journal of Cardiovascular Development and DiseaseCardiovascular diseases remain the leading cause of mortality worldwide, with myocardial infarction (MI) representing one of the most severe manifestations.
Gülhan Ünlü +2 more
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Dietary pyrroloquinoline quinone supplementation improves productive performance, immunity, and intestinal health in late-phase Jingfen No. 6 laying hens [PDF]
Poultry ScienceThis study evaluated the effects of dietary pyrroloquinoline quinone (PQQ) on the productive performance, biochemical parameters, immune function, and intestinal health of laying hens during the late laying period. A total of 360 Jingfen No.
Xuehuai Shen +12 more
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Pyrroloquinoline quinone protects heat-stressed porcine oocytes and improves early embryonic development via maintaining mitochondrial integrity and redox homeostasis [PDF]
Biology DirectHeat stress (HS) is a major environmental factor that impairs female fertility by disrupting oocyte quality and developmental competence. Pyrroloquinoline quinone (PQQ), a redox cofactor with strong antioxidant and mitochondrial-protective properties ...
Mianqun Zhang +12 more
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Pyrroloquinoline Quinone (PQQ) as a Mitochondrial Rejuvenation Strategy in Aesthetic Dermatology: Mechanisms, Therapeutic Potential, and Future Clinical Applications [PDF]
BiomoleculesBackground: Mitochondrial dysfunction is increasingly recognized as a central contributor to intrinsic skin aging, photoaging, cellular senescence, impaired extracellular-matrix homeostasis, dysregulated pigmentation, and delayed recovery after energy ...
Kyu-Ho Yi
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No effect of pyrroloquinoline quinone on mouse body weight and energy metabolism with the concomitant increase in mitochondrial biogenesis and antioxidant ability [PDF]
Metabolism OpenPyrroloquinoline quinone (PQQ) stimulates mitochondrial biogenesis and exhibits antioxidant properties. Since mitochondria play a crucial role in energy generation and metabolism, the present study aims to clarify whether PQQ is able to modulate energy ...
Lijun Zhang +10 more
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Pyrroloquinoline Quinone Mitigates Testicular Injury and Reduces Oxidative Stress, Mitochondrial Dysfunction, and Apoptosis in Rats with Testicular Ischemia–Reperfusion Injury [PDF]
AntioxidantsTesticular torsion–detorsion (T/D) induces ischemia–reperfusion injury, leading to mitochondrial dysfunction, oxidative stress, apoptosis, and spermatogenic impairment.
Syuan-Hao Syu +3 more
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Frontiers in Neuroscience, 2022 The enteric nervous system (ENS) is important for the intestinal barrier to defend and regulate inflammation in the intestine. The aim of this study was to investigate the effect of pyrroloquinoline quinone (PQQ) on regulating neuropeptide secretion by ...
Chenyu Shi +8 more
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Altering pyrroloquinoline quinone nutritional status modulates mitochondrial, lipid, and energy metabolism in rats. [PDF]
PLoS ONE, 2011 We have reported that pyrroloquinoline quinone (PQQ) improves reproduction, neonatal development, and mitochondrial function in animals by mechanisms that involve mitochondrial related cell signaling pathways.
Kathryn Bauerly +8 more
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Discovery of a eukaryotic pyrroloquinoline quinone-dependent oxidoreductase belonging to a new auxiliary activity family in the database of carbohydrate-active enzymes. [PDF]
PLoS ONE, 2014 Pyrroloquinoline quinone (PQQ) is a redox cofactor utilized by a number of prokaryotic dehydrogenases. Not all prokaryotic organisms are capable of synthesizing PQQ, even though it plays important roles in the growth and development of many organisms ...
Hirotoshi Matsumura +9 more
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