Results 21 to 30 of about 3,727 (217)

Pyrroloquinoline quinine inhibits RANKL-mediated expression of NFATc1 in part via suppression of c-Fos in mouse bone marrow cells and inhibits wear particle-induced osteolysis in mice. [PDF]

PLoS ONE, 2013
The effects of pyrroloquinoline quinine (PQQ) on RANKL-induced osteoclast differentiation and on wear particle-induced osteolysis were examined in this study.
Lingbo Kong, Chongfei Yang, Lifeng Yu, Wanli Smith, Shu Zhu, Jinyu Zhu, Qingsheng Zhu   +6 more
doaj   +1 more source

Pyrroloquinoline-Quinone Is More Than an Antioxidant: A Vitamin-like Accessory Factor Important in Health and Disease Prevention

Biomolecules, 2021
Pyrroloquinoline quinone (PQQ) is associated with biological processes such as mitochondriogenesis, reproduction, growth, and aging. In addition, PQQ attenuates clinically relevant dysfunctions (e.g., those associated with ischemia, inflammation and ...
Karen R. Jonscher, Winyoo Chowanadisai, Robert B. Rucker   +2 more
doaj   +1 more source

Dietary supplementation with pyrroloquinoline quinone promotes growth, relieves weaning stress, and regulates metabolism of piglets compared with adding zinc oxide

Animal Nutrition, 2023
Hindered growth often occurs because of psychological and environmental stress during the weaning period of piglets. This study aimed to compare the effects of growth performance, diarrhea indices, digestibility of nutrients, antioxidant capacity ...
Chenyu Shi, Zirou Yu, Zijie Wang, Ran Ning, Caiyun Huang, Youjun Gao, Fenglai Wang   +6 more
doaj   +1 more source

Pyrroloquinoline quinone regulates the redox status in vitro and in vivo of weaned pigs via the Nrf2/HO-1 pathway

Journal of Animal Science and Biotechnology, 2021
Background Oxidative stress is a main cause of piglet gut damage and diarrhea. Pyrroloquinoline quinone (PQQ), is a novel redox cofactor with antioxidant properties. However, the effect and mechanism that PQQ supplementation decreases oxidative injury in
Caiyun Huang, Zijuan Fan, Dandan Han, Lee J. Johnston, Xi Ma, Fenglai Wang   +5 more
doaj   +1 more source

Genetically Engineered Escherichia coli Nissle 1917 Synbiotics Reduce Metabolic Effects Induced by Chronic Consumption of Dietary Fructose. [PDF]

PLoS ONE, 2016
AIMS:To assess protective efficacy of genetically modified Escherichia coli Nissle 1917 (EcN) on metabolic effects induced by chronic consumption of dietary fructose.
Chaudhari Archana Somabhai, Ruma Raghuvanshi, G Nareshkumar   +2 more
doaj   +1 more source

Pyrroloquinoline Quinone Administration Alleviates Allergic Airway Inflammation in Mice by Regulating the JAK-STAT Signaling Pathway

Mediators of Inflammation, 2022
The current asthma therapies are inadequate for many patients with severe asthma. Pyrroloquinoline quinone (PQQ) is a naturally-occurring redox cofactor and nutrient that can exert a multitude of physiological effects, including anti-inflammatory and ...
Zhihui Min, Jiebai Zhou, Ruolin Mao, Bo Cui, Yunfeng Cheng, Zhihong Chen   +5 more
doaj   +1 more source

Pyrroloquinoline quinone modulates YAP-related anti-ferroptotic activity to protect against myocardial hypertrophy

Frontiers in Pharmacology, 2022
Background: Pyrroloquinoline quinone (PQQ) has been reported to exhibit cardioprotective and antioxidant activities. Accordingly, this study was developed to explore the effects of PQQ treatment on myocardial hypertrophy and the underlying mechanism of ...
Jiabin Zhou, Jiabin Zhou, Tao Yu, Tao Yu, Gujie Wu, Gujie Wu, Peng Xu, Peng Xu, Chen Wang, Yiling Su, Yiling Su, Li Wang, Li Wang, Qi Lu, Qi Lu   +14 more
doaj   +1 more source

An Efficient UPLC-MS/MS Method for the Determination of Pyrroloquinoline Quinone in Rat Plasma and Its Application to a Toxicokinetic Study

Molecules, 2022
Pyrroloquinoline quinone (PQQ) is a powerful antioxidant coenzyme existing in diet, benefiting growth, development, cognition function, and the repair of damaged organs.
Qingmei Sun, Yawen Hong, Zhaoxu Yang, Peixia He, Chao Chen, Jincheng Wang, Qinjie Weng   +6 more
doaj   +1 more source

Pyrroloquinoline quinone (PQQ) inhibits lipopolysaccharide induced inflammation in part via downregulated NF-κB and p38/JNK activation in microglial and attenuates microglia activation in lipopolysaccharide treatment mice. [PDF]

PLoS ONE, 2014
Therapeutic strategies designed to inhibit the activation of microglia may lead to significant advancement in the treatment of most neurodegenerative diseases.
Chongfei Yang, Lifeng Yu, Lingbo Kong, Rui Ma, Juliang Zhang, Qingsheng Zhu, Jinyu Zhu, Dingjun Hao   +7 more
doaj   +1 more source

Correction to “Environmental Enrofloxacin Exposure as a Modifiable Driver of Mitochondria‐Mediated Intestinal Aging and Barrier Dysfunction” [PDF]

Aging Cell
Aging Cell, Volume 25, Issue 7, July 2026.
europepmc   +2 more sources