Results 21 to 30 of about 2,765 (175)

Determination of PQQ in quinoproteins with covalently bound cofactor and in PQQ‐derivatives [PDF]

FEBS Letters, 1989
Application of the so‐called hexanol extraction procedure for PQQ determination, originally based on detachment of the cofactor from quinoproteins and conversion into PQQ‐5,5‐dihexyl ketal, leads in several cases to a number of products due to uncontrollable esterification.
van der Meer, Robert A., Mulder, Antonia C., Jongejan, Jacob A., Duine, Johannis A.   +3 more
openaire   +1 more source

Pyrroloquinoline quinone regulates the redox status in vitro and in vivo of weaned pigs via the Nrf2/HO-1 pathway

Journal of Animal Science and Biotechnology, 2021
Background Oxidative stress is a main cause of piglet gut damage and diarrhea. Pyrroloquinoline quinone (PQQ), is a novel redox cofactor with antioxidant properties. However, the effect and mechanism that PQQ supplementation decreases oxidative injury in
Caiyun Huang, Zijuan Fan, Dandan Han, Lee J. Johnston, Xi Ma, Fenglai Wang   +5 more
doaj   +1 more source

Pyrroloquinoline quinone (PQQ) inhibits lipopolysaccharide induced inflammation in part via downregulated NF-κB and p38/JNK activation in microglial and attenuates microglia activation in lipopolysaccharide treatment mice. [PDF]

PLoS ONE, 2014
Therapeutic strategies designed to inhibit the activation of microglia may lead to significant advancement in the treatment of most neurodegenerative diseases.
Chongfei Yang, Lifeng Yu, Lingbo Kong, Rui Ma, Juliang Zhang, Qingsheng Zhu, Jinyu Zhu, Dingjun Hao   +7 more
doaj   +1 more source

Pyrroloquinoline Quinone Administration Alleviates Allergic Airway Inflammation in Mice by Regulating the JAK-STAT Signaling Pathway

Mediators of Inflammation, 2022
The current asthma therapies are inadequate for many patients with severe asthma. Pyrroloquinoline quinone (PQQ) is a naturally-occurring redox cofactor and nutrient that can exert a multitude of physiological effects, including anti-inflammatory and ...
Zhihui Min, Jiebai Zhou, Ruolin Mao, Bo Cui, Yunfeng Cheng, Zhihong Chen   +5 more
doaj   +1 more source

Pyrroloquinoline quinone modulates YAP-related anti-ferroptotic activity to protect against myocardial hypertrophy

Frontiers in Pharmacology, 2022
Background: Pyrroloquinoline quinone (PQQ) has been reported to exhibit cardioprotective and antioxidant activities. Accordingly, this study was developed to explore the effects of PQQ treatment on myocardial hypertrophy and the underlying mechanism of ...
Jiabin Zhou, Jiabin Zhou, Tao Yu, Tao Yu, Gujie Wu, Gujie Wu, Peng Xu, Peng Xu, Chen Wang, Yiling Su, Yiling Su, Li Wang, Li Wang, Qi Lu, Qi Lu   +14 more
doaj   +1 more source

An Efficient UPLC-MS/MS Method for the Determination of Pyrroloquinoline Quinone in Rat Plasma and Its Application to a Toxicokinetic Study

Molecules, 2022
Pyrroloquinoline quinone (PQQ) is a powerful antioxidant coenzyme existing in diet, benefiting growth, development, cognition function, and the repair of damaged organs.
Qingmei Sun, Yawen Hong, Zhaoxu Yang, Peixia He, Chao Chen, Jincheng Wang, Qinjie Weng   +6 more
doaj   +1 more source

Correction to “Environmental Enrofloxacin Exposure as a Modifiable Driver of Mitochondria‐Mediated Intestinal Aging and Barrier Dysfunction” [PDF]

Aging Cell
Aging Cell, Volume 25, Issue 7, July 2026.
europepmc   +2 more sources

Determination of pyrroloquinoline quinone by enzymatic and LC-MS/MS methods to clarify its levels in foods.

PLoS ONE, 2018
Pyrroloquinoline quinone (PQQ) is believed to be a new B vitamin-like compound, and PQQ supplementation has received attention as a possible treatment for diseases including dementia and diabetes. However, the distribution of PQQ in foods is unclear, due
Chikara Kato, Emiko Kawai, Naoki Shimizu, Tsuyoshi Mikekado, Fumiko Kimura, Teruo Miyazawa, Kiyotaka Nakagawa   +6 more
doaj   +1 more source

Pyrroloquinoline Quinone Inhibits Rotenone-Induced Microglia Inflammation by Enhancing Autophagy

Molecules, 2020
Neuroinflammation is a feature common to neurodegenerative diseases, such as Parkinson’s disease (PD), which might be responsive to therapeutic intervention.
Qi Zhang, Jing Zhou, Mi Shen, Hui Xu, Shu Yu, Qiong Cheng, Fei Ding   +6 more
doaj   +1 more source

Effects of pyrroloquinoline quinone on noise-induced and age-related hearing loss in mice

Scientific Reports, 2022
We investigated whether the oxidoreductase cofactor pyrroloquinoline quinone (PQQ) prevents noise-induced and age-related hearing loss (NIHL and ARHL) in mice.
Ying Gao, Teru Kamogashira, Chisato Fujimoto, Shinichi Iwasaki, Tatsuya Yamasoba   +4 more
doaj   +1 more source