Results 21 to 30 of about 4,234 (212)

Determination of PQQ in quinoproteins with covalently bound cofactor and in PQQ‐derivatives [PDF]

open access: yesFEBS Letters, 1989
Application of the so‐called hexanol extraction procedure for PQQ determination, originally based on detachment of the cofactor from quinoproteins and conversion into PQQ‐5,5‐dihexyl ketal, leads in several cases to a number of products due to uncontrollable esterification.
van der Meer, Robert A.   +3 more
openaire   +1 more source

Genetically Engineered Escherichia coli Nissle 1917 Synbiotics Reduce Metabolic Effects Induced by Chronic Consumption of Dietary Fructose. [PDF]

open access: yesPLoS ONE, 2016
AIMS:To assess protective efficacy of genetically modified Escherichia coli Nissle 1917 (EcN) on metabolic effects induced by chronic consumption of dietary fructose.
Chaudhari Archana Somabhai   +2 more
doaj   +1 more source

Pyrroloquinoline quinone regulates the redox status in vitro and in vivo of weaned pigs via the Nrf2/HO-1 pathway

open access: yesJournal of Animal Science and Biotechnology, 2021
Background Oxidative stress is a main cause of piglet gut damage and diarrhea. Pyrroloquinoline quinone (PQQ), is a novel redox cofactor with antioxidant properties. However, the effect and mechanism that PQQ supplementation decreases oxidative injury in
Caiyun Huang   +5 more
doaj   +1 more source

Pyrroloquinoline Quinone (PQQ) Labeling Moieties for the Sensitive Detection of Biomolecules. [PDF]

open access: yes
Since the development of the immunoassay, biomolecule detection via binding assays has become vitally important in many fields. High sensitivity in such assays usually requires low molecular weight labeling species (i.e., tracers) that typically must be
Zimmerman, Laura B.
core   +5 more sources

Pyrroloquinoline quinone (PQQ) inhibits lipopolysaccharide induced inflammation in part via downregulated NF-κB and p38/JNK activation in microglial and attenuates microglia activation in lipopolysaccharide treatment mice. [PDF]

open access: yesPLoS ONE, 2014
Therapeutic strategies designed to inhibit the activation of microglia may lead to significant advancement in the treatment of most neurodegenerative diseases.
Chongfei Yang   +7 more
doaj   +1 more source

Pyrroloquinoline Quinone Administration Alleviates Allergic Airway Inflammation in Mice by Regulating the JAK-STAT Signaling Pathway

open access: yesMediators of Inflammation, 2022
The current asthma therapies are inadequate for many patients with severe asthma. Pyrroloquinoline quinone (PQQ) is a naturally-occurring redox cofactor and nutrient that can exert a multitude of physiological effects, including anti-inflammatory and ...
Zhihui Min   +5 more
doaj   +1 more source

Pyrroloquinoline Quinone Inhibits Rotenone-Induced Microglia Inflammation by Enhancing Autophagy

open access: yesMolecules, 2020
Neuroinflammation is a feature common to neurodegenerative diseases, such as Parkinson’s disease (PD), which might be responsive to therapeutic intervention.
Qi Zhang   +6 more
doaj   +1 more source

Pyrroloquinoline quinone modulates YAP-related anti-ferroptotic activity to protect against myocardial hypertrophy

open access: yesFrontiers in Pharmacology, 2022
Background: Pyrroloquinoline quinone (PQQ) has been reported to exhibit cardioprotective and antioxidant activities. Accordingly, this study was developed to explore the effects of PQQ treatment on myocardial hypertrophy and the underlying mechanism of ...
Jiabin Zhou   +14 more
doaj   +1 more source

RETRACTED: Pyrroloquinoline quinine inhibits RANKL-mediated expression of NFATc1 in part via suppression of c-Fos in mouse bone marrow cells and inhibits wear particle-induced osteolysis in mice.

open access: yesPLoS ONE, 2013
The effects of pyrroloquinoline quinine (PQQ) on RANKL-induced osteoclast differentiation and on wear particle-induced osteolysis were examined in this study.
Lingbo Kong   +6 more
doaj   +1 more source

Effects of pyrroloquinoline quinone on noise-induced and age-related hearing loss in mice

open access: yesScientific Reports, 2022
We investigated whether the oxidoreductase cofactor pyrroloquinoline quinone (PQQ) prevents noise-induced and age-related hearing loss (NIHL and ARHL) in mice.
Ying Gao   +4 more
doaj   +1 more source

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