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Pyrroloquinoline Quinone (PQQ): Its impact on human health and potential benefits [PDF]

Current Research in Food Science
Pyrroloquinoline Quinone (PQQ) is a redox-active quinone molecule with significant implications for human health. Originally identified as a bacterial cofactor, PQQ has since been lauded for its diverse biological and therapeutic activities. It serves as
Tingdong Yan, Muhammad Farrukh Nisar, Xiaomeng Hu, Jieming Chang, Yichen Wang, Yan Wu, Zhaoguo Liu, Yi Cai, Jia Jia, Yanming Xiao, Chunpeng Wan   +10 more
exaly   +4 more sources

Metabolic and Biochemical Effects of Pyrroloquinoline Quinone (PQQ) on Inflammation and Mitochondrial Dysfunction: Potential Health Benefits in Obesity and Future Perspectives [PDF]

Antioxidants
Obesity is defined as a complex, systemic disease characterized by excessive and dysfunctional adipose tissue, leading to adverse health effects. This condition is marked by low-grade inflammation, oxidative stress, and metabolic abnormalities, including
Vincenzo Vindigni, Giuseppe Cerullo, Tatiana Moro   +2 more
exaly   +4 more sources

Effects of Pyrroloquinoline Quinone (PQQ) on Ischemia-Reperfusion Injury in Rat Ovaries: Histological and Biochemical Assessments [PDF]

Bulletin of Emergency and Trauma, 2019
Objective: To evaluate effects of pyrroloquinoline quinone (PQQ) on ischemia-reperfusion injury using a rat ovary model.Method: Thirty healthy female Wistar rats with 250g were randomized into five experimental groups (n = 6): Group SHAM: The rats ...
Pegah Parhizkar, Rahim Mohammadi, Rasoul Shahrouz, Vahid Mohammadi   +3 more
doaj   +2 more sources

Pyrroloquinoline Quinone (PQQ) as a Mitochondrial Rejuvenation Strategy in Aesthetic Dermatology: Mechanisms, Therapeutic Potential, and Future Clinical Applications [PDF]

Biomolecules
Background: Mitochondrial dysfunction is increasingly recognized as a central contributor to intrinsic skin aging, photoaging, cellular senescence, impaired extracellular-matrix homeostasis, dysregulated pigmentation, and delayed recovery after energy ...
Kyu-Ho Yi
doaj   +2 more sources

Protective Effects of Pyrroloquinoline Quinone in Isoproterenol-Induced Myocardial Infarction in Rats [PDF]

Journal of Cardiovascular Development and Disease
Cardiovascular diseases remain the leading cause of mortality worldwide, with myocardial infarction (MI) representing one of the most severe manifestations.
Gülhan Ünlü, Kübra Tuğçe Kalkan, Seda Koçak   +2 more
doaj   +2 more sources

Pyrroloquinoline Quinone Improves Cognitive-Related Behavioral Performance Associated with Enhanced Mitochondrial Bioenergetics in Naturally Aged Mice [PDF]

Antioxidants
We investigated whether pyrroloquinoline quinone (PQQ) could improve cognitive performance in twenty-month-old naturally aged mice and explored the potential mechanisms involved. Results showed that PQQ supplementation improved spatial working memory and
Yun Yan, Di Deng, Chunxia Tan, Qi Lu, Jiutang Sun, Shaoliang Wu, Zhanhua Jiang, Yibo Li, Tao Lu   +8 more
doaj   +2 more sources

Pyrroloquinoline quinone protects heat-stressed porcine oocytes and improves early embryonic development via maintaining mitochondrial integrity and redox homeostasis [PDF]

Biology Direct
Heat stress (HS) is a major environmental factor that impairs female fertility by disrupting oocyte quality and developmental competence. Pyrroloquinoline quinone (PQQ), a redox cofactor with strong antioxidant and mitochondrial-protective properties ...
Mianqun Zhang, Qimei Xu, Bo Jia, Xue Zhang, Khienduc Lay, Mengchan Li, Yan Zou, Ziyi Wang, Xu Peng, Yang Gao, Changyin Zhou, Yanfeng Xue, Yunhai Zhang   +12 more
doaj   +2 more sources

Pyrroloquinoline Quinone and NAD⁺ Metabolism in Glaucoma: A Molecular Rationale for Combined Neuroprotection [PDF]

Pharmaceuticals
Glaucoma is the leading cause of irreversible blindness worldwide and a paradigmatic age-related neurodegenerative disease in which retinal ganglion cells (RGCs) are selectively lost through mechanisms that extend beyond intraocular pressure.
Alessandro Medoro, Sergio Davinelli, Cosimo Giuseppe Mazzotta, Luca Agnifili, Giovanni Scapagnini   +4 more
doaj   +2 more sources

Pyrroloquinoline Quinone Mitigates Type 2 Diabetes-Induced Cardiac Injury Through Mitochondrial Quality Control and Inhibition of NLRP3-Dependent Pyroptosis [PDF]

Metabolites
Background: Pyrroloquinoline quinone (PQQ), a naturally occurring redox cofactor with potent antioxidant and anti-inflammatory properties, has been shown to protect against cardiac injury.
Xue Zhang, Wei Liu, Zhijing Fu, Zhuoling Chen, Qixin Chen, Yanan Shen, Yukai Jin, Dengfeng Xu, Yin Wang, Xuefeng Qu, Yangjunna Zhang   +10 more
doaj   +2 more sources

Insights into Pyrroloquinoline Quinone (PQQ) Effects on Soil Nutrients and Pathogens from Pepper Monocropping Soil under Anaerobic and Aerobic Conditions. [PDF]

Microbiology Spectrum, 2022

exaly   +2 more sources