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Pyrroloquinoline Quinone (PQQ): Its impact on human health and potential benefits [PDF]

Current Research in Food Science
Pyrroloquinoline Quinone (PQQ) is a redox-active quinone molecule with significant implications for human health. Originally identified as a bacterial cofactor, PQQ has since been lauded for its diverse biological and therapeutic activities. It serves as
Tingdong Yan, Muhammad Farrukh Nisar, Xiaomeng Hu, Jieming Chang, Yichen Wang, Yan Wu, Zhaoguo Liu, Yi Cai, Jia Jia, Yanming Xiao, Chunpeng Wan   +10 more
exaly   +7 more sources

Metabolic and Biochemical Effects of Pyrroloquinoline Quinone (PQQ) on Inflammation and Mitochondrial Dysfunction: Potential Health Benefits in Obesity and Future Perspectives [PDF]

Antioxidants
Obesity is defined as a complex, systemic disease characterized by excessive and dysfunctional adipose tissue, leading to adverse health effects. This condition is marked by low-grade inflammation, oxidative stress, and metabolic abnormalities, including
Davide Charrier, Giuseppe Cerullo, Vincenzo Vindigni   +2 more
exaly   +4 more sources

Effects of Pyrroloquinoline Quinone (PQQ) on Ischemia-Reperfusion Injury in Rat Ovaries: Histological and Biochemical Assessments [PDF]

Bulletin of Emergency and Trauma, 2019
Objective: To evaluate effects of pyrroloquinoline quinone (PQQ) on ischemia-reperfusion injury using a rat ovary model.Method: Thirty healthy female Wistar rats with 250g were randomized into five experimental groups (n = 6): Group SHAM: The rats ...
Pegah Parhizkar, Rahim Mohammadi, Rasoul Shahrouz, Vahid Mohammadi   +3 more
doaj   +2 more sources

Characterization of a membrane-bound PQQ-dependent d-lactate dehydrogenase in Gluconobacter japonicus [PDF]

Applied Microbiology and Biotechnology
Membrane-bound pyrroloquinoline quinone (PQQ)–dependent quinoproteins are key components of the periplasmic oxidative metabolism of acetic acid bacteria, yet several predicted enzymes remain experimentally uncharacterized.
Naoya Kataoka, Shu Takeuchi, Shintaro Maeno, Minenosuke Matsutani, Kazunobu Matsushita, Toshiharu Yakushi   +5 more
doaj   +2 more sources

Development of an Engineered Bacterial Endophyte: Promoting Plant Growth Through Pyrroloquinoline Quinone (PQQ) Synthesis [PDF]

Microorganisms
Endophytic bacteria are a group of microorganisms that can intercellularly colonize plant hosts without causing apparent damage or disease. Our previous works found that a pyrroloquinoline quinone (PQQ)-producing endophyte could promote plant growth and ...
Ti Fang, Shou-Chen Lo, Yu-Ning Yu, Nga-Lai Sou, Shih-Hsun Walter Hung, Jian-Hau Peng, En-Pei Isabel Chiang, Chieh-Chen Huang   +7 more
doaj   +2 more sources

Pyrroloquinoline Quinone Mitigates Testicular Injury and Reduces Oxidative Stress, Mitochondrial Dysfunction, and Apoptosis in Rats with Testicular Ischemia–Reperfusion Injury [PDF]

Antioxidants
Testicular torsion–detorsion (T/D) induces ischemia–reperfusion injury, leading to mitochondrial dysfunction, oxidative stress, apoptosis, and spermatogenic impairment.
Syuan-Hao Syu, Chao-Yuan Chang, Hung-Jen Shih, Chun-Jen Huang   +3 more
doaj   +2 more sources

Pyrroloquinoline Quinone Mitigates Type 2 Diabetes-Induced Cardiac Injury Through Mitochondrial Quality Control and Inhibition of NLRP3-Dependent Pyroptosis [PDF]

Metabolites
Background: Pyrroloquinoline quinone (PQQ), a naturally occurring redox cofactor with potent antioxidant and anti-inflammatory properties, has been shown to protect against cardiac injury.
Xue Zhang, Wei Liu, Zhijing Fu, Zhuoling Chen, Qixin Chen, Yanan Shen, Yukai Jin, Dengfeng Xu, Yin Wang, Xuefeng Qu, Yangjunna Zhang   +10 more
doaj   +2 more sources

Dietary Pyrroloquinoline Quinone Addition Alleviated Weaning Stress via Modulation of Gut Microbiota and Metabolic Profiles in Weaned Piglets [PDF]

Animals
Weaning stress in piglets severely restricts swine production efficiency due to growth retardation, immune suppression, and intestinal dysfunction. This study investigated the effects of dietary pyrroloquinoline quinone (PQQ) on 36 weaned piglets (22 ± 1
Haocheng Xu, Xiuxi Wang, Wenwen Peng, Yashi Hu, Yangyi Xu, Xiao Xiao, Bing Dai, Ruiqiang Zhang, Yifan Zhong, Caimei Yang   +9 more
doaj   +2 more sources

Triple-Model Immunoassays with the Self-Assemblies of Three-in-One Small Molecules as Signaling Labels [PDF]

Biosensors
Multiple-mode immunoassays have the advantages of self-correction, self-validation, and high accuracy and reliability. In this work, we developed a strategy for the design of triple-mode immunoassays with the self-assemblies of three-in-one small ...
Zhaojiang Yu, Wenqi Yuan, Mingyi Qiao, Lin Liu   +3 more
doaj   +2 more sources

Pyrroloquinoline quinone targets senescent osteoclasts and reduces spinal pain and endplate degeneration in a lumbar spine instability mouse model [PDF]

Journal of Translational Medicine
Background Pyrroloquinoline Quinone (PQQ) is a redox cofactor with potent antioxidant and anti-inflammatory properties. This study investigated the therapeutic potential of PQQ in alleviating spinal pain and degeneration in a lumbar spine instability ...
Qinghe Geng, Yan Geng, Ke Heng, Juan Zhai, Xingchen Song, Liangwei Sha, Yinuo Geng, Peiru Nie, Fanshuo Liu, Huaiyuan Zhai, Junli Huang, Yanhong Liu, Mei Li, Guoqiang Wang, Rui Geng, Kui Xue, Qilong Wang, Wanying Huang, Shuangshuang Suo, Huanyu Zhang, Ying Geng, Yuanji Yang, Junyun Lan, Hengsheng Hu, Shengnan Liu, Xiangfei Meng, Yilong Guo, Jie Li   +27 more
doaj   +2 more sources