Results 11 to 20 of about 28,371 (199)

Protective Effect of Pyrroloquinoline Quinone (PQQ) against Renal Ischemia-Reperfusion Injury in Rat [PDF]

Iranian Journal of Veterinary Surgery, 2023
Ischemia/reperfusion can cause tissue damage and affect organ function. Ischemia-reperfusion injury (IRI) occurs in a variety of clinical manifestations such as stroke, trauma, and surgery.
Elnaz Taheran, Vahid Mohammadi, Rahim Mohammadi   +2 more
doaj   +3 more sources

Synthesis and crystal structure of pyrroloquinoline quinol (PQQH₂) and pyrroloquinoline quinone (PQQ)

Acta Crystallographica Section B Structural Science, Crystal Engineering and Materials, 2017
Pyrroloquinoline quinone (PQQ) is a water-soluble quinone compound first identified as a cofactor of alcohol- and glucose-dehydrogenases (ADH and GDH) in bacteria. For example, in the process of ADH reaction, alcohol is oxidized to the corresponding aldehyde, and inversely PQQ is reduced to pyrroloquinoline quinol (PQQH2).
Kazuto, Ikemoto, Shigeki, Mori, Kazuo, Mukai   +2 more
openaire   +3 more sources

Fabrication of pyrroloquinoline quinone-loaded small unilamellar vesicles through various downsizing techniques for biomedical applications

OpenNano
Treatment of injuries to bone structure represents a significant economic burden for health care institutions and systems worldwide. The development of tissue engineering scaffolds has expanded to include the incorporation of nanotechnology platforms ...
Gerardo Garcia-Zavaleta, Daniel Mejia-Valdez, Hamed Hosseinian, Ciro A. Rodriguez, Geoffrey A. Cordell, Yadira I. Vega-Cantu, Aida Rodriguez-Garcia   +6 more
doaj   +2 more sources

Pyrroloquinoline Quinone Mitigates Testicular Injury and Reduces Oxidative Stress, Mitochondrial Dysfunction, and Apoptosis in Rats with Testicular Ischemia–Reperfusion Injury [PDF]

Antioxidants
Testicular torsion–detorsion (T/D) induces ischemia–reperfusion injury, leading to mitochondrial dysfunction, oxidative stress, apoptosis, and spermatogenic impairment.
Syuan-Hao Syu, Chao-Yuan Chang, Hung-Jen Shih, Chun-Jen Huang   +3 more
doaj   +2 more sources

Deep Learning‐Driven Exploration of Pyrroloquinoline Quinone Neuroprotective Activity in Alzheimer's Disease [PDF]

Advanced Science
Alzheimer's disease (AD) is a pressing concern in neurodegenerative research. To address the challenges in AD drug development, especially those targeting Aβ, this study uses deep learning and a pharmacological approach to elucidate the potential of ...
Xinuo Li, Yuan Sun, Zheng Zhou, Jinran Li, Sai Liu, Long Chen, Yiting Shi, Min Wang, Zheying Zhu, Guangji Wang, Qiulun Lu   +10 more
doaj   +2 more sources

Coaxial nanofibers outperform uniaxial nanofibers for the loading and release of pyrroloquinoline quinone (PQQ) for biomedical applications. [PDF]

Nanoscale Adv, 2020
Pyrroloquinoline quinone (PQQ), present in breast milk and various foods, is highly recommended as an antioxidant, anti-inflammatory agent, and a cofactor in redox reactions in several biomedical fields.
Ibrahim S, Rezk MY, Ismail M, Abdelrahman T, Sharkawy M, Abdellatif A, Allam NK.   +6 more
europepmc   +2 more sources

Pyrroloquinoline Quinone Attenuates Traumatic Brain Injury-Induced Secondary Damage by Activating PINK1/Parkin-Mediated Mitophagy and Suppressing ASS1/CPS1-Driven Arginine Biosynthesis. [PDF]

CNS Neurosci Ther
Pyrroloquinoline quinone (PQQ) attenuates traumatic brain injury in mice. Multi‐omics integration and molecular docking reveal that PQQ activates PINK1/Parkin‐mediated mitophagy to restore mitochondrial homeostasis while suppressing ASS1/CPS1‐driven arginine biosynthesis to dampen neuroinflammation, identifying a dual‐axis therapeutic mechanism for TBI.
He Y, Yu L, Lu Y, Zhou Z, Li A, Wang L, Huang Z, Liu Y, Ma Y, Mi W.   +9 more
europepmc   +2 more sources

Crystal structure and characterization of pyrroloquinoline quinone disodium trihydrate [PDF]

Chemistry Central Journal, 2012
Background Pyrroloquinoline quinone (PQQ), a tricarboxylic acid, has attracted attention as a growth factor, and its application to supplements and cosmetics is underway.
Ikemoto Kazuto, Sakamoto Hitoshi, Nakano Masahiko   +2 more
doaj   +3 more sources

No effect of pyrroloquinoline quinone on mouse body weight and energy metabolism with the concomitant increase in mitochondrial biogenesis and antioxidant ability [PDF]

Metabolism Open
Pyrroloquinoline quinone (PQQ) stimulates mitochondrial biogenesis and exhibits antioxidant properties. Since mitochondria play a crucial role in energy generation and metabolism, the present study aims to clarify whether PQQ is able to modulate energy ...
Lijun Zhang, Yimin Xu, Yanyan Zhao, Xiaochun Zhang, Xiangyan Liang, Zhuo Sun, Ying Zhou, Huan Liu, Jinrui Chang, Man Shi, Yufeng Zhao   +10 more
doaj   +2 more sources

Development of an Engineered Bacterial Endophyte: Promoting Plant Growth Through Pyrroloquinoline Quinone (PQQ) Synthesis. [PDF]

Microorganisms
Endophytic bacteria are a group of microorganisms that can intercellularly colonize plant hosts without causing apparent damage or disease. Our previous works found that a pyrroloquinoline quinone (PQQ)-producing endophyte could promote plant growth and ...
Fang T, Lo SC, Yu YN, Sou NL, Hung SW, Peng JH, Chiang EI, Huang CC.   +7 more
europepmc   +2 more sources