Pyrroloquinoline quinone (PQQ) is the organic cofactor in soybean lipoxygenase‐1 [PDF]
FEBS Letters, 1988 Treatment of soybean lipoxygenase‐1 (SLO) with phenylhydrazine (PH) induced inactivation and a maximum (350 nm) in the absorption spectrum of the enzyme. To detach the product having this absorption maximum, proteolysis was required. The product appeared to be the C(5) phenylhydrazone of pyrroloquinoline quinone (PQQ).
van der Meer, Robert A. +1 more
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Journal of Animal Science and Biotechnology, 2019 Background Pyrroloquinoline quinone (PQQ), which is a water soluble, thermo-stable triglyceride-quinone, is widely distributed in nature and characterized as a mammalian vitamin-like redox cofactor.
Boru Zhang +6 more
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Pyrroloquinoline quinone (PQQ) inhibits lipopolysaccharide induced inflammation in part via downregulated NF-κB and p38/JNK activation in microglial and attenuates microglia activation in lipopolysaccharide treatment mice. [PDF]
PLoS ONE, 2014 Therapeutic strategies designed to inhibit the activation of microglia may lead to significant advancement in the treatment of most neurodegenerative diseases.
Chongfei Yang +7 more
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Frontiers in Pharmacology, 2022 Background: Pyrroloquinoline quinone (PQQ) has been reported to exhibit cardioprotective and antioxidant activities. Accordingly, this study was developed to explore the effects of PQQ treatment on myocardial hypertrophy and the underlying mechanism of ...
Jiabin Zhou +14 more
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Bioelectrocatalytic activity of reconstituted peroxidase on hemin-terminated PQQ-modified electrodes
Sensors and Actuators Reports, 2022 Efficient direct electrical communication between an enzyme redox center and an electrode is of great interest from the viewpoints of application to reagentless biosensors and biofuel cells.
Kikuo Komori, Tomoki Aikawa
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Pyrroloquinoline quinone inhibits PCSK9-NLRP3 mediated pyroptosis of Leydig cells in obese mice
Cell Death and Disease, 2023 Abnormal lipid metabolism and chronic low-grade inflammation are the main traits of obesity. Especially, the molecular mechanism of concomitant deficiency in steroidogenesis-associated enzymes related to testosterone (T) synthesis of obesity dominated a ...
Jinyuan Wang +21 more
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PLoS ONE, 2018 Pyrroloquinoline quinone (PQQ) is believed to be a new B vitamin-like compound, and PQQ supplementation has received attention as a possible treatment for diseases including dementia and diabetes. However, the distribution of PQQ in foods is unclear, due
Chikara Kato +6 more
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DETECTION METHOD OF PYRROLOQUINOLINE QUINONE (PQQ) AND PQQ-ADDUCTS BY ISOTACHOPHORESIS
Analytical Sciences, 1991 New detection method of pyrroloquinoline quinone (PQQ) and PQQ-adducts has been developed by isotachophoresis using a UV and a potential gradient detectors. The detection limits of free PQQ and PQQ-acetone adduct were about 0.1μM in the sample injection of 10μl.
GOTO, MASASHI +4 more
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Genetically Engineered Escherichia coli Nissle 1917 Synbiotics Reduce Metabolic Effects Induced by Chronic Consumption of Dietary Fructose. [PDF]
PLoS ONE, 2016 AIMS:To assess protective efficacy of genetically modified Escherichia coli Nissle 1917 (EcN) on metabolic effects induced by chronic consumption of dietary fructose.
Chaudhari Archana Somabhai +2 more
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Protective Effect of Pyrroloquinoline Quinone (PQQ) in Rat Model of Intracerebral Hemorrhage. [PDF]
Cell Mol Neurobiol, 2015 Pyrroloquinoline quinone (PQQ) has invoked considerable interest because of its presence in foods, antioxidant properties, cofactor of dehydrogenase, and amine oxidase. Protective roles of PQQ in central nervous system diseases, such as experimental stroke and spinal cord injury models have been emerged.
Lu H +6 more
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