Results 31 to 40 of about 28,371 (199)

Identification of lactate dehydrogenase as a mammalian pyrroloquinoline quinone (PQQ)-binding protein. [PDF]

Sci Rep, 2016
AbstractPyrroloquinoline quinone (PQQ), a redox-active o-quinone, is an important nutrient involved in numerous physiological and biochemical processes in mammals. Despite such beneficial functions, the underlying molecular mechanisms remain to be established.
Akagawa M, Minematsu K, Shibata T, Kondo T, Ishii T, Uchida K.   +5 more
europepmc   +3 more sources

Effects of pyrroloquinoline quinone on noise-induced and age-related hearing loss in mice

Scientific Reports, 2022
We investigated whether the oxidoreductase cofactor pyrroloquinoline quinone (PQQ) prevents noise-induced and age-related hearing loss (NIHL and ARHL) in mice.
Ying Gao, Teru Kamogashira, Chisato Fujimoto, Shinichi Iwasaki, Tatsuya Yamasoba   +4 more
doaj   +1 more source

An Efficient UPLC-MS/MS Method for the Determination of Pyrroloquinoline Quinone in Rat Plasma and Its Application to a Toxicokinetic Study

Molecules, 2022
Pyrroloquinoline quinone (PQQ) is a powerful antioxidant coenzyme existing in diet, benefiting growth, development, cognition function, and the repair of damaged organs.
Qingmei Sun, Yawen Hong, Zhaoxu Yang, Peixia He, Chao Chen, Jincheng Wang, Qinjie Weng   +6 more
doaj   +1 more source

Pyrroloquinoline-quinone to reduce fat accumulation and ameliorate obesity progression

Frontiers in Molecular Biosciences, 2023
Obesity is a major health concern worldwide, and its prevalence continues to increase in several countries. Pyrroloquinoline quinone (PQQ) is naturally found in some foods and is available as a dietary supplement in its disodium crystal form.
Nur Syafiqah Mohamad Ishak, Kazuto Ikemoto   +1 more
doaj   +1 more source

The Natural Redox Cofactor Pyrroloquinoline Quinone (PQQ) Enables Photocatalytic Radical Cyclizations. [PDF]

Angew Chem Int Ed Engl
Abstract Photoenzymatic catalysis facilitates stereoselective new‐to‐nature chemistry under mild conditions. In addition to the rational design of artificial photoenzymes, naturally occurring redox enzymes can be repurposed to promote photoredox catalysis in the chiral protein environment.
Bahukhandi SB, Klein AS, Mustafa G, Weyh M, Walter A, Thyrhaug E, Hauer J, Storch G, Zeymer C.   +8 more
europepmc   +4 more sources

Transcriptome analysis of the effect of pyrroloquinoline quinone disodium (PQQ·Na2) on reproductive performance in sows during gestation and lactation

Journal of Animal Science and Biotechnology, 2019
Background Pyrroloquinoline quinone (PQQ), which is a water soluble, thermo-stable triglyceride-quinone, is widely distributed in nature and characterized as a mammalian vitamin-like redox cofactor.
Boru Zhang, Chenxi Wang, Wei Yang, Hongyun Zhang, Qingwei Meng, Baoming Shi, Anshan Shan   +6 more
doaj   +1 more source

Ultrasensitive determination of pyrroloquinoline quinone in human plasma by HPLC with chemiluminescence detection using the redox cycle of quinone [PDF]

, 2017
A fast, accurate, and ultrasensitive high-performance liquid chromatography method with chemiluminescence detection (HPLC-CL) was optimized and validated for the determination of pyrroloquinoline quinone (PQQ) concentration in human plasma following ...
Kuroda, Naotaka, Fukuda, Mizuho, El-Maghrabey, Mahmoud H., Mizuho Fukuda, Mahmoud H. El-Maghrabey, Kazuto Ikemoto, Kishikawa, Naoya, Naoya Kishikawa, Naotaka Kuroda, Ikemoto, Kazuto   +9 more
core   +1 more source

Pyrroloquinoline quinone influences intracellular alpha-synuclein aggregates [PDF]

, 2023
Parkinson's disease (PD) is an irreversible neurodegenerative disorder clinically manifesting in uncontrolled motor symptoms. There are two primary hallmark features of Parkinson's disease - an irreversible loss of dopaminergic neurons of the substantia ...
Ghildyal, Reena, Ghildyal, Reena; id_orcid, Bugarcic, Andrea, Mountford, Elizabeth, Mathew, Cynthia   +4 more
core   +1 more source

Pyrroloquinoline quinone (PQQ) inhibits lipopolysaccharide induced inflammation in part via downregulated NF-κB and p38/JNK activation in microglial and attenuates microglia activation in lipopolysaccharide treatment mice. [PDF]

PLoS ONE, 2014
Therapeutic strategies designed to inhibit the activation of microglia may lead to significant advancement in the treatment of most neurodegenerative diseases.
Chongfei Yang, Lifeng Yu, Lingbo Kong, Rui Ma, Juliang Zhang, Qingsheng Zhu, Jinyu Zhu, Dingjun Hao   +7 more
doaj   +1 more source

Determination of pyrroloquinoline quinone by enzymatic and LC-MS/MS methods to clarify its levels in foods.

PLoS ONE, 2018
Pyrroloquinoline quinone (PQQ) is believed to be a new B vitamin-like compound, and PQQ supplementation has received attention as a possible treatment for diseases including dementia and diabetes. However, the distribution of PQQ in foods is unclear, due
Chikara Kato, Emiko Kawai, Naoki Shimizu, Tsuyoshi Mikekado, Fumiko Kimura, Teruo Miyazawa, Kiyotaka Nakagawa   +6 more
doaj   +1 more source