Results 1 to 10 of about 95,534 (148)

The Natural Redox Cofactor Pyrroloquinoline Quinone (PQQ) Enables Photocatalytic Radical Cyclizations [PDF]

Angewandte Chemie - International Edition
Abstract Photoenzymatic catalysis facilitates stereoselective new‐to‐nature chemistry under mild conditions. In addition to the rational design of artificial photoenzymes, naturally occurring redox enzymes can be repurposed to promote photoredox catalysis in the chiral protein environment.
Andreas S Klein, Erling Thyrhaug, Jürgen Hauer   +2 more
exaly   +8 more sources

Fine‐tuning ethanol oxidation pathway enzymes and cofactor PQQ coordinates the conflict between fitness and acetic acid production by Acetobacter pasteurianus [PDF]

Microbial Biotechnology, 2021
Summary The very high concentrations required for industrial production of free acetic acid create toxicity and low pH values, which usually conflict with the host cell growth, leading to a poor productivity.
, Xiaole Xia, Zhengyu Jin
exaly   +5 more sources

Deciphering the assembly process of PQQ dependent methanol dehydrogenase [PDF]

Nature Communications
Pyrroloquinoline quinone (PQQ)-dependent methanol dehydrogenases (MDHs), the periplasmic metalloenzymes in Gram-negative methylotrophic bacteria, play a pivotal role in methane and methanol bio-utilization.
Haichuan Zhou, Junqing Sun, Jian Cheng, Min Wu, Jie Bai, Qian Li, Jie Shen, Manman Han, Chen Yang, Liangpo Li, Yuwan Liu, Qichen Cao, Weidong Liu, Haixia Xiao, Hongjun Dong, Feng Gao, Huifeng Jiang   +16 more
doaj   +3 more sources

Determination of PQQ in quinoproteins with covalently bound cofactor and in PQQ-derivatives [PDF]

FEBS Letters, 1989
Application of the so‐called hexanol extraction procedure for PQQ determination, originally based on detachment of the cofactor from quinoproteins and conversion into PQQ‐5,5‐dihexyl ketal, leads in several cases to a number of products due to uncontrollable esterification.
Robert A Van Der Meer, J A Jongejan, J A Duine   +2 more
exaly   +3 more sources

Evidence for PQQ as cofactor in 3,4-dihydroxyphenylalanine (dopa) decarboxylase of pig kidney [PDF]

FEBS Letters, 1988
Pig kidney 3,4‐dihydroxyphenylalanine (dopa) decarboxylase (EC 4.1.1.28) was purified to homogeneity. Treatment of the enzyme with phenylhydrazine (PH) according to a procedure developed for analysis of quinoproteins gave products which were identified as the hydrazone of pyridoxal phosphate (PLP) and the C(5)‐hydrazone of pyrroloquinoline quinone (PQQ)
Barend W Groen, Robert A Van Der Meer, J A Duine   +2 more
exaly   +4 more sources

Pyrroloquinoline quinone (PQQ) is the organic cofactor in soybean lipoxygenase-1 [PDF]

FEBS Letters, 1988
Treatment of soybean lipoxygenase‐1 (SLO) with phenylhydrazine (PH) induced inactivation and a maximum (350 nm) in the absorption spectrum of the enzyme. To detach the product having this absorption maximum, proteolysis was required. The product appeared to be the C(5) phenylhydrazone of pyrroloquinoline quinone (PQQ).
Robert A Van Der Meer, J A Duine
exaly   +3 more sources

Endophytic Biostimulant Pyrroloquinoline Quinone Enhances Banana Growth and Primes Immunity Against Fusarium Wilt. [PDF]

Physiol Plant
ABSTRACT Pyrroloquinoline quinone (PQQ) is a redox cofactor derived from prokaryotes that participates in various biological processes involving dehydrogenase enzymes. Previous field trials identified a PQQ‐producing endophyte, Burkholderia seminalis 869T2, which enhances banana growth and reduces Fusarium wilt incidence from 24.5% to 3.4%.
Hung SW, Yu MY, Liu CH, Huang TC, Peng JH, Jang NY, Kuo CH, Yang YL, Ho YN, Chiang EI, Hwang HH, Huang CC.   +11 more
europepmc   +2 more sources

Pyrroloquinoline Quinone Mitigates Type 2 Diabetes-Induced Cardiac Injury Through Mitochondrial Quality Control and Inhibition of NLRP3-Dependent Pyroptosis [PDF]

Metabolites
Background: Pyrroloquinoline quinone (PQQ), a naturally occurring redox cofactor with potent antioxidant and anti-inflammatory properties, has been shown to protect against cardiac injury.
Xue Zhang, Wei Liu, Zhijing Fu, Zhuoling Chen, Qixin Chen, Yanan Shen, Yukai Jin, Dengfeng Xu, Yin Wang, Xuefeng Qu, Yangjunna Zhang   +10 more
doaj   +2 more sources

A Novel Genetic Engineering Approach for DON Detoxification Using a Yeast-Based Multi-Enzyme System [PDF]

Biology
Deoxynivalenol (DON), a Group III carcinogenic mycotoxin frequently detected in cereals and animal-derived food products, poses serious health risks to animals and humans.
Rong Li, Jia Song, Bo Sun, Aike Li, Shiqi Zou, Ming Liu, Linshu Jiang, Jingjing Shi, Qingming Cao, Chen Zhao, Weiwei Wang   +10 more
doaj   +2 more sources

Pyrroloquinoline quinone targets senescent osteoclasts and reduces spinal pain and endplate degeneration in a lumbar spine instability mouse model [PDF]

Journal of Translational Medicine
Background Pyrroloquinoline Quinone (PQQ) is a redox cofactor with potent antioxidant and anti-inflammatory properties. This study investigated the therapeutic potential of PQQ in alleviating spinal pain and degeneration in a lumbar spine instability ...
Qinghe Geng, Yan Geng, Ke Heng, Juan Zhai, Xingchen Song, Liangwei Sha, Yinuo Geng, Peiru Nie, Fanshuo Liu, Huaiyuan Zhai, Junli Huang, Yanhong Liu, Mei Li, Guoqiang Wang, Rui Geng, Kui Xue, Qilong Wang, Wanying Huang, Shuangshuang Suo, Huanyu Zhang, Ying Geng, Yuanji Yang, Junyun Lan, Hengsheng Hu, Shengnan Liu, Xiangfei Meng, Yilong Guo, Jie Li   +27 more
doaj   +2 more sources